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PurposeThe paper aims to provide a conceptual map of how to mediate between sustainability theory and practice in higher education and how disciplinary divides can be bridged. It further looks at issues linked to knowledge views and drivers for institutional change that affect opportunities for whole institution development promoting action preparedness.Design/methodology/approachTaking its point
An automated ECG-based method may provide diagnostic support in the management of patients with acute coronary syndrome. The Olson method has previously proved to accurately identify the culprit artery in patients with acute coronary occlusion. Methods The Olson method was applied to 360 patients without acute myocardial ischemia and 52 patients with acute coronary occlusion. Results This study es
Let N be the number of members in a population. Fix any real number A≥2. We present a sequential search algorithm to estimate the exact value of N, with an error probability of at most exp(−A)+exp(−2A)+exp(−3A), regardless of the value of N.
Public Procurement for Innovation (PPI) is a powerful, underutilized demand-side innovation policy instrument that can be used to stimulate innovation, meet sectoral policy goals and mitigate grand challenges. Further research is required to analyze how PPI contributes to these goals and how it operates in practice; more case studies are needed to achieve this. We analyze a case of direct developm
Affinity-based solid-phase extraction (SPE) is an attractive low-cost sample preparation strategy for biomarker analysis. Molecularly imprinted polymers (MIPs) as affinity sorbents offer unique opportunities for affinity SPE, due to their low manufacturing cost and high robustness. A limitation is the prediction of their affinity; therefore, screening of analyte recovery and specificity within a l
The implementation of an enhanced modelling approach for fibre-reinforced composites is presented which may, in addition to the directional dependency induced by the fibres, allow the capturing of the fibre-bending stiffness. The theoretical framework is based on the introduction of higher-order gradients of the motion function as additional arguments of the energy function such that size effects
Background and purpose — Patient-reported outcome measures (PROMs) are increasingly used to evaluate results in orthopedic surgery. To enhance good responsiveness with a PROM, the minimally important change (MIC) should be established. MIC reflects the smallest measured change in score that is perceived as being relevant by the patients. We assessed MIC for the Self-reported Foot and Ankle Score (
Microfluidic techniques were applied to the separation of parasite and parasite-infected cells from blood to facilitate the detection of leishmaniasis, a disease representing a high burden in the developing world and for which new diagnostic tools are urgently needed. Leishmania mexicana promastigotes were successfully separated from red blood cells in a deterministic lateral displacement device.
Hairy cell leukemia is an uncommon hematologic malignancy characterized by pancytopenia and marked susceptibility to infection. Tremendous progress in the management of patients with this disease has resulted in high response rates and improved survival, yet relapse and an appropriate approach to retreatment present continuing areas for research. The disease and its effective treatment are associa
This study describes the design of degenerate primers and their use for synthesis of full-length avian influenza A neuramindase (NA). Each reaction was performed using either two forward primers and one reverse primer, or one forward primer and one reverse primer. Both primer combinations had comparable amplification efficiencies for all NA subtypes (1-9). A total of 115 virus strains, including b
Objectives: Measurement of lactate in fetal blood is used to assess the degree of anaerobic metabolism. The technical difficulties in obtaining enough scalp blood for analysis by a bloodgas-analyzer advocates for the use of a point-of-care device. StatStrip®Xpress™ (SSX) has shown promising properties but needs further evaluation before imp
A method for the fractionation of aerosol particles with respect to size and ability to grow with an increased relative humidity has been developed. The system consists of cascade impactors, diffusion driers, a humidifier and a temperature stabiliser. Diffusion driers were designed and the vapour penetration was modelled below 20%. A humidifier which can be operated with an output relative humidit
Antimicrobial resistance has reached alarming levels in many countries, thus leading to a search for new classes of antibiotics, such as antimicrobial peptides whose activity is exerted by interacting specifically with the microorganism membrane. In this study, we investigate the molecular-level mechanism of action for Labaditin (Lo), a 10-amino acid residue cyclic peptide from Jatropha multifida
