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This study describes how the serum protein histidine-rich glycoprotein (HRG) affects the complement system. We show that HRG binds strongly to several complement proteins: C1q, factor H and C4b-binding protein and that it is found complexed with these proteins in human sera and synovial fluids of rheumatoid arthritis patients. HRG also binds C8 and to a lesser extent mannose-binding lectin, C4 and
Denna uppsats utgår från premissen att barns rätt till integritet är en del av barns rätt till deltagande online. Barnrättslagstiftning presenterar i sig ett di-lemma som rör barns rätt till delaktighet och skydd, där en rättighetsbaserad strategi anses vara det mest effektiva sättet att ta itu med dilemmat. En rättig-hetsbaserad strategi förespråkar en balans mellan barns behov av skydd online ocThis thesis starts from the premise that children’s right to privacy is a part and parcel for children’s right to participation online. Children’s rights law inher-ently presents a dilemma relating to children’s right to participation and protec-tion, where a rights-based approached is considered the most effective way to address the dilemma. A rights-based approach is legal framework that can bal
In this global ‘age of autonomy’ this thesis will discuss the relation between indigenous peoples autonomy, their political agency and the national environmental agenda in the Plurinational State of Bolivia and in Sweden. With decolonial critique of development the cases will be analysed looking at factors such as indigenous rights policy, resource management, conservation agendas and the structur
The use of bicycles in a mid-sized city – benefits and obstacles identified using a questionnaire and GIS The need for alternative means of transport is highlighted by many studies. This need can be satisfied by prioritizing the use of bicycles over the use of mechanical vehicles in daily mobility needs in a city. Here we show an investigation of ways of improving this prioritization in a middle-
This paper introduces machine learning to automate the coarsening choices in coarsened exact matching (CEM) as a monotonic imbalance bounding matching class. I suggest to replace the otherwise arbitrary multivariate stratification process with a binary classification tree. This way, I can minimise potential bias caused by subjective preferences. By using the LaLonde (1986) dataset, I systematicall
Artificial Intelligence (AI) technology advances quickly through society, with driverless cars presented as a revolutionary technological advance that can make roads safer and transport more efficient, whereas automated weapons are either viewed as undesirable, or as an unavoidable development. The objective of the present work is to, through the comparison between automated driving and automated
This paper focuses on the effect of Bilateral Investment Treaties and Preferential Trade and Investment Agreements on outwards FDI stocks of developed countries (proxied by OECD countries) in one another in the period of 1985-2013. Estimations are obtained with use of the gravity equation in a large panel based on OECD FDI positions data, where the “knowledge-and-physical-capital model” of interna
The rat urinary bladder responded to infravesical obstruction by an increased weight. The weight began to increase after 3 days of obstruction. After 10 days the weight gain had become significant, but increased further with time. At 90 days the bladders weighed 12 times the initial weight. Lactate dehydrogenase (LDH) activity per unit bladder weight increased with the duration of the obstruction.
La chimie des otolithes de poissons sert a associer les poissons a des environnements specifiques. La chimie des otolithes peut aussi potentiellement servir d'outil dans la recherche phylogenetique, comme nous le demontrons ici chez les poissons salmonides et les taxons apparentes. Des cartes bidimensionnelles de la chimie de Zn:Ca dans les otolithes montrent des oscillations annuelles d'amplitude
In the production of ethanol from lignocellulosic material, it is necessary to reach a high ethanol concentration after fermentation. Simply increasing the substrate concentration leads to stirring problems and inhibition of the enzymes and yeast in the process. Batch simultaneous saccharification and fermentation (SSF) of steam-pretreated spruce with 13.7% water-insoluble solids (WIS) (25% total
Contour feathers cover most of the avian body and play critical roles in insulation, social communication, aerodynamics, and water repellency. Feather production is costly and the development of the optimum characteristics for each function may be constrained by limited resources or time, and possibly also lead to trade-offs among the different characteristics. Populations exposed to different env
The present study aimed to investigate how the impact of several factors linked to geography would shape life-history traits in a gregarious species, using the pine processionary moth (PPM) Thaumetopoea pityocampa as a model system. PPM has a wide geographical distribution over the Mediterranean Basin, and it is a strictly gregarious species throughout larval development, where the total reproduct
The spatial distribution of predators and their prey is affected by their joint use of space. While the formation of such spatial patterns may be driven by density-dependent and -independent factors our knowledge on the contribution of different land-use activities on the formation of spatial patterns between predators and prey remains very limited. Agriculture is one of the most prevailing land-u
BACKGROUND: Oral contraceptive use and reproductive factors may initiate long-term changes to the hormonal milieu and thereby, possibly influence colorectal cancer risk. METHODS: We examined the association of hormonal and reproductive factors with risk of colorectal cancer among 337 802 women in the European Prospective Investigation into Cancer and Nutrition, of whom 1878 developed colorectal ca
A study of the influence of spin-orbit coupling and dynamical electron correlation on the polarizabilities of the halogen atoms in a variational treatment is presented. It is shown that for the heavier homologs it is necessary to replace the averaged values by individual component polarizabilities for the J=3/2 and J=1/2 atomic states due to the large spin-orbit coupling. A high level of correlati
Microzarkodina is a genus of mainly Middle Ordovician conodonts that has its centre of distribution in Baltoscandia, and much less commonly occurs in southern China, Australia, Argentina and Laurentia. In Baltica a series of species, Microzarkodina russica n. sp., M. flabellum, M. parva, M. Bella, M. Hagetiana and M. ozarkodella, established themselves successfully. The succession of species range
Flow cytometry, morphometry and molecular markers [plastid DNA and internal transcribed spacers(ITS) of nuclear ribosomal DNA] were used to determine taxonomic and phylogeographic patterns in Dactylorhiza maculata s.l. from Scandinavia. A total of 238 individuals from 27 populations from throughout all of Scandinavia, including the adjacent Kola Peninsula of Russia, were analyzed. Diploid D. macul
The glpTQ operon of Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) strains is highly conserved, except for a 1.4-kb glpTQ intergenic region that was found in most Hib strains. The presence of this intergenic region results in divergent glpTQ transcriptional profiles for Hib and NTHi where Hib strains appear to have evolved an alternative promoter for glpQ expression. Base
The phase behavior and aggregation properties of a triblock copolymer of ethylene oxide (EO) and propylene oxide (PO), with a measured composition (EO)29(PO)40(EO)29, in aqueous solutions containing salt, have been examined using dynamic light scattering, rheological techniques, and sedimentation and viscosity measurements. The copolymer is dissolved as a unimer at low temperatures and forms spher
