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Fluorescence lifetime imaging through scattering media

Fluorescence lifetime determination has proven to be useful, e.g. identification of molecules, quantitative estimation of species concentration and determination of temperatures. Lifetime determination of exponentially decaying signals is challenging if signals of different decay rates are being mixed, resulting in erroneous results. Such issues occur when the contrast of the measurement object is

Slower Auger Recombination in 12-Faceted Dodecahedron CsPbBr3 Nanocrystals

Over the past two decades, intensive research efforts have been devoted to suppressions of Auger recombination in metal-chalcogenide and perovskite nanocrystals (PNCs) for the application of photovoltaics and light emitting devices (LEDs). Here, we have explored dodecahedron cesium lead bromide perovskite nanocrystals (DNCs), which show slower Auger recombination time compared to hexahedron nanocr

A phenome-wide comparative analysis of genetic discordance between obesity and type 2 diabetes

Obesity and type 2 diabetes are causally related, yet there is considerable heterogeneity in the consequences of both conditions and the mechanisms of action are poorly defined. Here we show a genetic-driven approach defining two obesity profiles that convey highly concordant and discordant diabetogenic effects. We annotate and then compare association signals for these profiles across clinical an

B lymphocyte specification is preceded by extensive epigenetic priming in multipotent progenitors

B lymphocyte development is dependent on the interplay between the chromatin landscape and lineage-specific transcription factors. It has been suggested that B lineage commitment is associated with major changes in the nuclear chromatin environment, proposing a critical role for lineage-specific transcription factors in the formation of the epigenetic landscape. In this report, we have used chromo

Will a legacy of enhanced resource availability accelerate the soil microbial response to future climate change?

Soil microorganisms play an integral role in the regulation of carbon (C) cycling. In high-latitude ecosystems, climate warming is leading to higher plant productivity, shrub expansion and faster nutrient cycling; all of which increase resource availability to soil microorganisms. To understand how a legacy of enhanced resource availability affects the functional traits of microbial communities, a

A forecast of the Cloud

IT ses ofta som en del av lösningen för att uppnå ett hållbart samhälle genom till exempel minskat resande, optimering av industri- och jordbruksprocesser, intelligenta elmätare och smarta hem. Något man sällan reflekterar över är att ITbranschen själv också bidrar till elanvändningen. Ett nytt fenomen inom IT-världen är molnet som ger möjlighet till som det verkar outtömliga resurser i form av laInformation and communication technology (ICT) is often seen as part of the solution for a sustainable society, for example through reduced travel, optimization of industrial and agricultural processes, smart meters and smart homes. However, something usually left unconsidered is the electricity consumption of ICT itself. A new phenomenon of the ICT industry is the Cloud that enables seemingly ine

The Influence of Carboxylic Acid in Packaging Materials

Inte hur förpackningen påverkar din mat, utan hur din mat påverkar förpackningen. Resultatet av detta arbete kan komma att ligga till grund för miljövänligare förpackningar som ger maten längre hållbarhet och förbättrar möjligheterna för att transportera mat över hela världen. Tetra Pak har länge arbetat med att leverera ett smartare och miljövänligare sätt att förpacka mat med sina pappförpackniTetra Pak delivers food packing services world-wide and uses multilayer packaging materials to protect the food product from being affected by the environment. Loss of adhesion between the polymer and the aluminium layer in Tetra Paks packaging materials has proven to be a serious problem casing the package to lose its integrity and the food product to spoil. The problem is relatively unstudied bu

Workbench

It seems that people are more disconnected to the objects they own than ever before. What has changed in the last decades? People had tools and the skills to use them, but due to convenience and easy consumable entertainment, do-it-yourself was replaced by do-it-forme. Tasks we would have handled ourselves in the past are now done by a product or a service. This is disabling people. By losing ski

Är slutet nära för Privacy Shield? - En analys av huruvida Privacy Shield-beslutet är förenligt med det europeiska dataskyddet

