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Mapping the conformational variability in mutants of the amyloid precursor protein intracellular domain

The amyloid precursor protein intracellular domain (AICD) is an intrinsically disordered regulatory segment whose conserved YENPTY motif mediates transient interactions with multiple adaptor and signaling proteins. How sequence perturbations within this motif modulate its accessibility and interaction potential within a disordered ensemble remains poorly understood. Here, we combine small-angle X-

Conformational flexibility and transient structure of the proline-rich domain in p53

The proline-rich domain (PRD) of the tumor suppressor p53 plays a central role in modulating conformational dynamics and molecular interactions, yet its intrinsic structural behavior remains incompletely understood. Here, we combine extensive all-atom molecular dynamics simulations with biophysical validation to characterize the conformational ensemble of the p53 PRD. The domain behaves as an intr

Syllabus selp03

Brevmall Postadress Box 42, 221 00 Lund Besöksadress Allhelgona Kyrkogata 14M Telefon dir 046-222, växel 046-222 00 00 Telefax 046-222 44 34 E-post @soclaw.lu.se Samhäl lsvetenskapl iga fakul te ten Rättssoc io log iska ins t i tu t ionen A. Syllabus for SELP03 Sociology of European Law (15 credits, second cycle, A1N) The course was adopted by the Board of the Faculty of Social Science on 15 Decem

https://www.soclaw.lu.se/en/sites/soclaw.lu.se.en/files/syllabus_selp03.pdf - 2026-06-06

33.Toyota-final

33.Toyota-final ON THE EVOLUTIONARY HISTORY OF ‘YES’ AND ‘NO’ JUNICHI TOYOTA Abstract. Small words like ‘yes’ and ‘no’ play an important part in our daily communication, but do we clearly know where they come from? Their origin is rather mysterious. We do not know if we need these words at all, since some languages manage without them. For instance, speakers of Celtic languages answer affirmativel

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/ToyotaSLC2009.pdf - 2026-06-04

Om oss

Om oss | Akademikerföreningen Ingka Group/Ikano/Inter IKEA Hoppa till huvudinnehåll Öppna sökruta Öppna Huvudmeny Sök på saco.se Nyheter Kollektivavtal klart Sveriges Ingenjörer Distrikt Sydost Uppdatera dina uppgifter! Kalender Kollektivavtal Om oss Kontakt Akademikerföreningen Ingka Group/Ikano/Inter IKEA English Nyheter Kalender Kollektivavtal Om oss Sök på saco.se Start > Förtroendevald > Loka

https://www.saco.se/fortroendevald/lokalt-fackligt-arbete/lokala-akademikerforeningar/privat/akademikerforeningen-ingka-group-ikano-interikea/om-oss/ - 2026-06-05

Arbetsmiljöombud

Arbetsmiljöombud | Saco-S Umeå universitet Hoppa till huvudinnehåll Öppna sökruta Öppna Huvudmeny Sök på saco.se Om oss Saco-S-rådet Styrelse Kontakt Stöd och råd Vanliga frågor (FAQ) Arbetsplatsombud Nominering av arbetsplatsombud AO Humanistisk fakultet AO Medicinsk fakultet AO Samhällsvetenskaplig fakultet AO Teknisk-naturvetenskaplig fakultet AO Övriga Arbetsmiljöombud Lokala avtal Kalender Sa

https://www.saco.se/fortroendevald/lokalt-fackligt-arbete/lokala-akademikerforeningar/statlig-sektor/saco-s-umea-universitet/arbetsmiljoombud/ - 2026-06-05

callforpapers12

callforpapers12 Inbjudan Lärare och administrativ personal inom tekniska utbildningar på högskole- och universitetsnivå bjuds härmed in till den 7:e Pedagogiska Inspirationskonferensen, den 30 augusti 2012 vid Lunds Tekniska Högskola (LTH). Huvudsyftet är att öka möjligheterna till samverkan och till utbyte av pedagogiska erfarenheter. Organisatör är Genombrottet, LTHs pedagogiska stöd- och utveck

https://www.lth.se/fileadmin/lth/genombrottet/konferens2012/callforpapers12.pdf - 2026-06-05

No title

Verksamhetsplan 2026 Mål Saco-S i SPSM arbetar för att akademiker i myndigheten har: • Förutsättningar för inflytande • God löneutveckling • Karriärutveckling • Möjlighet till individuella förmåner • En god arbetsmiljö Aktiviteter Saco-S i SPSM ska under 2026 arbeta särskilt för: • Att bevaka att genomförda verksamhetsförändringar implementeras och följs upp utifrån realistiska och tydliga tidplan

https://www.saco.se/contentassets/9ffcb08ee87844a5af2ed9fc6e2afd74/saco-s-verksamhetsplan-for-verksamhetsaret-2026.pdf - 2026-06-05

