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Heparin-induced thrombocytopenia (HIT, type II) is an immune-mediated disorder due to antibodies formed against heparin platelet factor 4 complexes, usually appearing at days 5 to 14 after initiation of heparin. It is important to recognize HIT because heparin prophylaxis or treatment paradoxically associates with new venous and/or arterial thrombosis. Early clinical suspicion and diagnosis togeth
Lifestyle behaviors and genetic variation have clear and distinguishable effects on obesity risk; however, the pattern of disease occurrence within and between populations that differ in their genetic and environmental underpinnings suggests obesity is caused in part by the interaction between adverse lifestyle behaviors and the genetic risk profile of an individual. This thesis aims to investigat
The primary goal of this study was to examine whether changes in the temporal distance of a moral dilemma affect how it is perceived and subsequently resolved. Based on Construal Level Theory (Trope & Liberman, 2003), it was predicted that the relative weight of abstract justice features should increase and the relative weight of concrete care features should decrease with temporal distance. T
Inclusive innovation is seen as a means to counteract the issue of growing global inequality. Particularly universities and private businesses are engaged with its promotion. However, the concept of inclusive innovation has deficiencies concerning the operationalisation and measurement. In default of extensive primary data, a set of a hundred and two inclusive innovations has been gathered from tw
This study analyzes the relationship between education, antibiotic consumption and antibiotic resistance in the European ambulatory care. For this purpose, a panel data analysis is conducted on an aggregate level in a sample of 30 countries in the European Economic Area between 2000 and 2014. The main variable of interest is the level of high education, expressed as the proportion of the total pop
Sexual violence is ubiquitous. It occurs everywhere. Due to the very nature of sex crimes, however, victim-survivors from sexual violence are much more vulnerable from ‘secondary victimization’ which is also known as ‘post crime victimization’ or ‘double victimization.’ Given that people get common knowledge on human rights issues from newspapers, in particular online articles today, I focused on
Motivation: 3D brain organoids are biological models of human brain development from which a rich body of data can be extracted that allows for insights about neuronal dynamics. Several tools, such as fluorescence calcium imaging microscopy and electrophysiological recordings are being used to assess how 3D brain organoid dynamics recapitulate what is known from the human brain. In-silico automate
In 2020, breast cancer became the most common type of cancer worldwide. While treatment and technology have radically improved, leading to high 5-year survival, the long-term survival of breast cancer is still poor. Gene expression profiling of patients is an important source of information for outcome prediction. The Sweden Cancerome Analysis Network-Breast (SCAN-B) was initiated in 2009 and prov
Addressing climate change will entail groups of people working together to bring about changes in fundamental societal structures. This research investigates how the members of three collective initiatives on climate change in Sweden envision the process of change, based on their understandings of structures and agency. Margaret Archer and Pierre Bourdieu’s theorisations on this matter serve as an
The metabolism of pyruvate in the cell is abnormally regulated in several human diseases, such as type-II diabetes, cancer and neurodegenerative disorders, in which the human mitochondrial pyruvate carrier (HuMPC) sits at a pivotal point. It transports pyruvate across the inner mitochondrial membrane and consists of two proteins, MPC1 and MPC2, and is a potential drug target against these diseases
Tidigare forskning indikerar att personlighet och personliga värderingar är relaterade konstrukt med medelstora korrelationer. Dock har få studier undersökt relationer på fasettnivå. Varje ’Big Five’ faktor innehåller en lägre nivå med ett flertal fasetter vilka tros representera faktorns specifika innehåll. Eftersom de fem faktorerna i ’Big Five’ representerar ett medelvärde av sina respektive faPrevious research suggests that personality and personal values are related constructs with sizeable correlations. However, few previous studies have examined trait-value relations at facet level. Each Big Five trait domain contains several lower-order facets thought to represent the specific contents of the higher-order traits. As a Big Five trait represents an average of its facets, the Big Five
This thesis explores how the city of Malmö plans for the housing provision from a sustainability perspective by studying social and environmental sustainability in the urban development process with a focus on housing. The study is a qualitative case study and interviews with employees working in the municipality and a document study have been conducted. The results have been analysed through the
The study of minimal surfaces has a long history, due to the important applications. Given a fixed boundary, one wants to minimise the surface area: this can be used, for example, to minimise the area of the roof of a building. Similarly, looking for constant mean curvature (CMC) provides us with many interesting applications in physics – one of the easiest examples are soap bubbles. In this work
The decentralization of fiscal responsibilities in China has strengthened economic development and enhanced local public management. However, due to fiscal competition, local governments that are fiscally constrained tend to neglect environmental standards in favour of economic growth. This study researches how outcomes of fiscal federalism in China, measured by budgetary ratios of gross regional
Many bird species living in farmland habitats have suffered severe declines in recent years. This fact has been object to many studies and the reasons for the decline are many, but it all comes down to effects of our shift to a more effective farmland management. We use the land in a more intense way than before. The use of chemicals has effect both on the birds and their food resources. A more ho
Given the widespread underemployment in Africa, on-the-job search represents a key channel through which individuals seek better employment oppor- tunities that value their skills and competences. However, empirical research on the determinants of on-the-job search has almost exclusively been conducted in advanced economies. The study aims to identify the determinants of on-the-job search among di
Investigating the discourse around development aid and cooperation yields insights into development policy choices and their public legitimisation and justification because of the recognised opinion-forming effect that public information, especially media, has on the public. Hence, public development discourse informs and shapes how ordinary people make sense of development issues and the perceive
The spread of invasive alien species poses great risks for biodiversity, human health and economies. Impatiens glandulifera, an invasive alien plant which has been listed in The European list of Invasive Alien Species of Union concern, is widely spread in Sweden. Multiple studies have been made regarding the plant’s characteristics, spread and impacts on invaded areas. The purpose of this study i
This paper explores how electrical appliances, together with the idea of attaining energy access in the near future, create hope in a northern village in Malawi. Even though less than one per cent of the rural population has energy access, some of these locals already own solar systems. Nevertheless, their solar equipment is not powerful enough to generate the large amounts of energy required to r