I takt med den tekniska utvecklingen behandlas personuppgifter i allt större utsträckning och mer gränsöverskridande. Behandling och överföring av personuppgifter är förenat med en risk för att individens integritetsskydd åsidosätts. EU har en stark dataskyddslagstiftning och värnar om skydd av EU-medborgares personuppgifter. USA har inte en lika stark dataskyddslagstiftning. Samtidigt är USA enWith the fast development in information technology, personal data is increasingly being processed and interchanged cross-border. Processing and transfer of personal data is associated with a risk that the individual's privacy protection is disregarded. The EU has strong data protection legislations and a strong protection of the personal data of EU citizens. The U.S. does not have as strong

An artificial neural network to safely reduce the number of ambulance ECGs transmitted for physician assessment in a system with prehospital detection of ST elevation myocardial infarction

Background: Pre-hospital electrocardiogram (ECG) transmission to an expert for interpretation and triage reduces time to acute percutaneous coronary intervention (PCI) in patients with ST elevation Myocardial Infarction (STEMI). In order to detect all STEMI patients, the ECG should be transmitted in all cases of suspected acute cardiac ischemia. The aim of this study was to examine the ability of

Temperature-Dependent Intensity Modulated Two-Photon Excited Fluorescence Microscopy for High Resolution Mapping of Charge Carrier Dynamics

We present a temperature-dependent intensity modulated two-photon excited fluorescence microscopy technique that enables high-resolution quantitative mapping of charge carrier dynamics in perovskite microcrystal film. By disentangling the emission into harmonics of the excitation modulation frequency, we analyze the first and second order charge carrier recombination processes, including potential

Population-based incidence rate of inpatient and outpatient surgical procedures in a high-income country

Background: The WHO and the World Bank ask countries to report the national volume of surgery. This report describes these data for Sweden, a high-income country. Methods: In an 8-year population-based observational cohort study, all inpatient and outpatient care in the public and private sectors was detected in the Swedish National Patient Register and screened for the occurrence of surgery. The

The Role of PTEN Loss in Immune Escape, Melanoma Prognosis and Therapy Response

Checkpoint blockade therapies have changed the clinical management of metastatic melanoma patients considerably, showing survival benefits. Despite the clinical success, not all patients respond to treatment or they develop resistance. Although there are several treatment predictive biomarkers, understanding therapy resistance and the mechanisms of tumor immune evasion is crucial to increase the f

Stealing Knowledge in a Landscape of Learning: Conceptualizations of Jazz Education

Theoretical approaches to learning in practice-based jazz improvisation contexts include situated learning and ecological perspectives. This article focuses on how interest-driven, self-sustaining jazz learning activities can be matched against the concepts of stolen knowledge (Brown & Duguid, 1996) and landscape of learning (Bjerstedt, 2014). Based on an extensive interview study with SwedishTheoretical approaches to learning in practice-based jazz improvisation contexts include situated learning and ecological perspectives. This article focuses on how interest-driven, self-sustaining jazz learning activities can be matched against the concepts of stolen knowledge (Brown & Duguid, 1996) and landscape of learning (Bjerstedt, 2014). Based on an extensive interview study with Swedish

User value and usability of a web-based mindfulness intervention for families living with mental health problems

Mental health problems affect the patients and their families, who may also need therapeutic interventions. Mindfulness interventions have shown beneficial health effects for clinical and healthy populations. A web-based mindfulness intervention was tailored to address families' needs of support and tested in a pilot intervention study. The aim of this study was to explore the participants' experi

Sparse optimization of two-dimensional terahertz spectroscopy

Two-dimensional terahertz spectroscopy (2DTS) is a low-frequency analog of two-dimensional optical spectroscopy that is rapidly maturing as a probe of a wide variety of condensed matter systems. However, a persistent problem with 2DTS is the long experimental acquisition times, which prevent its broader adoption. A potential solution, requiring no increase in experimental complexity, is signal rec

Co-adsorption of p-mercaptobenzoic acid on silver nanoparticles enhances the plasmon-mediated coupling reaction of p-ethynylaniline

The enhancement of the electromagnetic field elicited by localized surface plasmon resonance (LSPR) is conducive to the generation of charge carriers, which have an important effect in driving many kinds of chemical reactions. Nonetheless, the short lifespan of charge carriers generated by plasmon (typically femtoseconds to nanoseconds) limits their effectiveness in promoting chemical reactions. H