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Importance: Geographic atrophy (GA) is a progressing atrophy of the neuroretina with no treatment option. Background: Age-related malfunction of retinal microglia amplifies response towards age-related tissue stress in age-related macular degeneration. Here, we investigated monocyte CD200 expression – the circulating middleman negotiating retinal microglial activity – in a poorly understood subtyp
Previous in vitro and case–control studies have found an association between the insulin-like growth factor (IGF)-axis and bladder cancer risk. Circulating concentrations of IGF-I have also been found to be associated with an increased risk of several cancer types; however, the relationship between pre-diagnostic circulating IGF-I concentrations and bladder cancer has never been studied prospectiv
Objective: Recent study showed high chemokine CXC ligand 5 (CXCL5) is thought to be associated with insulin resistance in humans. However, evidence from large-scale populations about the relationship between serum CXCL5 level and metabolic phenotypes is scarce. Here we sought to evaluate serum CXCL5 distribution and its association with metabolic phenotypes among middle-aged and older Chinese. Res
Real-time PCR is fast, sensitive, specific, and can deliver quantitative data; however, two disadvantages are that this technology is sensitive to inhibition by food and that it does not distinguish between DNA originating from viable, viable nonculturable (VNC), and dead cells. For this reason, real-time PCR has been combined with a novel discontinuous buoyant density gradient method, called flot
Photoisomerization of 1,1′-diethyl-2,2′-carbocyanine iodide (pinacyanol) in alcohols was investigated by means of femtosecond time-resolved absorption spectroscopy. Only one out of two possible types of photoisomer was found. Viscosity-dependent kinetics indicate that the excited state dynamics consist of two parts, associated with a barrier-crossing observed in the blue side of stimulated emissio
During 2015 the struggles of people who searched to enter and move across Europe became increasingly intense with unthinkable numbers of deaths on the sea and other dangerous parts of the various alternative routes to and across Europe. Initially Europe witnessed a popular mobilisation of solidarity and demands for a humane response articulated through government officials as well as in the media.
Popular Abstract in Swedish Avhandlingen berör aktivering av koldioxid genom inskjutningsreaktioner i palladium-kol bindningar. Detta har gjorts med komplexen (PCP)PdMe och (PCP)PdCH2CHCH2. Dessa komplex har också använts i katalytisk karboxylering of ZnMe2och tributylallyltenn. Pga. transeffekten är bindningen mellan palladium och metylgruppen kraftigt försvagad vilket visar sig i det långa bindnThe present thesis deals with the activation of CO2 by insertion reactions into palladium-carbon bonds. This has been realised for the complexes {2,6-bis[(di-t-butylphosphino)methyl]benzene}palladium(II)methyl [(PCP)PdMe] and (PCP)PdCH2CHCH2. These complexes have also been used in the catalytic carboxylation of ZnMe2 and Bu3SnCH2CHCH2. Because of trans influence the palladium-methyl bond is severe
Although the negative effects of ultraviolet-B ( UV-B) radiation on the development of many amphibian species have been demonstrated, some speciessuch as the common frog ( Rana temporaria)seem to be tolerant of UV-B radiation. The amount of UV-B radiation received is likely to vary among populations of the same species, but little is known about geographic variation in UV-B tolerance. Similarly, a
AIM: To assess the prevalence of borderline isolated systolic hypertension (borderline ISH), and to examine its association with other cardiovascular risk factors. METHODS: A cross-sectional community-based study was carried out in 1993-1994 in Skara, Sweden, including 1109 randomly chosen subjects > or = 40 years old. Normotension (NT) was defined as systolic blood pressure (SBP) < 140 and diasto
OBJECTIVE - To study the effect of the short-acting insulin secretagogue nateglinide in patients with maturity-onset diabetes of the young type 3 (MODY3), which is characterized by a defective insulin response to glucose and hypersensitivity to sulfonylureas. RESEARCH DESIGN AND METHODS - We compared the acute effect of nateglinide, glibenclamide, and placebo on prandial plasma glucose and serum i
