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Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression

Lymphatic vessels (LVs) play critical roles in the maintenance of fluid homeostasis and in pathological conditions, including cancer metastasis. Although mutations in ALK1, a member of the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) receptor family, have been linked to hereditary hemorrhagic telangiectasia, a human vascular disease, the roles of activin receptor-like kin

Riktlinjer gällande examina och utbildning på grundnivå och avancerad nivå vid Lunds universitet. Be

Riktlinjer gällande examina och utbildning på grundnivå och avancerad nivå vid Lunds universitet Sida 1 av 1 FÖRSÄTTSSIDA STYRDOKUMENT Riktlinjer gällande examina och utbildning på grundnivå och avancerad nivå vid Lunds universitet Typ av styrdokument: Riktlinjer Definition av typen av styrdokument: Riktlinjer fastställer hur någon ska eller bör handla inom det område riktlinjerna omfattar. En ska

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2025-10/riktlinjer-gallande-examina-och-utbildning-pa-grundniva-och-avancerad-niva-vid-lunds-universitet.pdf - 2026-05-17

Identification of Adaptation in Human Postural Control using GARCH Models

Human postural dynamics was investigated in twelve normal subjects by means of a force platform recording body sway induced by bipolar transmastoid galvanic stimulation of the vestibular nerve and labyrinth. We modeled the stabilizing forces actuated by the feet as resulting from complex muscular activity subject to feedback of body velocity and position. Time series analysis demonstrated that a t

Molecular characterization of an outbreak of respiratory syncytial virus (subgroup A) in Havana, Cuba, by monoclonal antibodies and restriction mapping (N gene)

Twenty-one respiratory syncytial virus (RSV) strains isolated from one outbreak in Havana, Cuba (1994 to 1995), were analyzed to determine their relatedness. All isolated strains were classified as subgroup A by monoclonal antibodies. Of 21 RSV strains examined, 20 were classified as having restriction pattern NP4 and only 1 was classified as having restriction pattern NP5.

Pharyngeal reflux after gastric pull-up esophagectomy with neck and chest anastomoses

OBJECTIVE: Pharyngeal reflux after a gastric pull-up esophagectomy may cause aspiration. This study evaluates acid exposure to the esophageal remnant and to the pharynx after gastric pull-up esophagectomy and evaluates the impact of additional dissection of the esophagus that is necessary for neck anastomoses versus no neck exploration and proximal chest anastomoses.METHODS: Forty-seven patients h

Investigating the state of play of geobim across Europe

In both the Geographic Information (Geo) and Building Information Modelling (BIM) domains, it is widely acknowledged that the integration of data from both domains is beneficial and a crucial step in facing the multi-disciplinary challenges of our built environment. The result of this integration - which can broadly be termed GeoBIM -could answer questions such as identifying an appropriate Heatin

Isolation and characterization of a 14-kDa albumin-binding fragment of streptococcal protein G

Protein G, a streptococcal cell wall protein, has separate binding sites for human albumin and IgG. Streptococci expressing protein G were treated with the bacteriolytic agent mutanolysin. Several IgG- and human serum albumin (HSA)-binding peptides were identified in the material thus solubilized and one of these, a 14-kDa peptide, was found to bind HSA but not IgG in Western blot experiments. Thi

CARIBIC observations of gaseous mercury in the upper troposphere and lower stratosphere

A unique set of gaseous mercury measurements in the upper troposphere and lower stratosphere (UT/LS) has been obtained during the monthly CARIBIC (www.caribic-atmospheric.com) flights since May 2005. The passenger Airbus 340-600 of Lufthansa covered routes to the Far East, North America, India, and the southern hemisphere. The accompanying measurements of CO, O3, NOy, H2O, aerosols, halocarbons, h

A cell topography-based mechanism for ligand discrimination by the T cell receptor

The T cell receptor (TCR) initiates the elimination of pathogens and tumors by T cells. To avoid damage to the host, the receptor must be capable of discriminating between wild-type and mutated self and nonself peptide ligands presented by host cells. Exactly how the TCR does this is unknown. In resting T cells, the TCR is largely unphosphorylated due to the dominance of phosphatases over the kina

A new approach to materials in Product Design education : A shift from technical properties towards sensorial characteristics

This study evaluates a new pedagogic approach implemented in material courses for product design students at bachelor level education. Material education within the field of design education at technical faculties has, in general, a strong technical focus, e.g. selecting materials with predominant focus on engineering properties of materials. Product design education at a bachelor level need to of

Acute respiratory distress syndrome due to Cryptococcus albidus pneumonia : case report and review of the literature

