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Background: Approximately 15% of Canadian adults live with two or more chronic diseases, many of which are obesity related. The degree to which Canadian obesity treatment guidelines are integrated into chronic disease management is unknown. Methods: We conducted a 12-min online survey among a non-probability sample of 2506 adult Canadians who met at least one of the following criteria: 1) BMI ≥30
This paper introduces a novel dataset that serves as a prototype of what we call the ‘Job Ads Database’ (JADB). The underlying job advertisements are gathered from the Swedish digitalized newspaper corpus hosted by and made accessible through the Swedish National Library (Kungliga Biblioteket). JADB enables studying how the frequency and content of job advertisements change over time and sheds new
Blood biomarkers have emerged as accurate tools for detecting Alzheimer’s disease (AD) pathology, offering a minimally invasive alternative to traditional diagnostic methods such as imaging and cerebrospinal fluid (CSF) analysis. Yet, the logistics surrounding venipuncture for blood collection, although considerably simpler than the acquisition of imaging and CSF, require precise processing and st
The construction industry is a major contributor to resource consumption and waste generation in the EU, making the transition to circular construction essential. Reuse of building products is an important circular strategy, but large-scale implementation is hindered by limited market maturity and uncertainty regarding product availability. This study aims to investigate the gap between reported a
Background: Antibody-based immunoassays have enabled quantification of very low concentrations of phosphorylated tau (p-tau) protein forms in cerebrospinal fluid (CSF), aiding in the diagnosis of AD. Mass spectrometry enables absolute quantification of multiple p-tau variants within a single run. The goal of this study was to compare the performance of mass spectrometry assessments of p-tau181, p-
Considerable time is often spent optimizing antennas to meet specific design metrics. Rarely, however, are the resulting antenna designs compared to rigorous physical bounds on those metrics. Here, we study the performance of optimized planar meander line antennas with respect to such bounds. Results show that these simple structures meet the lower bound on the radiation quality factor (Q-factor)
Riparian buffer zones (RBZs) are an important instrument for environmental policies for water and biodiversity protection in managed forests. We investigate the variation of the cost of implementing RBZs within different property size classes across the size range of non-industrial forest owner properties in Southern Sweden. Using the Heureka PlanWise decision support system, we quantified the cos
Delayed cerebral ischemia (DCI) occurs in up to one third of patients suffering from aneurysmal subarachnoid hemorrhage (aSAH). Untreated, it leads to secondary cerebral infarctions and is frequently associated with death or severe disability. After aneurysm rupture, erythrocytes in the subarachnoid space lyse and liberate free hemoglobin (Hb), a key driver for the development of DCI. Hemoglobin i
This paper examines corporate angels, small businesses that provide equity capital directly to unquoted ventures and become minority shareholders. Corporate angels have been largely ignored in entrepreneurial finance research. This novel study examines corporate angels' investment practices, goals and challenges by means of a combination of qualitative cases and a survey of 87 corporate angels. Fr
A persistent anthropocentric school of thought prevents comparative cognition from truly joining the evolutionary sciences, which often view “cognition” as an alien subject to the study of life. In this article, I argue that cognition is indeed inherent to all life and that we could study the evolution of cognitive skills like any other species-specific trait if we stop elevating convergence over
Ribosomes trapped on mRNAs during protein synthesis need to be rescued for the cell to survive. The most ubiquitous bacterial ribosome rescue pathway is trans-translation mediated by tmRNA and SmpB. Genetic inactivation of trans-translation can be lethal, unless ribosomes are rescued by ArfA or ArfB alternative rescue factors or the ribosome-associated quality control (RQC) system, which in Bacill
Digital healthcare services and digital health information, here called eHealth services, have the potential to reach people with diverse needs as both a complement to and a substitution for traditional healthcare. The access to and use of digital health information and digital healthcare services that are accessible and usable for people with impairments is a complex phenomenon.This potential is
BACKGROUND: Coronary atherosclerosis detected by imaging is a marker of elevated cardiovascular risk. However, imaging involves large resources and exposure to radiation. The aim was, therefore, to test whether nonimaging data, specifically data that can be self-reported, could be used to identify individuals with moderate to severe coronary atherosclerosis.METHODS AND RESULTS: We used data from t
Contemporary society operates beyond safe boundaries of the Earth system. Returning to a safe operating space for humanity within Earth system boundaries is a question of justice. The relevance of the economy—and thus of business—for bringing society back to a safe and just operating space highlights the importance of business ethics research for understanding the role of business in Earth system
Livscykelanalys (LCA) används för att utvärdera den potentiella miljöpåverkan av olika processer och tjänster, bland annat inom bygg- och fastighetssektorerna. Denna studie jämför tre LCA-verktyg som är speciellt utvecklade för användning inom bygg- och fastighetssektorn mot ett fjärde som är ett allmänt LCA-verktyg. En LCA görs för en fallstudie av ett flerfamiljshus där ett ventilationssystem meLife cycle assessment (LCA) is used to evaluate the potential environmental impact of different processes and services, including in the construction and real estate sectors. This study compares three LCA tools that have been specifically developed for use in the construction and real estate sectors with a fourth that is a general LCA tool. An LCA is performed for a case study of a multi-family bu
The Ph.D. dissertation consists of three connected, yet independent research articles, which focus on the implementation of circular economy principles in public procurement. Motivated by a curiosity for dynamics in processes of implementation I chose to investigate how actors related to processes of public procurement can implement the circular economy principles as a default. The aim of the diss
Background: The application of Pulsed Electric Field (PEF) to food may result in reversible or irreversible electroporation of cell membranes, depending on whether cell homeostasis is restored after resealing. Restoration of homeostasis upon reversible electroporation implies the recovery of the pre-pulse transmembrane potential and the restoration of cell metabolic functions. Enhanced membrane pe
