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Fler medfödda hjärtfel upptäcks med utökad screening i tre steg

SUMMARYHigh prenatal detection rates of complex congenital heart defects (CHD) Aim: To analyze prenatal detection rates of complex CHD after the implementation of an expanded three-tiered screening model at the Skane University Hospitals in Lund and Malmö in 2015. Methods: Retrospective review of pregnancies screened from January 1, 2015 and being born by June 30, 2018. Complex CHD was defined as

Will a legacy of enhanced resource availability accelerate the soil microbial response to future climate change?

Soil microorganisms play an integral role in the regulation of carbon (C) cycling. In high-latitude ecosystems, climate warming is leading to higher plant productivity, shrub expansion and faster nutrient cycling; all of which increase resource availability to soil microorganisms. To understand how a legacy of enhanced resource availability affects the functional traits of microbial communities, a

Proteomic data analysis for differential profiling of the autoimmune diseases SLE, RA, SS, and ANCA-associated vasculitis

Early and correct diagnosis of inflammatory rheumatic diseases (IRD) poses a clinical challenge due to the multifaceted nature of symptoms, which also may change over time. The aim of this study was to perform protein expression profiling of four systemic IRDs, systemic lupus erythematosus (SLE), ANCA-associated systemic vasculitis (SV), rheumatoid arthritis (RA), and Sjögren's syndrome (SS), and

Sparse optimization of two-dimensional terahertz spectroscopy

Two-dimensional terahertz spectroscopy (2DTS) is a low-frequency analog of two-dimensional optical spectroscopy that is rapidly maturing as a probe of a wide variety of condensed matter systems. However, a persistent problem with 2DTS is the long experimental acquisition times, which prevent its broader adoption. A potential solution, requiring no increase in experimental complexity, is signal rec

Co-adsorption of p-mercaptobenzoic acid on silver nanoparticles enhances the plasmon-mediated coupling reaction of p-ethynylaniline

The enhancement of the electromagnetic field elicited by localized surface plasmon resonance (LSPR) is conducive to the generation of charge carriers, which have an important effect in driving many kinds of chemical reactions. Nonetheless, the short lifespan of charge carriers generated by plasmon (typically femtoseconds to nanoseconds) limits their effectiveness in promoting chemical reactions. H

Envisioning future resilient AI-enabled Flight Information Service

This paper investigates resilient performance of Air Traffic Management with future Artificial Intelligence (AI)-based tools. A case study was performed on an early prototype of an AI-enabled Flight Information Service (FIS) tool, using a survey of flight instructors and air traffic controllers, and a focus group with controllers with flying experience. The study focused on what characterizes good

AI-Enhanced High-Resolution Functional Imaging Reveals Trap States and Charge Carrier Recombination Pathways in Perovskite

Understanding and managing charge carrier recombination dynamics is crucial for optimizing the performance of metal halide perovskite optoelectronic devices. In this work, we introduce a machine learning-assisted intensity-modulated two-photon photoluminescence microscopy approach for quantitatively mapping recombination processes in MAPbBr3 perovskite microcrystalline films at micrometer-scale re

Dual conformational emission and vibrational coherence in a sulfone-embedded narrowband emitter

Organic luminescent narrowband emitters have emerged as promising candidates for wide-color-gamut displays. However, the comprehensive photo-induced structural and vibrational dynamics responsible for the spectral broadening remain poorly understood. In this study, ultrafast spectroscopy is employed to elucidate the excited state dynamics of a sulfone-embedded narrowband emitter, 2tCPD. An intrins

Theoretical investigation on enhancing the performance of dye-sensitized solar cells via system co-sensitization and extension of the π-bridge length

System co-sensitization and extension of the π-conjugated system are recognized as two key strategies for improving the performance of dye-sensitized solar cells (DSSCs). In this study, density functional theory (DFT) was employed to simulate two experimentally synthesized molecules, RK1 and D205, and to evaluate the performance of their co-sensitization system. Furthermore, molecular design was c

Gold impurity concentration in vapor-liquid-solid grown GaAs nanowires

Gold particles are commonly used as catalysts in the vapor-liquid-solid (VLS) growth of GaAs nanowires, but the incorporation of gold into the nanowires can negatively affect their electronic and optical properties. In this work, we investigate the equilibrium concentration of Au in GaAs nanowires using density functional theory calculations combined with thermodynamically assessed chemical potent

