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BACKGROUND: Malignancies of the liver and bile ducts are associated with high recurrence rates after surgery and poor prognosis when disseminated. Medical treatment has been improved in recent years, with chemotherapy, targeted therapy and checkpoint inhibitors offering opportunities to influence the course of the diseases. Many patients do not benefit from treatment, however, and predictive and p
Current trends aim at improving the surface integrity of aerospace Ni-based superalloys by reducing the temperature rise in the cutting zone in order to minimize tool wear, as well as reducing the thermally induced tensile residual stresses on the machined surface. The manufacturing industry is also driven by developing high performance sustainable machining processes. Cryogenic machining (CM) usi
This viewpoint advocates for the inclusion of art in global health discourse and practice. We explore four areas in which art can be leveraged to improve global health: (1) to amplify disenfranchised voices, (2) to advance social justice activism, (3) to strengthen communities and individuals, and (4) to improve global health communication. Drawing on community-driven art initiatives, we argue for
Compassion fatigue (CF), a diminished empathic capacity resulting from prolonged exposure to others’ distress, is an emerging concern in the teaching profession. This study investigates the prevalence and predictors of CF among Swedish teachers, with a particular focus on reduced compassion toward students. Drawing on the job demands-resources model and the compassion fatigue resilience model, we
The associated production of Higgs and W bosons via vector-boson fusion is highly sensitive to the relative sign of the Higgs boson couplings to W and Z bosons. In this Letter, two searches for this process are presented, using 140 fb^{-1} of proton-proton collision data at sqrt[s]=13 TeV recorded by the ATLAS detector at the LHC. The first search targets scenarios with opposite-sign couplings o
In Memoriam
This study investigates the wages and labour contracts of Khoe workers in Graaff Reinet, a district on the Cape Colony’s eastern frontier in the early nineteenth century. Using wage registers from 1801 to 1810, we offer the first individual-level analysis of wages for both male and female Khoe workers, examining payment forms, socio-economic stratification, and gendered wage dynamics. The findings
Objective: To describe the clinical and ultrasound characteristics of serous and mucinous cystadenomas in the adnexa. Methods: This was a retrospective international multicenter study. Using the International Ovarian Tumor Analysis (IOTA) database, patients with a histological diagnosis of serous or mucinous cystadenoma who had undergone preoperative ultrasound examination between 1999 and 2016 (I
Retrieving episodic memories often involves reconstructing both their semantic content and the emotional context in which they occurred. However, the neural mechanisms that differentiate these forms of reinstatement remain poorly understood. This event-related potential (ERP) study examines how semantic category and emotional valence are reinstated during memory retrieval.Seventy participants enco
Executive functions are a set of cognitive skills enabling goal‑directed behaviours. Both mammals and birds have highly proficient executive functions, despite diverging from each other around 360 million years ago. This cognitive convergence is due to both taxa being tachymetabolic endotherms. They can maintain a stable and elevated body temperature with a high metabolism. However, in order to su
Climate change-induced water insecurity impacts are unevenly distributed across the world, with Africa expected to bear the highest burden of water scarcity globally. This chapter examines how climate change acts as a compounding factor that exacerbates the existing vulnerabilities in the Sahel region and creates new challenges for water security and irrigation management. With populations in the
Background We investigate whether, in Swedish national registers, social and psychiatric outcomes for six major psychiatric and substance disorders - drug use disorder (DUD), alcohol use disorder (AUD), major depression (MD), bipolar disorder (BD), anxiety disorder (AD), and schizophrenia (SZ) - reflect the primary genetic risk for each disorder and the level of genetic heterogeneity. Methods We u
Low-energy-electron emission from resonant Auger final states via intermolecular Coulombic decay (RA-ICD) has previously been described as a promising scenario for controlling radiation damage for medical purposes, but it has so far only been observed in prototypical atomic and molecular van der Waals dimers and clusters. Here, we report the experimental observation of RA-ICD in an aqueous solutio
Scholarship in the last decades has increasingly paid attention to the rhetoric of race and peoplehood in early Christian literature. It has been shown how the construction of Christian identity took place through ethnic reasoning, with writers using metaphors of parenthood, kinship, homeland and descent to express what it meant to be a Christian. These studies have typically focused on pre-Consta
Accountability is central for accelerating progress towards achieving the Sustainable Development Goals (SDGs). It means to hold powerful actors answerable for how they turn agreements into action. Governments, who hold the main responsibility for SDG implementation, can in the ideal case be held accountable by voters, parliaments, civil society, and the media, for how they address the SDGs. At th
Gallstone disease is common in the Western world, and approximately 15,000 cholecystectomies and 9000 endoscopic retrograde cholangiopancreatographies (ERCPs) are performed each year in Sweden. While being safe, the high frequency of these procedures has a significant cumulative impact on health in the community, exceeding those of many complex procedures for malignant conditions. Compliance with
Purpose: The Paleolithic Diet Fraction (PDF) estimates the proportion of absolute dietary intake derived from food groups included in the Paleolithic diet. In the Malmö Diet and Cancer Study (MDCS), higher PDF and lower systemic low-grade chronic inflammation (SLGCI) have been associated with lower cardiometabolic morbidity and mortality. We examined associations between PDF and SLGCI in the MDCS.
Explicit finite element schemes are extensively used in industrial applications characterised by elevated strain rates and complex contact interactions. A central challenge in such simulations is the achievement of mesh-independent results while accurately capturing damage localisation and evolution. Gradient-enhanced damage models provide a robust regularisation framework. However, using a microm
Background: The dairy industry has gradually adopted cutting-edge technology in the past few years. This review explores the evolution and interventions of Artificial Intelligence (AI), Machine Learning (ML), and Industry 4.0 in the dairy industry through a systematic literature review and bibliometric analysis. Methods: The Web of Science, Scopus, etc. databases were used for bibliometric analysi
