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Household composition and the infant fecal microbiome : The INSPIRE study

Objectives: Establishment and development of the infant gastrointestinal microbiome (GIM) varies cross-culturally and is thought to be influenced by factors such as gestational age, birth mode, diet, and antibiotic exposure. However, there is little data as to how the composition of infants' households may play a role, particularly from a cross-cultural perspective. Here, we examined relationships

Validation of Risk Scoring Systems in Ursodeoxycholic Acid-Treated Patients With Primary Biliary Cholangitis

INTRODUCTION: Risk stratification based on biochemical variables is a useful tool for monitoring ursodeoxycholic acid (UDCA)-treated patients with primary biliary cholangitis (PBC). Several UDCA response criteria and scoring systems have been proposed for risk prediction in PBC, but these have not been validated in large external cohorts. METHODS: We performed a study on data of 1746 UDCA-treated

Global diversity and distribution of antibiotic resistance genes in human wastewater treatment systems

Antibiotic resistance poses a significant threat to human health, and wastewater treatment plants (WWTPs) are important reservoirs of antibiotic resistance genes (ARGs). Here, we analyze the antibiotic resistomes of 226 activated sludge samples from 142 WWTPs across six continents, using a consistent pipeline for sample collection, DNA sequencing and analysis. We find that ARGs are diverse and sim

Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP-CARE): A protocol for a randomized clinical trial

Background: In patients resuscitated after cardiac arrest, a higher mean arterial pressure (MAP) may increase cerebral perfusion and attenuate hypoxic brain injury. Here we present the protocol of the mean arterial pressure after cardiac arrest and resuscitation (MAP-CARE) trial aiming to investigate the influence of MAP targets on patient outcomes. Methods: MAP-CARE is one component of the Sedati

Identification of oxidative stress and toll-like receptor 4 signaling as a key pathway of acute lung injury

Multiple lung pathogens such as chemical agents, H5N1 avian flu, or SARS cause high lethality due to acute respiratory distress syndrome. Here we report that Toll-like receptor 4 (TLR4) mutant mice display natural resistance to acid-induced acute lung injury (ALI). We show that TLR4-TRIF-TRAF6 signaling is a key disease pathway that controls the severity of ALI. The oxidized phospholipid (OxPL) Ox

Human papillomavirus and Papanicolaou tests to screen for cervical cancer.

Background Screening for cervical cancer based on testing for human papillomavirus (HPV) increases the sensitivity of detection of high-grade (grade 2 or 3) cervical intraepithelial neoplasia, but whether this gain represents overdiagnosis or protection against future high-grade cervical epithelial neoplasia or cervical cancer is unknown. Methods In a population-based screening program in Sweden,

Evaluation of cognitive subdomains, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D in the European Male Ageing Study

Purpose: Although lower levels of vitamin D have been related to poor cognitive functioning and dementia in older adults, evidence from longitudinal investigations is inconsistent. The objective of this study was to determine whether 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)2D] levels are associated with specified measures of cognitive decline in ageing men. Methods: The

Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease

BACKGROUND: Peripheral artery disease is considered to be a manifestation of systemic atherosclerosis with associated adverse cardiovascular and limb events. Data from previous trials have suggested that patients receiving clopidogrel monotherapy had a lower risk of cardiovascular events than those receiving aspirin. We wanted to compare clopidogrel with ticagrelor, a potent antiplatelet agent, in

The GALAH survey : A new constraint on cosmological lithium and Galactic lithium evolution from warm dwarf stars

Lithium depletion and enrichment in the cosmos is not yet well understood. To help tighten constraints on stellar and Galactic evolution models, we present the largest high-resolution analysis of Li abundances A(Li) to date, with results for over $100\, 000$ GALAH (Galactic Archeology with HERMES) field stars spanning effective temperatures $5900\, \mathrm{K} \lesssim T_{\mathrm{eff}}\lesssim 7000

Omission of doxorubicin from the treatment of stage II-III, intermediate-risk Wilms' tumour (SIOP WT 2001) : an open-label, non-inferiority, randomised controlled trial

BACKGROUND: Before this study started, the standard postoperative chemotherapy regimen for stage II-III Wilms' tumour pretreated with chemotherapy was to include doxorubicin. However, avoidance of doxorubicin-related cardiotoxicity effects is important to improve long-term outcomes for childhood cancers that have excellent prognosis. We aimed to assess whether doxorubicin can be omitted safely fro

