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Background: A reproducible standard for a graded allergen response in allergic rhinitis is lacking. The aim was to evaluate basophil allergen threshold sensitivity, CD-sens, as a diagnostic complement to nasal allergen challenge. Methods: Twenty-six patients with a history of allergic rhinitis due to grass pollen were intranasally challenged and nasal symptom score and peak nasal inspiratory flow
Aggrecan fragments are released from human joint cartilage matrix into joint fluid after injury and in osteoarthritis (OA). The temporal patterns of release agree with changes in synthesis and degradation of aggrecan found in experimental animal models of OA. However, we are far from being able to use these molecular fragments to monitor human OA. The structures of the aggrecan fragments remaining
This study aims to gain a greater insight into cycling as an element of mobility among those in later life. The characteristics and views of those who cycle, those who have never cycled, as well as those who have discontinued cycling in later life are the main focus. Malmö, a city in the south of Sweden with a strong emphasis on bicycle planning, is the study area. This study employed a mixed meth
We investigate the mechanisms of knowledge governance and show that the actual economic benefits stemming from knowledge externalities depend on the characteristics of (a) the sources of such externalities, (b) the context in which spillovers take place, (c) the potential users of the externalities. In the Italian experience of 1950-1994, state owned enterprises (SOE) have been one of the most eff
In the present study, we have characterized the dihydrolipoamide dehydrogenase (DLDH) of Strepto-coccus pneumoniae and its role during pneumococcal infection. We have also demonstrated that a lack of DLDH results in a deficiency in alpha-galactoside metabolism and galactose transport. DLDH is an enzyme that is classically involved in the three-step conversion of 2-oxo acids to their respective acy
Aims: The study investigated whether people with mobility disability (MD) and/or obesity had higher job strain than people without it, and whether social support at work modifies this association. Methods: The study included 35,160 individuals (25-64 years of age) from the Stockholm Public Health Surveys of 2006 and 2010. Data on MD and obesity (BMI ≥ 3/4 30 kg/m2 calculated from weight (kg) and h
Transition to adulthood, referring to the process of moving from childhood to adulthood, can be a complex period for youths with disabilities who might need special support transitioning into an independent life as adults. Caregivers are significant persons for the youths, which is why their own health and wellbeing is important. Therefore the overall aim of this thesis was to gain a deeper unders
A patient with a myelodysplastic syndrome ([MDS], i.e., refractory anemia with ring sideroblasts [RARS]) and a rapidly fatal clinical course is presented. A cytogenetic analysis showed an isochromosome 17q as a sole abnormality in all metaphases. An association between RARS and i(17q) has not been reported. Furthermore, a mutation of the remaining TP53 gene in exon 6 was evidenced by a single stra
OBJECTIVE: Smoking is an established risk factor for type 2 diabetes. In contrast, it has been proposed that smoking may reduce the risk of latent autoimmune diabetes in adults (LADA), but studies are scarce. We aimed to study the impact of smoking on LADA and type 2 diabetes risks. RESEARCH DESIGN AND METHODS: We used data from a Swedish case-control study including incident case patients with LA
This article discusses the current self-confidence and apparent success—at least by market/popularity measures—of leadership studies (LS) in general and transformational leadership (TFL) in particular. An alternative interpretation is offered, suggesting that it is the ideological character of these approaches that account for their “success,” at least in quantitative terms. Their wide appeal need
In this article, we respond to Cabantous, Gond, Harding and Learmonth’s (2016) critique of recent conceptual contributions that employ the concept of performativity for prompting progressive changes in organizations. All in all, we seem to share the general unease concerning the marginal impact of Critical Management Studies on re-defining organizational realities. At the same time, we largely dis
OBJECTIVES: The aim of this study was twofold: (i) to evaluate the air levels of N-nitrosamines in the Swedish rubber industry and (ii) to estimate the risk of symptoms and changed levels of immunologic markers in relation to these levels.METHODS: Using adsorption tubes, we collected samples of N-nitrosamines in the breathing zone of 96 rubber workers and analyzed them with liquid chromatography t
Objectives: Study formal and informal care of community-living older people in the Swedish National study of Aging and Care (SNAC). Design: Cross-sectional, population based cohort. Setting: Three areas in Sweden: Municipality of Nordanstig, Stockholm and Skåne County. Participants: 3,338 persons ≥72 years. Measurements: Patterns and amounts of informal and formal care by cognition and area of res