No title

Ett professionellt stöd – till nytta för LTH VERKSAMHETSPLAN FÖR LTH:S KANSLI 2019–2020 På E-husets norra innergård drivs ett spel mellan elementen: jorden i en vall på gården, stenen lagd i en spiral, vinden i membranet uppe i luften, vat- tenvirvlar runt den svävande stenen – ett kretslopp i rörelse mellan jord och himmel. På kvällarna seglar det vita membranet över E-husets norra gård, belyst n

https://www.lth.se/fileadmin/lth/omlth/lthkansli/VP_kansli_2019.pdf - 2026-06-05

Sociala medier

Råd och stöd för dig som använder, eller funderar på att använda, sociala medier i tjänsten. Genvägar på sidan:Varför sociala medierSå kommer du igång med din kanalBild och filmInspiration, guider och trendspaningLunds universitet i sociala medierKontakta gärna närmsta kommunikatör för att diskutera om, och i så fall hur, du kan använda sociala medier i din verksamhet.Kontakta en kommunikatör Varf

https://www.medarbetarwebben.lu.se/stod-och-verktyg/kommunikation-och-grafisk-profil/sociala-medier - 2026-06-05

Linus Broström

Lecturer Contact details Email: linus [dot] brostrom [at] med [dot] lu [dot] seOrganisation Medical Ethics Room number: BMC I1216a Service point: 66 WebpageLinus Broströms profile in Lund University research portalOther affiliations Associate professor Medical Ethics Profile area member LU Profile Area: Human rights Publications Displaying of publications. Sorted by year, then title. Filter by typ

https://www.humanrights.lu.se/linus-brostrom - 2026-06-05

Eric Brandstedt

Senior lecturer Contact details Email: eric [dot] brandstedt [at] mrs [dot] lu [dot] seOrganisation Human Rights Studies Room number: LUX:A216 Service point: Hs 30 WebpageEric Brandstedts profile in Lund University research portalOther affiliations Profile area member LU Profile Area: Human rights Director of third cycle studies Human Rights Studies Profile area member LU Profile Area: Nature-base

https://www.humanrights.lu.se/eric-brandstedt - 2026-06-05

International Monetary Fund (IMF)

The International Monetary Fund (IMF) is a highly influential financial international organization that will be vital for the success of the Sustainable Development Goals (SDGs). While the IMF has been criticized by civil society actors for its negative impact on sustainable development, it is now focusing on supporting the SDGs. This support is particularly relevant when it comes to ensuring the

Accountability

Accountability is central for accelerating progress towards achieving the Sustainable Development Goals (SDGs). It means to hold powerful actors answerable for how they turn agreements into action. Governments, who hold the main responsibility for SDG implementation, can in the ideal case be held accountable by voters, parliaments, civil society, and the media, for how they address the SDGs. At th

Association Between the PRIMARY Score at Staging Prostate-specific Membrane Antigen Positron Emission Tomography and Overall Survival Among Patients with Newly Diagnosed Prostate Cancer : Findings from the International, Multicenter PROMISE Registry

The PRIMARY score was implemented in Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE) version 2 to improve accuracy for the diagnosis of clinically significant prostate cancer using prostate-specific membrane antigen (PSMA) positron emission tomography (PET). We reviewed overall survival (OS) for patients who underwent PSMA PET for initial staging to evaluate the prognostic valu

Advancing tire and road wear particles (TRWP) measurements : balancing laboratory conditions and real-world relevance

Non-exhaust emissions from the wear of brakes, tyres, and roads have become an increasing concern in recent years, already surpassing exhaust emissions by mass in many countries. However, there is a lack of studies in the scientific literature on test methods that include both real tyre and road materials. This is crucial for accurately replicating the tribological mechanisms and resulting emissio

Achieving brain clearance and preventing neurodegenerative diseases—A glymphatic perspective

Age-related neurodegenerative diseases are a growing burden to society, and many are sporadic, meaning that the environment, diet and lifestyle play significant roles. Cerebrospinal fluid (CSF)-mediated clearing of brain waste products via perivascular pathways, named the glymphatic system, is receiving increasing interest, as it offers unexplored perspectives on understanding neurodegenerative di