CKD : A Call for an Age-Adapted Definition

Current criteria for the diagnosis of CKD in adults include persistent signs of kidney damage, such as increased urine albumin-to-creatinine ratio or a GFR below the threshold of 60 ml/min per 1.73 m2 This threshold has important caveats because it does not separate kidney disease from kidney aging, and therefore does not hold for all ages. In an extensive review of the literature, we found that G

Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure

Background: Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as clonally expanded leukemogenic sequence variations (particularly in DNMT3A, TET2, ASXL1, and JAK2) in asymptomatic individuals, is associated with cardiovascular events, including recurrent heart failure (HF). Objectives: This study sought to evaluate whether CHIP is associated with incident HF. Methods: CHI

Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 8377 breast cancer patients

Background: Urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) play essential roles in tumor invasion and metastasis. High levels of both uPA and PAT-1 are associated with poor prognosis in breast cancer patients. To confirm the prognostic value of uPA and PAI-1 in primary breast cancer, we reanalyzed individual patient data provided by members of the European Organization for Re

The American Business Judgment Rule and Swedish Law - A Comparative Analysis of the American Business Judgment Rule and Its Eventual Counterpart in Swedish Law

Syftet med den här uppsatsen är att undersöka huruvida svenska styrelseledamöter och verkställande direktörer kan förvänta sig att de svenska domstolarna prövar affärsbeslut på ett liknande sätt som de amerikanska domstolarna prövar affärsbeslut. Undersökningen möjliggör en komparativrättslig analys av huruvida det finns något i svensk rätt som liknar den i amerikansk rätt existerande BJR, vilket The purpose of this thesis is to examine whether Swedish directors and CEOs can expect the Swedish courts to review business decisions in a similar way to how the American courts review business decisions. This examination enables a comparative analysis of whether something similar to the American business judgment rule exists in Swedish law, which some Swedish legal scholars claim. The American

Högskoleingenjör i elektroteknik med automation

Högskoleingenjör i elektroteknik med automation | LTH, Lunds Tekniska Högskola Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbp

https://www.lth.se/utbildning/elektroteknik-med-automation/ - 2026-05-28

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KOLLEKTIVAVTAL Tjänstemän Avtal om allmänna villkor, arbetstid och kompetensutveckling 2020-12-01–2023-04-30 Akademikerförbunden har i förhandlingarna företrätts av Akavia. Akavia uppträder under innevarande avtalsperiod som gemensam representant för Akademikerförbunden. Central förhandling, vanligtvis efter lokal förhandling enligt MBL §§ 10-12, begärs hos eller av Akavia oberoende av om berörd p

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/randstad/dokument/2020-2023-bilaga-kollektivavtal-tjansteman.pdf - 2026-05-29

Microsoft Word - katrin och satu formated-14pt.doc

Microsoft Word - katrin och satu formated-14pt.doc Some thoughts on Balto-Finnic passives and impersonals KATRIN HIIETAM (INDEPENDENT SCHOLAR) & SATU MANNINEN (LUND UNIVERSITY) Abstract This working paper focuses on the question of whether the Balto-Finnic impersonal construction can be classified as active or passive. We contrast it with the criteria for impersonal active constructions, listed in

https://www.sol.lu.se/fileadmin/media/forskning/workingpapers/engelska/vol05/Hiietam-Manninen-wp05.pdf - 2026-05-28

Microsoft Word - Final-report-WP1-May01-TVSM_3056.doc

Microsoft Word - Final-report-WP1-May01-TVSM_3056.doc Structural Mechanics Report TV SM -3056 G U STA FSSO N , P. J., and SERRA N O , E G LU ED -IN R O D S FO R TIM B ER STR U C TU R ES - D evelo p m en t o f a C alcu latio n M o d e PER JOHAN GUSTAFSSON and ERIK SERRANO GLUED-IN RODS FOR TIMBER STRUCTURES Development of a Calculation Model Printed by KFS i Lund AB, Lund, Sweden, December 2002. Fo

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm3000/web3056.pdf - 2026-05-28

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KOLLEKTIVAVTAL Tjänstemän Avtal om allmänna villkor, arbetstid och kompetensutveckling 2023-05-01–2025-04-30 Akademikerförbunden har i förhandlingarna företrätts av Akavia. Akavia uppträder under innevarande avtalsperiod som gemensam representant för Akademikerförbunden. Central förhandling, vanligtvis efter lokal förhandling enligt MBL §§ 10-12, begärs hos eller av Akavia oberoende av om berörd p

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/akademikerforbunden-aht/dokument/kollektivavtal/almega-tjansteforetagen-o-medieforetagen_bilaga-a-allm-villk-1-maj-2023---30-april-2025---i-lydelse-av-2023-05-01.pdf - 2026-05-29