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Slaughter transportation of pigs can be considered a high-risk occupation, but has received very little scientific attention. We investigated the effect of a training intervention on transport drivers’ physical workload, in terms of postures and movements, and time efficiency during loading of finishing pigs for slaughter transport. The training targeted pig handling and ergonomic working principl
Background: Intermediate care is often defined as healthcare occurring somewhere between traditional primary (community) and secondary (hospital) care settings. High quality intermediate care is important in dementia, may prevent caregiver burnout and also lead to optimal care for people with dementia. However, very little is known about the point of intermediate care for persons with dementia in
Patient-derived cells hold great promise for precision medicine approaches in human health. Human dermal fibroblasts have been a major source of cells for reprogramming and differentiating into specific cell types for disease modeling. Postmortem human dura mater has been suggested as a primary source of fibroblasts for in vitro modeling of neurodegenerative diseases. Although fibroblast-like cell
AXL, a member of the TAM family, is a promising therapeutic target due to its elevated expression in advanced hepatocellular carcinoma (HCC), particularly in association with acquired drug resistance. Previously, RNA interference was used to study its role in cancer, and several phenotypic changes, including attenuated cell proliferation and decreased migration and invasion, have been reported. Th
Evaluating the structure of soil prior to building construction is valuable in a large variety of geotechnical and civil engineering applications. To built an effective framework for assessing the strength of the stabilised soil, the presented workflow includes a complex approach of simplex lattice design and X-ray diffraction for the analysis of soil structure. Different from the traditional in s
Background: Prediction tools that combine polygenic risk scores with clinical factors provide a new opportunity for improved prediction and prevention of atherosclerotic cardiovascular disease, but the clinical utility of polygenic risk score has remained unclear. Methods: We collected a prospective cohort of 7342 individuals (64% women, mean age 56 years) and estimated their 10-year risk for athe
Neurodegenerative disorders are common and heterogeneous in terms of their symptoms and cellular affectation, making their study complicated due to the lack of proper animal models that fully mimic human diseases and the poor availability of post-mortem human brain tissue. Adult human nervous tissue culture offers the possibility to study different aspects of neurological disorders. Molecular, cel
A fundamental problem in radiotherapy is the variation of organ at risk (OAR) volumes. Here we present our initial experience in engaging a large Radiation Oncology (RO) community to agree on national guidelines for OAR delineations. Our project builds on associated standardization initiatives and invites professionals from all radiotherapy departments nationwide. Presently, one guideline (rectum)
Here a lung-on-a-chip device was developed and fabricated using 3D-printing of molds. The lung-on-a-chip device was used as a lung injury model by overstretching of murine lung epithelial cells (MLE-12) monolayers, resembling the injury during mechanical ventilation. The cells were exposed to 25% strain, representing pathological conditions seen in ventilator induced lung injury of patients with
Olika motiv kan influera individen till att vilja bli vegetarian, men däremot kan olika individer motiveras av olika motiv (Rosenfeld & Burrow, 2017a:85). Denna studie undersöker och behandlar följande motiv: trend-, sociala-, konsumtionskultur-, etiska- och hälsomotiv. En kvalitativ metod har tillämpats och empirin samlades in genom semistrukturerade intervjuer med vegetarianer i Sverige som
Pupils tend to experience ‘attentional fatigue’ after persistently demanding their attentional system during school hours, resulting in decreased psychological well-being and a lack of attention, along with losses of other cognitive functions. Previous research found natural elements in a school environment to restore pupils’ depleted attentional system. The present study aimed at investigating na
Facing the challenges of climate change and energy depletion, the world needs to deploy more renewable energy to replace fossil fuels. As the largest energy consumer and carbon emitter, China’s sustainable energy transition is particularly important. Owning the vast offshore wind (OW) resources, the Chinese Government has set ambitious goals on OW that provides a reliable and reasonable alternativ
Solanum tuberosum (Potato) is a cool-season, short-day crop that tuberize effectively at temperatures between 15°C-19°C and at a day length of about 12 hours. These environmental requirements pose a moderate challenge to potato cultivar in different region globally. In Northern Europe, summers are characterized by the prolonged daylight and temperature that frequently exceed 19℃. Such conditions c
With the rapid evolution of semiconductor technology and the growing demand for high-performance, low-power System-on-Chip solutions, the design of efficient and scalable on-chip interconnect architectures has become a critical challenge in modern ASIC development. This thesis focuses on design space exploration of replacing multiple ARM CoreLink NIC-400 crossbar-based interconnects with a unified
The recent years spread of misinformation and the rise of post-truth politics have challenged the role of public service media in democratic societies. This thesis explores how the Nordic public service broadcasters – SVT, NRK, DR, RÚV and Yle – position themselves in relation to disinformation, misinformation, and post-truth. Through a qualitative, thematic analysis of their annual reports from 2
Geographical peripheries have long faced marginalization and degradation, enhanced by global trends such as urbanisation. Recently, their revitalization has gained urgency within sustainability discourse, seen as key to achieving global sustainable development. Yet, interventions often focus narrowly on economic recovery, overlooking the social dimension, particularly social cohesion, which is ess
The purpose of this thesis is to enrich our understanding of micro-level internal legal culture by examining how Indonesian legislative lawyers navigate tensions between legal principles and political pressures. The focus is on civil servants within the Coordinating Ministry for Human Development and Cultural Affairs who are tasked with law-making processes, such as drafting, negotiating, and
