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ObjectiveOpen and endovascular aortic repair may be complicated by aortic vascular graft or endograft infection (VGEI). Confirming the microbiological aetiology is a key element in providing the best available treatment to patients with a VGEI. The primary aim of this study was to describe the technique of direct aneurysm sac guided aspiration (DASGA) in determining the microbiological aetiology i
The first European Stroke Organization (ESO) standard operating procedure (SOP) published in 2015 aimed at the implementation the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology to provide evidence-based guidelines for stroke management. This second ESO-SOP is aiming at further increase of the practicability of ESO guidelines and its technical implications. A
Book Review
A miniaturized thermal biosensor has been evaluated as part of a flow-injection analysis system for the determination of glucose in whole blood. Glucose was determined by measuring the heat evolved when samples containing glucose passed through a small column with immobilized glucose oxidase and catalase. Samples of whole blood (1 μl) can be measured directly, without any pretreatment. The correla
Thiol-ene photocurable systems based on a trifunctional thiol [trimethylolpropane tris-(3-mercaptopropanoate)] and two different multifunctional allyl ethers (trimethylolpropane triallyl ether and Boltorn U2, an allyl functional dendritic polyester) were examined. To these systems, small amounts (<1 wt%) of fluorinated allyl ethers were added for the modification of their surface properties. Two n
Degrowth thought and strategies suffer from a tension between viewing the state as incapable of initiating transformational change and making a political appeal to it to do precisely this via targeted eco-social policies. While a small number of academic papers has theoretically addressed this tension, there is a lack in research on the strategic implications arising from conceptualizations of the
In 2009, the International Soil Moisture Network (ISMN) was initiated as a community effort, funded by the European Space Agency, to serve as a centralised data hosting facility for globally available in situ soil moisture measurements . The ISMN brings together in situ soil moisture measurements collected and freely shared by a multitude of organisations, harmonises them in terms of units and sam
A high quality benchmark for small variants encompassing 88 to 90% of the reference genome has been developed for seven Genome in a Bottle (GIAB) reference samples. However a reliable benchmark for large indels and structural variants (SVs) is yet to be defined. In this study, we manually curated 1235 SVs which can ultimately be used to evaluate SV callers ortrain machine learning models. We devel
Ice cores are excellent archives for obtaining long and continuous 10Be records. However, traditional ice core 10Be measurements required a lot of ice (0.5–1kg) and often needed to be connected to a large and costly ice core project. These reasons have been the factors limiting the number and variety of 10Be projects and data. In this paper, we show measurements of 10Be on small samples (∼45g) of
BACKGROUND: Colorectal cancer (CRC) is the third most common cancer worldwide. This study was undertaken to evaluate survival outcomes and changes of disease outcomes of CRC patients over the last decades.METHODS: A retrospective analysis of CRC patients in Christchurch was performed in four patient cohorts at 5 yearly intervals; 1993-94, 1998-99, 2004-05 and 2009. Data on cancer location, stage,
Heparin-binding protein (HBP) is a promising biomarker for the development and severity of sepsis. To guide its use, it is important to understand the factors that could lead to false-positive or negative results, such as inappropriate release and inadequate clearance of HBP. HBP is presumably released only by neutrophils, and the organs responsible for its elimination are unknown. In this study,
Med hjälp av öppna datakällor från svenska myndigheter om vatten och mark vilka sammanställdes i ett QGIS-program var det möjligt att presentera och åskådliggöra vattenbudgeten i Lagans avrinningsområden. Den sammanlagda vattenmängden i avrinningsområdet kunde uppskattas till 9,36 km3 varav 75,9 % (7,10 km3) är grundvatten och 24,1% (2,26 km3) finns i sjöarna i området. Studien pekar på att GISbasUsing open-access data sets on water and soil from Swedish authorities and compiling them in a QGIS-programme made it possible to present and visualise the water budget of the Lagan River Catchment. Based on the estimations of the water volume in groundwater reservoirs and lakes the total maximum available volume in the Lagan River Catchment area was determined to be 9.36 km3. Of this 75.9% (7.10
In order to investigate the possible causes of premature thermal breakdown and performance degradation, several diagnostic techniques have been employed during the vertical tests of the Fine and Large Grain ESS Medium Beta prototypes cavities. The whole equipment, which includes second sound, fast thermometry, photodiode x ray detectors and external NaI scintillator and proportional counter, is he
Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the main embryonic arteries. The onset of circulation triggers several processes that provide critical external factors for HSC generation. Nevertheless, it is not fully understood how and when the onset of circulation affects HSC emergence. Here we show that in Ncx1−/− mouse embryos devoid of circulation the HSC l
The purpose of this perspective article is to critically explore the launch of the mission for 100 climate neutral cities in Europe. An overview of the mission approach in general is first presented, where key aspects and emerging critiques are identified. Second, key elements of the mission for 100 climate neutral cities in Europe are introduced along with some of its challenges and ambiguities.
Accuracy in MP2RAGE-based T1-mapping relies on knowledge of the imperfect inversion efficiency (finv) of the inversion pulse. Here we map the inversion efficiency of different adiabatic inversion pulses in human brain at 7T. We identified a mean finv=0.86, which is substantially lower than the finv=0.96 typically assumed in MP2RAGE. We further observed a lower finv in white matter (WM) than in the
