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Validation of Risk Scoring Systems in Ursodeoxycholic Acid-Treated Patients With Primary Biliary Cholangitis

INTRODUCTION: Risk stratification based on biochemical variables is a useful tool for monitoring ursodeoxycholic acid (UDCA)-treated patients with primary biliary cholangitis (PBC). Several UDCA response criteria and scoring systems have been proposed for risk prediction in PBC, but these have not been validated in large external cohorts. METHODS: We performed a study on data of 1746 UDCA-treated

Human papillomavirus and Papanicolaou tests to screen for cervical cancer.

Background Screening for cervical cancer based on testing for human papillomavirus (HPV) increases the sensitivity of detection of high-grade (grade 2 or 3) cervical intraepithelial neoplasia, but whether this gain represents overdiagnosis or protection against future high-grade cervical epithelial neoplasia or cervical cancer is unknown. Methods In a population-based screening program in Sweden,

Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 8377 breast cancer patients

Background: Urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) play essential roles in tumor invasion and metastasis. High levels of both uPA and PAT-1 are associated with poor prognosis in breast cancer patients. To confirm the prognostic value of uPA and PAI-1 in primary breast cancer, we reanalyzed individual patient data provided by members of the European Organization for Re

Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure

Background: Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as clonally expanded leukemogenic sequence variations (particularly in DNMT3A, TET2, ASXL1, and JAK2) in asymptomatic individuals, is associated with cardiovascular events, including recurrent heart failure (HF). Objectives: This study sought to evaluate whether CHIP is associated with incident HF. Methods: CHI

Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke) : an international, randomised, double-blind, placebo-controlled, phase 2b trial

Background: Asundexian (Bayer AG, Leverkusen, Germany), an oral small molecule factor XIa (FXIa) inhibitor, might prevent thrombosis without increasing bleeding. Asundexian's effect for secondary prevention of recurrent stroke is unknown. Methods: In this randomised, double-blind, placebo-controlled, phase 2b dose-finding trial (PACIFIC-Stroke), patients with acute (within 48 h) non-cardioembolic

Prostate cancer early detection : Clinical practice guidelines in oncology™

Since the early 1990s, many variants of the tPSA assay have been introduced to increase the sensitivity of screening programs (cancer detection) while maintaining specificity (elimination of unnecessary biopsies). Again, these guidelines recommend ways that individuals and their physicians can use these new techniques rationally for early detection of prostate cancer. These guidelines are not desi

Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease

BACKGROUND: Peripheral artery disease is considered to be a manifestation of systemic atherosclerosis with associated adverse cardiovascular and limb events. Data from previous trials have suggested that patients receiving clopidogrel monotherapy had a lower risk of cardiovascular events than those receiving aspirin. We wanted to compare clopidogrel with ticagrelor, a potent antiplatelet agent, in

The American Business Judgment Rule and Swedish Law - A Comparative Analysis of the American Business Judgment Rule and Its Eventual Counterpart in Swedish Law

Syftet med den här uppsatsen är att undersöka huruvida svenska styrelseledamöter och verkställande direktörer kan förvänta sig att de svenska domstolarna prövar affärsbeslut på ett liknande sätt som de amerikanska domstolarna prövar affärsbeslut. Undersökningen möjliggör en komparativrättslig analys av huruvida det finns något i svensk rätt som liknar den i amerikansk rätt existerande BJR, vilket The purpose of this thesis is to examine whether Swedish directors and CEOs can expect the Swedish courts to review business decisions in a similar way to how the American courts review business decisions. This examination enables a comparative analysis of whether something similar to the American business judgment rule exists in Swedish law, which some Swedish legal scholars claim. The American

Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs) : a multicentre, open-label, randomised, crossover trial

Background: Hypertension is the leading risk factor for cerebral small vessel disease. We aimed to determine whether antihypertensive drug classes differentially affect microvascular function in people with small vessel disease. Methods: We did a multicentre, open-label, randomised crossover trial with blinded endpoint assessment at five specialist centres in Europe. We included participants aged

C4BP(β-)-mediated immunomodulation attenuates inflammation in DSS-induced murine colitis and in myeloid cells from IBD patients

The most recent and promising therapeutic strategies for inflammatory bowel disease (IBD) have engaged biologics targeting single effector components involved in major steps of the immune-inflammatory processes, such as tumor necrosis factor, interleukins or integrins. Nevertheless, these molecules have not yet met expectations regarding efficacy and safety, resulting in a significant percentage o

Interdisciplinary pedagogy in

Interdisciplinary pedagogy in Interdisciplinary pedagogy in higher education Proceedings from Lund University’s Teaching and Learning Conference 2019 EDITORS: JOHANNA BERGQVIST RYDÉN, ANNE JERNECK, JESSIKA LUTH RICHTER & KARIN STEEN LUND UNIVERSITY 1 Interdisciplinary pedagogy in higher education Proceedings from Lund University's Teaching and Learning Conference 2019 Editors: Johanna Bergqvist Ry

https://www.ahu.lu.se/fileadmin/user_upload/ahu/PDF/Proceedings_Interdisciplinary_pedagogy_in_higher_education_Lund_University_2019.pdf - 2026-05-30

