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Viruses are infections species that infect a large spectrum of living systems. Although displaying a wide variety of shapes and sizes, they are all composed of nucleic acid encapsulated into a protein capsid. After virions enter the host cell, they replicate to produce multiple copies of themselves. They then lyse the host, releasing virions to infect new cells. High proliferation rate of viruses

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

Parabolic sub-sample interpolation for 2D block-matching motion estimation is computationally efficient. However, it is well known that the parabolic interpolation gives a biased motion estimate for displacements greater than |y.2| samples (y = 0, 1, …). Grid slope sub-sample interpolation is less biased, but it shows large variability for displacements close to y.0. We therefore propose to combin

Motivation: Array comparative genomic hybridization (aCGH) provides a genome- wide technique to screen for copy number alteration. The existing segmentation approaches for analyzing aCGH data are based on modeling data as a series of discrete segments with unknown boundaries and unknown heights. Although the biological process of copy number alteration is discrete, in reality a variety of biologic

The bachelor’s thesis explores end-customers’ perceptions regarding the differences between AI-based and human customer service, and the interaction factors that influence their experi-ences. With a focus on customer satisfaction and perceived problem-solving, the study aims at providing recommendations for the development and design of AI chatbots to better meet customer expectations and satisfac

Recent progress on deep learning (DL)-based medical image segmentation can enable fast extraction of clinical parameters for efficient clinical workflows. However, current DL methods can still fail and require manual visual inspection of outputs, which is time-consuming and diminishes the advantages of automation. For clinical applications, it is essential to develop DL approaches that can not onl

This thesis addresses drinking water quality and microbiology in full-scale drinking water distribution systems (DWDSs). It examines how UV irradiation and slow sand filters (SSFs) alter the water bacteriome, and how the biofilm in the DWDS affects the drinking water quality.In addition, the effects of installing a combined ultra­filtration and coagulation treatment stage on the pipe biofilm com­m