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Group A Streptococcus (GAS)causes infections ranging from mild sore throats to severe invasive disease; however, no licensed vaccine is currently available. In this thesis, the author leverages streptolysin O (SLO), an important GAS protein and therapeutic/vaccine target, as a model system to develop a multimodal protein mass spectrometry(MS) strategy. Through an integrated approach of MS-based pr

186 countries have ratified The Convention on Rights of People with Disabilities (CRPD) since 2006. Sweden ratified the CRPD in 2008, Denmark in 2009, and Norway in 2013. In the context of the United Nations, the concept of Universal Design (UD) introduced in the CRPD is new. Previously, accessibility was the dominant concept. By ratifying the CRPD, these three countries have agreed to initiate or

We developed an algorithm for the early screening of autism spectrum disorder using baby cry sound. We collected the sound using a smartphone application to record it in their daily life. We employed the Japanese version of the Modified Checklist for Autism in Toddlers (M-CHAT) for the evaluation of the autism spectrum. We built a prediction model for binary classification using least absolute shr

Accessible housing plays a crucial role in supporting aging in place, yet Japan lacks adequate tools for assessing housing accessibility among older adults. This study describes the process of translating and adapting the environmental component checklist of the Swedish Housing Enabler instrument for valid use in Japan. During translation to the Japanese language, technical terms and specification

Urban densification is a way of accommodating population growth. Land adjacent to railways is used for constructing residences and other buildings, and new tramway systems are planned. Under these circumstances, nearby buildings will be exposed to vibrations and noise that may become a nuisance for the residents. It is necessary, even at an early stage of planning, to assess the extent of the vibr

Objectives This study investigated the association between cancer of the extrahepatic biliary tract and exposure to endocrine-disrupting compounds. Methods Altogether 183 men with histologically confirmed carcinoma of the extrahepatic biliary tract and 1938 matched controls were interviewed between 1995 and 1997 in the frame of an international multicenter case-control study in six European countr

Multi-talker noise impedes children's speech processing and may affect children listening to their second language more than children listening to their first language. Evidence suggests that multi-talker noise also may impede children's memory retention and learning. A total of 80 culturally and linguistically diverse children aged 7 to 9 years listened to narratives in two listening conditions:

We propose a simple, general and computationally efficient algorithm for maximum likelihood estima- tion (MLE) of parameters in diffusion and jump-diffusion processes. This is conducted within a Monte Carlo EM-algorithm, where the smoothing distribution is computed using resampling. The results are encouraging as we can approximate the MLE well for the models studied when using simulated data. We

REPORT TITLE 1 Report of the RWI Afghanistan Programme Kobra Moradi Raoul Wallenberg Institute of Human Rights and Humanitarian Law “Throwing Dust in Our Eyes”: Nomadic-Sedentary Land Conflict in Hazarajat under the Taliban and Its Human Rights Impacts 0 The copyright of the Raoul Wallenberg Institute of Human Rights and Humanitarian Law (RWI) Illustrations included in the publication are the work

https://rwi.lu.se/wp-content/uploads/2025/05/Kobra-Moradi-2025-Throwing-Dust-in-Our-Eyes.pdf - 2026-06-12

Historiskt sett har människor gjort invändningar grundade på tankefrihet, samvetsfrihet och religionsfrihet i förhållande till obligatorisk värnpliktstjänstgöring. Denna samvetsvägran inom militären är en erkänd rätt i nationella, regionala och internationella människorättsinstrument. I den Europeiska konventionen om skydd för de mänskliga rättigheterna och de grundläggande friheterna är denna rätHistorically, objections based on the freedom of thought, conscience and religion have been invoked in relation to compulsory military service. These conscientious objections are protected by national, regional and international human rights instruments. In the European Convention on Human Rights this right is grounded in Article 9 on the freedom of thought, conscience and religion. In Europe, the

The first aim of this study is to investigate what it takes for a nonprofit association (NPA) to become a legal entity, specifically regarding requirements addressing decision-making organs within the NPA’s organization. Secondly, since within the legal framework of associations there exist general principles of law, this study also explores which general principles of law are applicable to a gene

In the ongoing library debate part of the focus has been on youth in libraries and how many libraries find them to be a challenging group to work with due to some occurring disturbances. In some cases the youth sections start to lean towards being youth recreation centers. Youth need somewhere to be that isn’t home or school and since there aren’t many open, free of cost public spaces, and many ci

Det är statens suveräna rätt att reglera utlänningars närvaro inom dess territorium. Denna rätt är däremot inte utan begränsningar. Artikel 1 i protokoll nr. 7 till Europeiska konventionen om skydd för de mänskliga rättigheterna säkerställer rättssäkerhetsgarantier i samband med utvisningen av utlänningar. Dessa rättssäkerhetsgarantier måste tillgodoses vid utvisningsförfarandet i de medlemsstaterIt is the sovereign prerogative of the state to regulate the presence of aliens within its territory. This right, however, is not without limits. Article 1 of Protocol No. 7 to the European Convention on Human Rights ensures procedural safeguards relating to the expulsion of aliens. These safeguards must be considered in expulsion proceedings by those Member States having ratified the protocol.

Packaging innovation is a strategic and valuable tool yet underexplored in business and extended value chains. Demographic changes, as population aging, and the increase of healthcare costs pose challenges and opportunities for the pharmaceutical industry, where packaging innovation offers new opportunities to provide patients with better solutions. This study employs a multi-stakeholder perspecti

The αβ T-cell coreceptor CD4 enhances immune responses more than 1 million-fold in some assays, and yet the affinity of CD4 for its ligand, peptide-major histocompatibility class II (pMHC II) on antigen-presenting cells, is so weak that it was previously unquantifiable. Here, we report that a soluble form of CD4 failed to bind detectably to pMHC II in surface plasmon resonance-based assays, establ

Current paper presents the results of investigating of multifunctional Ti-Si-N coatings. Ti-Si-N coatings have been deposited using CAVD method with the aim of studying their chemical, physical, structural and mechanical properties. Coatings of Ti-Si-N were modified by high-intensity ion implantation using copper ions with dose D = 2 × 1017 ions/cm2 and energy E = 60 keV. The results demonstrated

Background: The P1 antigen was first described in 1927 but not categorized with the Pk antigen in the P1PK histo-blood group system until 2010. Individuals of P1 phenotype have both the Pk and P1 antigens on their red blood cell (RBC) surface, while P2 individuals lack P1 and have lower amounts of Pk. Like in the ABO system, the antigens are carbohydrate epitopes built up stepwise by glycosyltrans

Inflammation is reported in post-traumatic stress disorder (PTSD). Few studies have investigated circulating blood cells that may contribute to inflammation. We assessed circulating platelets, white blood cells (WBC) and red blood cells (RBC) in PTSD and assessed their relationship to inflammation and symptom severity. One-hundred and sixty-three male combat-exposed veterans (82 PTSD, 81 non-PTSD)