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Division of Solid Mechanics Martin Norlander For information please contact: Division of Solid Mechanics, Lund University, Box 118, 221 00 Lund Homepage: www.solid.lth.se CRACK PROPAGATION IN FIXED CALLIPER BRAKE DISCS Master’s Dissertation M artin N o rlan d er C rack p ro p ag atio n in fixed callip er b rake d iscs Department of Mechanical Engineering Solid Mechanics ISRN LUTFD2/TFHF-05/5110-SE

https://www.solid.lth.se/fileadmin/hallfasthetslara/utbildning/examensarbete/TFHF5110.pdf - 2026-05-30

Civilingenjörsutbildning i maskinteknik/maskinteknik med teknisk design utbildningsplan

Civilingenjörsutbildning i maskinteknik/maskinteknik med teknisk design utbildningsplan Sida 1 av 8 Utbildningsplan Civilingenjörsutbildning i maskinteknik/maskinteknik med teknisk design - Programkod: TAMAS/TAMAD - Omfattning: 300 högskolepoäng - Tillträdesnivå: Grundnivå - Beslutsfattare: Programledning M - Utbildningsplanens giltighet: 2025/2026 - Utbildningsplanen fastställd: 2025-02-18 1 Syft

https://www.student.lth.se/fileadmin/lth/student/Utbildningsplaner_2023_och_fram/Grund_svenska/25_26/Utbildningsplan_Civilingenjoersutbildning_i_maskinteknik-maskinteknik_med_teknisk_design_25-26.pdf - 2026-05-30

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Lunds Universitet Historiska institutionen HISA22 Seminarieledare Marie Lindstedt Cronberg VT2015 Amanda L. Westerdahl Att weta hur man skall wara En studie i unga kvinnors dagböcker 1841- 1906 Innehållsförteckning 1 Unga kvinnors dagböcker 1841 – 1906 1 1.1 Syfte & frågeställning 1 1.2 Forskningsläge 2 2 Källor och metod 4 2.1 Källor, källkritik och avgränsningar 4 2.2 Metod 5 3 Historisk bakgrun

https://www.historiska.lu.se/media/utbildning/dokument/kurser/HISA22/20171/Exempeluppsats_Att_weta_hur_man_skall_wara.pdf - 2026-05-31

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LÖNEAVTAL för tjänstemän Avtal tecknat 2023 Giltighetstid: 2023-05-01–2025-04-30 Akademikerförbunden 1 Innehållsförteckning Löner Unionen ............................................................................... 3 Lokalt löneavtal – Unionen .......................................................... 11 Förhandlingsordning vid lönerevision – Unionen ....................... 17 Löner och förhand

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/randstad/dokument/loneavtal-for-tjansteman-2023-2025.pdf - 2026-05-31

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2

Certified reference material for radionuclides in fish flesh sample IAEA-414 (mixed fish from the Irish Sea and North Sea)

A certified reference material (CRM) for radionuclides in fish sample IAEA-414 (mixed fish from the Irish Sea and North Seas) is described and the results of the certification process are presented. Nine radionuclides (K-40, Cs-137, Th-232, U-234, U-235, U-238, Pu-238, Pu239+240 and Am-241) were certified for this material. Information on massic activities with 95% confidence intervals is given fo

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COSM23 Contemporary Chinese Society Literature List Spring Semester 2026 Approved on 18 November 2026 by the education board at the Centre for East and South-East Asian Studies. Introduction In 2026, COSM23 will require students to read 438 pages of book chapters and approximately 1038 pages of journal articles, policy documents, and expert popular discourse. In addition, student will select about

https://www.ht.lu.se/media/utbildning/dokument/kurser/COSM23/20261/COSM23_2026_literature_list.docx - 2026-05-21

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S¿RTRYCK UR VAREN DSBYGDER NORRA ALLBO H EMBYG DSFO RE N I N G t9 53 fa eT )t*ü ,r*Å N,àr*,^ au't n aJ A'/. 6 f 7 ¿ ALVESTÀ 1953 Ero¡ Lrxnsr¡öus SöN¡n, Bonrrvcxrr¡ CARL \ØILHELM VoN SYDO\Ø 1878 - 1952 Av O. LrNosrrN Meddelandet om professor C. \ø. v. Sydows bortgång den 14 mars 1952 mottogs i vida kretsar med känslor av djup saknad och varmt deltagande. Hans vetenskapliga gärning är känd och erkän

https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/images/artiklar_i_pdf-format/Lindsten_O__Carl_Wilhelm_von_Sydow__Saertryck_ur_Vaerendsbygder.pdf - 2026-05-30