The aim of this research project was to create a bioinformatic image analysis pipeline for the investigation of lymphocytes in healthy human lungs. The lung is an important organ to study as it provides a fast way for pathogens to enter the body. Therefore, the pulmonary immune system must be further investigated in both healthy and diseased tissue. In order to do comparative studies, we need to c
Att yrka avdrag för resor till och från arbetet är det vanligaste avdraget som yrkas av flest antal deklaranter. Bestämmelserna om avdrag för arbetsresor regleras i 12 kap. 26–27 §§ IL och har genom undersökningen konstaterats vara klara och tydliga. Trots detta är det vanligt att avdrag beviljas på felaktiga grunder antingen på grund av okunskap eller fusk. Även om bestämmelserna är klara och tydTo claim a deduction for costs of travelling from home to work is the most common deduction in Sweden. The rules regarding trips from home to work are stated in 12 kap. 26–27 §§ inkomstskattelagen (1999:1229) (IL) and the study indicates that these rules are clear and consist. Despite of this, a lot of deductions are approved on incorrect grounds due cheat and ignorance. Even though the rules are
I vissa svenska kommunala grundskolor har skolavslutningar i kyrkan länge varit en tradition. Skolverket och skolinspektionen uttalar att skolavslutningar får hållas i kyrkan och att vissa religiösa inslag så som psalmsång får förekomma. I svensk lagstiftning finns dock inget direkt stöd för att skolavslutningar får hållas i kyrkan. Med anledning av detta meddelade riksdagens utbildningsutskott i In some Swedish municipal primary schools a common gathering in the local church at the end of every term is a well established tradition. The National Agencies for Education (Skolverket and Skolinspektionen) have come to the conclusion that these gatherings can take place in a church and that a certain degree of religious activities can take place, for example the singing of religious hymns. Howe
Abstract Title: Wireless Fidelity – A Scenario Analysis Authors: Mellberg Ola, Technology Management, Lund University Mårtensson Jens, Technology Management, Lund University Tutors: Andersson Jens A, Faculty of Engineering LTH Karlberg Johan, Sony Ericsson Mobile Communication AB Svensson Claes, Lund University Discussion: The most significant impacts on the telecom industry over the past decades
Background: In spare parts logistics, customers expect a high availability of spare parts from their providers. It is very critical for spare parts providers to be able to satisfy customers’ demands. It acts as a differentiator in the customer’s buying decision. Sandvik, an engineering company, is interested in improving their spare parts logistics. The case company is interested in benefits from
Det finns många typer av säkerhetsstudier. En av dessa är en så kallad konfliktstudie. När man idag gör en traditionell konfliktstudie analyserar man trafiksäkerheten, oftast utifrån video-data. Det vill säga en observering av den verkliga situationen. En traditionell konfliktstudie har gjorts av Svensson & Ekblad, (2018) på en korsning vid Heleneholmsstigen/Ystadvägen i Malmö där man byggt omThere are many types of traffic studies. One of these is a so-called conflict study. Today when you do a traditional conflict study, you usually analyze traffic safety based on video data, which is an observation of the real situation. A traditional conflict study was made by Svensson & Ekblad, (2018) at a crossing at Heleneholmsstigen/Ystadvägen in Malmö, where a bicycle crossing was rebuilt.
Since April 2017, legislation fining people in ‘encampments’ in public spaces was enacted in Copenhagen. This regulation was tightened by July 2018 be-coming an effective ban, where the subject of the fine was expelled from the administrative limits of the municipality. The measure comes as an ineffective way to deal with homelessness as it does not address the conditions that lead to it, working
How does the municipal platform Beirut Madinati challenge sectarian structures through its nuanced facilitation of radical democratization processes in Beirut and beyond? Drawing on in-depth, semi-structured interviews with electoral candidates, founders and volunteers of Beirut Madinati and an analysis of documents provided by the participants, this study argues that Beirut Madinati has facilitat
