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Chemokines constitute a large family of low-molecular-weight proteins (∼10 kDa in size), recognized primarily for their role in directing leukocyte migration under both homeostatic and inflammatory settings. The chemokine CCL25 displays a unique and highly restricted expression pattern compared with other chemokine family members. In the steady state, CCL25 is expressed at high levels primarily in
Consumer goods manufacturers aiming to reduce the environmental impact associated with their products commonly pursue incremental change strategies, but more radical approaches may be required if we are to address the challenges of sustainable consumption. One strategy to realize step change reductions is to prepare a portfolio of innovations providing different levels of impact reduction in excha
Objectives: Maintaining good cognitive function with aging may be aided by technology such as computers, tablets, and their applications. Little research so far has investigated whether internet use helps to maintain cognitive function over time.Design: Two population-based studies with a longitudinal design from 2001/2003 (T1) to 2007/2010 (T2).Setting: Sweden and the Netherlands.Participants: Ol
AbstractShiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli (EHEC). EHEC strains cause gastrointestinal infection and release Stx that can gain access to the circulation. Patients may develop hemolytic uremic syndrome with extensive kidney damage. In the first paper we investigated if blood cell-derived microvesicles released during EHEC infection contain Stx. Toxi
With the construction sector being responsible for about 40% of the energy and material use, the sector has a great responsibility for lowering the consumption if we are to succeed in our global pursuit for the green transition. However, buildings must still comply with the demands of users. For long-span, openspace lightweight, multi-storey buildings, this provides a potential risk related to ann
As part of the green transition, a current trend in the construction sector is to utilize more wood and lightweight composites, aiming at a reduction of the embodied energy in buildings. At the same time, with a focus on circularity and reuse, large-span structures are preferable, since they provide more flexibility for future uses of the building. The mix of large spans and lightweight structures
Timber buildings are intrinsically lightweight and hence can be susceptible to low-frequency vibrations and structure-borne noise. So, within the development of technical solutions for mitigating unwanted vibrations and noise, accurate and computationally efficient numerical models are considered to be of great value. Such models should take into account all physical phenomena that are relevant fo
We present an upgraded version of the mocca code for the study of dynamical evolution of globular clusters (GCs) and its first application to the study of evolution of multiple stellar populations. We explore initial conditions spanning different structural parameters for the first (FG) and second generation of stars (SG) and we analyse their effect on the binary dynamics and survival. Here, we fo
Presents a new view of the standard of living development in Sweden during the agricultural revolution, using evidence on the ability to overcome short-term economic stress. The results corroborate previous findings, based on a variety of indicators, that standard of living in Sweden increased for most people after the mid-nineteenth century, but also support a more negative view of the immediate
Lymphoid organ hypertrophy is a characteristic feature of acute infection and is considered to enable efficient induction of adaptive immune responses. Accordingly, oral infection with rotavirus induced a robust increase in cellularity in the mesenteric LNs, whose kinetics correlated with viral load and was caused by halted lymphocyte egress and increased recruitment of cells without altered cellu
This chapter examines changes to safe third country law and practice from 2010 to 2020 focusing on Europe, Australia, North, and South America. These developments have received little academic attention, particularly from a comparative perspective. We argue that in all four regions there has been a significant weakening of protection standards in the safe third country context, with the thresholds
Vacuum cleaner motor is an air cooled single-phase induction motor with impeller. Its compact design can result in more than 2 kW of input power per 1 kg of mass. It can operate only if an air flow is cooling the motor; otherwise it is overheated and destroyed. A large production volume of a vacuum cleaner motor classifies it as a mass production product. In the past its development has been mostl
The characteristics of the stellar populations in the Galactic bulge info and constrain the Milky Way's foation and evolution. The metal-poor population is particularly important in light of cosmological silations, which predict that some of the oldest stars in the Galaxy now reside in its centre. The metal-poor bulge appears to consist of ltiple stellar populations that require dynamical analyses
Research on telomeres in the fields of ecology and evolution has been rapidly expanding over the last two decades. This has resulted in the formulation of a multitude of, often name-given, hypotheses related to the associations between telomeres and life-history traits or fitness-facilitating processes (and the mechanisms underlying them). However, the differences (or similarities) between the var
Event detection and classification algorithms are resilient towards aggressive resource-aware optimisations. In this paper, we leverage this characteristic in the context of smart health monitoring systems. In more detail, we study the attainable benefits resulting from tailoring Support Vector Machine (SVM) inference engines devoted to the detection of epileptic seizures from ECG-derived features
The Swedish pulp and paper industry (PPI) accounts for almost 50 percent of industrial final energy use. It is an energy-intensive industry and process optimization is seen as prerequisite to compete on the global market. This alone should motivate company boards and on-site organisations to put energy management high on the agenda. Definitely, from time to time, energy issues (e.g. fuel shifts, s
This study offers a method for empirically testing theories operationalized in the form of multivariate statistical models. An innovation of the method is that it distinguishes testing into three separate forms, “effect testing,” “prediction testing,” and “theory testing,”where statistical significance plays a separate role in each one. In another innovation, the researcher specifies not only his