Although cryptococcal infections due to Cryptococcus neoformans are frequently reported in the immunosuppressed patients, infections related to other Cryptococcus spp. are rarely reported. We are reporting a case of pulmonary infection and ARDS due to C. albidus in a patient receiving immunosuppressive therapy because of Still's disease. The diagnosis was made by tissue biopsy and culture. The pat

Fundamental effective temperature measurements for eclipsing binary stars-III. SPIRou near-infrared spectroscopy and CHEOPS photometry of the benchmark G0V star EBLM J0113+31

EBLM J0113+31 is a moderately bright (V = 10.1), metal-poor ([Fe/H] ≈-0.3) G0V star with a much fainter M dwarf companion on a wide, eccentric orbit (= 14.3 d). We have used near-infrared spectroscopy obtained with the SPIRou spectrograph to measure the semi-amplitude of the M dwarf's spectroscopic orbit, and high-precision photometry of the eclipse and transit from the CHEOPS and TESS space missi

Immunity to Rotavirus infection across ages

Rotavirus (RV) is a double-stranded RNA virus that mainly affects young children under the age of five years. It is one of the leading causes of dehydrating gastroenteritis. Every year, about 200,000 child deaths occur due to RVinfection. Vaccines exist and are in use worldwide. However, these vaccines' efficacy is relatively low in countries where deaths due to the virus are high.The aim of the w

Predicting the survival of patients with peritoneal carcinomatosis of colorectal origin treated by aggressive cytoreduction and hyperthermic intraperitoneal chemotherapy

BACKGROUND: Peritoneal carcinomatosis in the absence of distant metastasis occurs in approximately 8 per cent of patients with colorectal cancer. Cytoreduction followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a new treatment option. Patient selection is crucial to outcome.METHODS: Cytoreduction followed by HIPEC was performed in 102 patients with peritoneal carcinomatosis. The foll

IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage

Conventional dendritic cells (cDCs) consist of two major functionally and phenotypically distinct subsets, cDC1 and cDC2, whose development is dependent on distinct sets of transcription factors. Interferon regulatory factor 8 (IRF8) is required at multiple stages of cDC1 development, but its role in committed cDC1 remains unclear. Here, we used Xcr1-cre to delete Irf8 in committed cDC1 and demons

Consumption of ultraprocessed food and development of chronic kidney disease : the Tianjin Chronic Low-Grade Systemic Inflammation and Health and UK Biobank Cohort Studies

BackgroundMany ultraprocessed food (UPF)-derived by-products may play a role in the development of chronic kidney disease (CKD). Although several studies have assessed the association of UPFs with kidney function decline or CKD in various countries, no evidence has been shown in China and the United Kingdom.ObjectivesThis study aims to evaluate the association between UPF consumption and risk of C

A Preliminary Checklist for Capturing Baseline Situations in Studying the Impacts of Agile Practices Introduction

To assess the benefits of introducing Agile practices, it is important to get a clear understanding of the baseline situation, i.e. the situation before their introduction. Without a clear baseline, we cannot properly assess the extent of impacts, both positive and negative, of introducing Agile practices. This paper provides a preliminary guideline to help researchers in capturing and reporting b

APOGEE Data Releases 13 and 14 : Stellar Parameter and Abundance Comparisons with Independent Analyses

Data from the SDSS-IV/Apache Point Observatory Galactic Evolution Experiment (APOGEE-2) have been released as part of SDSS Data Releases 13 (DR13) and 14 (DR14). These include high-resolution H-band spectra, radial velocities, and derived stellar parameters and abundances. DR13, released in 2016 August, contained APOGEE data for roughly 150,000 stars, and DR14, released in 2017 August, added about

New strategies for the conduct of clinical trials in paediatric Pulmonary Arterial Hypertension (PAH): Outcome of a multi-stakeholder meeting with patients, academia, industry and regulators held at EMA on Monday 12th June 2017

Aims: Drug development for paediatric pulmonary arterial hypertension (PAH) ispressingly needed. Experts from the US Food and Drug Administration, EuropeanMedicines Agency, Health Canada, key opinion leaders, academia, patients, and industry representatives held a workshop on 12th June 2017 dedicated to addressing challenges and unmet needs. This report summarises the approaches proposed during th

Association between added sugar intake and mortality is nonlinear and dependent on sugar source in 2 Swedish population-based prospective cohorts

Background: Although sugar consumption has been associated with several risk factors for cardiometabolic diseases, evidence for harmful long-term effects is lacking. In addition, most studies have focused on sugar-sweetened beverages (SSBs), not sugar per se. Objective: The aim of this study was to examine the associations between added and free sugar intake, intake of different sugar sources, a