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Insulin-like growth factor-1 (IGF-1) is essential for normal brain development and regulates essential processes of vascular maturation and stabilization. Importantly, preterm birth is associated with reduced serum levels of IGF-1 as compared to in utero levels. Using a preterm rabbit pup model, we investigated the uptake of systemic recombinant human (rh) IGF-1 in complex with its main binding pr

The development of the microbiome from infancy to childhood is dependent on a range of factors, with microbial–immune crosstalk during this time thought to be involved in the pathobiology of later life diseases1–9 such as persistent islet autoimmunity and type 1 diabetes10–12. However, to our knowledge, no studies have performed extensive characterization of the microbiome in early life in a large

BACKGROUND AND OBJECTIVES: Under the ISBT, the Working Party (WP) for Red Cell Immunogenetics and Blood Group Terminology is charged with ratifying blood group systems, antigens and alleles. This report presents the outcomes from four WP business meetings, one located in Basel in 2019 and three held as virtual meetings during the COVID-19 pandemic in 2020 and 2021.MATERIALS AND METHODS: As in prev

Response determinants to immunotherapy in metastatic pancreatic ductal adenocarcinoma (mPDAC) remain unclear, limiting treatment advancements. We report a single-arm phase 1b/2 study (OPTIMIZE-1) evaluating the safety and efficacy of the cluster of differentiation 40 (CD40) agonist mitazalimab combined with modified FOLFIRINOX (mFOLFIRINOX), in chemotherapy-naive patients with mPDAC. Patients rece

BACKGROUND: Alzheimer's disease pathology can be accurately identified with blood biomarkers (core 1 biomarkers), including plasma p-tau217 tests. Biomarkers that change longitudinally after diagnosis (core 2 biomarkers) can increase confidence that Alzheimer's disease pathology is contributing to cognitive symptoms. Plasma eMTBR-tau243 reflects tau tangle pathology and is a promising core 2 bioma

Mechanical Engineering Sciences | LTH, Faculty of Engineering Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These

https://www.lth.se/english/research/department-descriptions/mechanical-engineering/ - 2026-05-18

An extraordinary, ordinary day Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any perso

https://www.lth.se/english/article/an-extraordinary-ordinary-day/ - 2026-05-18

Information for new employees | LTH, Faculty of Engineering Skip to main content We use cookies and other tracking technologies to improve the user experience on our website, to show you personalised content and targeted ads, and to analyse our website traffic. Cookie Policy . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These c

https://www.lth.se/english/work/information-for-new-employees/ - 2026-05-18

Call for Applications of Researchers in Southern Africa - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreac

https://rwi.lu.se/news/call-for-applications-of-researchers-in-southern-africa/ - 2026-05-18

Master’s Dissertation Structural Mechanics DAVID BJURHEDE and MATS HARRYSON Report TV SM -5178 D A V ID BJU RH ED E and M A TS H A RRY SO N A CO M PA RA TIV E STU D Y O F CO U PLED A N D U N CO U PLED A N A LY SIS M ETH O D S FO R TH ERM O H Y D RA U LIC LO A D S IN PIPE SY STEM S A COMPARATIVE STUDY OF COUPLED AND UNCOUPLED ANALYSIS METHODS FOR THERMOHYDRAULIC LOADS IN PIPE SYSTEMS Detta är en to

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5178.pdf - 2026-05-18

How States Better Can Handle Pandemics in the Future   - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach

https://rwi.lu.se/2021/06/08/how-states-better-can-handle-pandemics-in-the-future/ - 2026-05-18

MAPPINGMAPPING HOW TO SUPPORT HUMAN RIGHTS HOW TO SUPPORT HUMAN RIGHTS EDUCATION AND RESEARCH IN EDUCATION AND RESEARCH IN UKRAINIAN LAW SCHOOLSUKRAINIAN LAW SCHOOLS Report of the pilot study Arsen Markiv 2023 © 2023 Raoul Wallenberg Institute of Human Rights and Humanitarian Law First Edition (2023) ISBN 978-91-86910-53-2 Author: Arsen Markiv The author would like to thank Morten Koch Andersen, Z

https://rwi.lu.se/wp-content/uploads/2023/03/RWI-Mapping-Study-Ukrainian-Law-Schools-2023.pdf - 2026-05-18