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene

Genes encoding B lineage–restricted transcription factors are frequently mutated in B-lymphoid leukemias, suggesting a close link between normal and malignant B-cell development. One of these transcription factors is early B-cell factor 1 (EBF1), a protein of critical importance for lineage specification and survival of B-lymphoid progenitors. Here, we report that impaired EBF1 function in mouse B

Elucidating the origin of open-circuit voltage in ternary organic solar cells with a nonfullerene and a fullerene acceptor

With organic solar cells surpassing 20% efficiency, the focus is shifting toward understanding the more complex mechanisms in ternary blends. This work investigates the distinct working principles of ternary organic solar cells based on a polymer donor (D) and a nonfullerene acceptor (NFA), with a fullerene acceptor (FA) as the third component. A systematic comparison between ternary D:NFA:FA syst

Mentorskapsprogrammet 0

SI-MENTORSKAP SI-programmet vid KEG På KEG erbjuds SI-programmet på följande kurser/program till våren 2016:  Humanekologi: Miljö, kultur och utveckling, grundkurs  Kandidatprogrammet i utvecklingsstudier (BIDS) Vill du bli SI-mentor till hösten 2016 och studerar/har studerat samhällsgeografi, humanekologi eller utvecklingsstudier? Kontakta elin.brudin@keg.lu.se för mer information. Mentorn ska

https://www.keg.lu.se/sites/keg.lu.se/files/mentorskapsprogrammet_0.pdf - 2026-05-25

Stealing Knowledge in a Landscape of Learning: Conceptualizations of Jazz Education

Theoretical approaches to learning in practice-based jazz improvisation contexts include situated learning and ecological perspectives. This article focuses on how interest-driven, self-sustaining jazz learning activities can be matched against the concepts of stolen knowledge (Brown & Duguid, 1996) and landscape of learning (Bjerstedt, 2014). Based on an extensive interview study with SwedishTheoretical approaches to learning in practice-based jazz improvisation contexts include situated learning and ecological perspectives. This article focuses on how interest-driven, self-sustaining jazz learning activities can be matched against the concepts of stolen knowledge (Brown & Duguid, 1996) and landscape of learning (Bjerstedt, 2014). Based on an extensive interview study with Swedish

Population-based incidence rate of inpatient and outpatient surgical procedures in a high-income country

Background: The WHO and the World Bank ask countries to report the national volume of surgery. This report describes these data for Sweden, a high-income country. Methods: In an 8-year population-based observational cohort study, all inpatient and outpatient care in the public and private sectors was detected in the Swedish National Patient Register and screened for the occurrence of surgery. The

The Role of PTEN Loss in Immune Escape, Melanoma Prognosis and Therapy Response

Checkpoint blockade therapies have changed the clinical management of metastatic melanoma patients considerably, showing survival benefits. Despite the clinical success, not all patients respond to treatment or they develop resistance. Although there are several treatment predictive biomarkers, understanding therapy resistance and the mechanisms of tumor immune evasion is crucial to increase the f

Metabolism of 3H labelled arachidonic acid and 14C labelled linoleic acid in essential fatty acid deficient rats

Mesenteric duct chylomicrons labelled with [3H]arachidonic (20:4) and [14C]linoleic (18:2) acid were injected intravenously into essential fatty acid-deficient (EFAD) and control rats. The rats were killed after 5, 10, 20 and 240 min, and serum and different organs were analysed for radioactivity of different lipid classes. 3H and 14C in the triacylglycerol (TG) and phosphatidylethanolamine (PE) f

Precision medicine in complex diseases - : Molecular subgrouping for improved prediction and treatment stratification

Complex diseases are caused by a combination of genetic, lifestyle, and environmental factors and comprise common noncommunicable diseases, including allergies, cardiovascular disease, and psychiatric and metabolic disorders. More than 25% of Europeans suffer from a complex disease, and together these diseases account for 70% of all deaths. The use of genomic, molecular, or imaging data to develop

Fluorescence lifetime imaging through scattering media

Fluorescence lifetime determination has proven to be useful, e.g. identification of molecules, quantitative estimation of species concentration and determination of temperatures. Lifetime determination of exponentially decaying signals is challenging if signals of different decay rates are being mixed, resulting in erroneous results. Such issues occur when the contrast of the measurement object is