Concept Note “Human Rights Research in Armenia: Current and Emerging Issues” 4th International Conference organised by the Raoul Wallenberg Institute of Human Rights and Humanitarian Law, in Yerevan, November 13-14, 2026 The Raoul Wallenberg Institute of Human Rights and Humanitarian Law (hereinafter “RWI”), Lund, Sweden is pleased to announce the fourth international conference "Human Rights Rese

https://rwi.lu.se/wp-content/uploads/2026/04/Concept-Note-for-the-Conference-_RWI_2026_EN.docx - 2026-05-18

PowerPoint-presentation 2014-03-31 1 Föreläsning 10 Utilitarismen Den klassiska utilitarismen 2 Det finns flera olika former av utilitarism. Den klassiska versionen kan sammanfattas i tre påståenden: 1. En handling är rätt omm den leder till goda konsekvenser (fel omm den leder till dåliga konsekvenser) 2. En konsekvens är god omm den innebär en större mängd total lycka i universum (och dålig omm

https://www.fil.lu.se/media/utbildning/dokument/kurser/FPRA11/20141/Bergstrm_Rachels_10_utilitarism_.pdf - 2026-05-19

Popular Abstract in Swedish Sammanfattning Den här avhandlingen handlar om gränsskiktet mellan nanoteknologi och cellbiologi, om hur celler och nanostrukturer påverkar varandra, och om hur man kan använda nanopinnar för att studera celler. Å ena sidan vill man kunna mäta egenskaper hos cellerna, det vill säga låta cellerna påverka pinnarna, å andra sidan vill man kunna styra cellerna – låta pinnarThis study explores the interaction between living biological cells and semiconductor nanowires. Biological cells are highly complex and dynamic entities, every one of them with individual characteristics and a high degree of internal and external communication. They respond to and affect their external environment with a huge web of fine-tuned control systems. Traditional biochemical tools for

The costimulatory receptor 4-1BB is expressed on activated immune cells, including activated T cells. Antibodies targeting 4-1BB enhance the proliferation and survival of antigen-stimulated T cells in vitro and promote CD8 T cell-dependent anti-tumor immunity in pre-clinical cancer models. We found that T regulatory (Treg) cells infiltrating human or murine tumors expressed high amounts of 4-1BB.

Individuals with cancer may be at high risk for coronavirus disease 2019 (COVID-19) and adverse outcomes. However, evidence from large population-based studies examining whether cancer and cancer-related therapy exacerbates the risk of COVID-19 infection is still limited. Data were collected from the COVID Symptom Study smartphone application since March 29 through May 8, 2020. Among 23,266 partic

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING Halsbränna och sura uppstötningar är vanliga åkommor i den svenska befolkningen där upp till 20 procent av de tillfrågade uppger sig ha besvär av dessa symtom varje vecka. Både halsbränna och sura uppstötningar anses vara symtom på att magsäcksinnehåll flödar tillbaka upp genom övre magmunnen till matstrupen sk gastroesofageal reflux.This thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. A statement based on the evidence that reflux induced complications as esophagitis and

Popular Abstract in Swedish Transplantation av lungor är ett relativt nytt behandlingsalternativ vid svår lung-sjukdom. Den första lungtransplantationen på människa gjordes 1963. Patienten dog efter 18 dagar i njursvikt. Mellan 1963 och 1980 gjordes ca 40 lungtransplantationer i världen med nedslående resultat. Medianöverlevnaden var enbart 8,5 dagar och den patient som levde längst levde bara 6 mDuring the past 15 years lung transplantation has been established as a therapeutic option for patients with end-stage pulmonary disease. The results have improved over time and some transplantation centers now show 1-year survival rates above 80%. The number of donors has remained relatively constant during later years but the demand is increasing resulting in longer waiting times and an increasi

Building a detailed understanding of the structure function relationship is a crucial step in the optimization of molecular photocatalysts employed in water splitting schemes. The optically dark nature of their active sites usually prevents a complete mapping of the photoinduced dynamics. In this work, transient X-ray absorption spectroscopy highlights the electronic and geometric changes that aff