Search results

Introduction Many kinds of footwear are used for various purposes in the workplace in Japan. Careful selection of footwear is needed to protect workers from coldness and to keep the performance of workers in cold workplace where employees have to work under -20℃. On the other hand, safety boots with high heat conductivity from foot to outside are needed for the workers in hot environments. But the

The base (BOP) and the top (TOP) of the world income pyramid represent the people living in poverty and the people from developed countries, respectively. In the approach of business development combined with poverty alleviation, the design of products for the BOP plays an important role. There is an urgent need to develop an understanding of the process of designing products for the BOP. Requirem

In recent years, a number of planetary systems have been proposed to orbit-evolved binary star systems. The presence of planets is invoked to explain observed variations in the timing of mutual eclipses between the primary and secondary components of the binary star system. The planets recently proposed orbiting the cataclysmic variable system QS Virginis are the latest in this ongoing series of `

Popular Abstract in Swedish I cellen styrs allt av biomolekylernas förmåga till igenkänning och växelverkan med varandra. Molekylernas speciella egenskaper bygger upp kroppens alla komplicerade funktioner, till exempel immunförsvar, celldelning och muskelarbete. Interaktionerna mellan biomolekylerna kan vara av olika karaktär; de beskrivs som starka eller svaga (affinitet), långsamma eller snabba Molecular recognition and interaction is fundamental for the function of biological systems. The properties of the interacting biomolecules dictate the type of forces involved and the strength and dynamics of the interaction. Many interactions are very strong whereas others exhibit weak affinity. Typically, weak interactions work in concert to trigger a biological response. The advantage with thi

Popular Abstract in Swedish Vår läkemedelsanvändning har eskalerat de senaste två årtionden och vi har kunnat behandla, bota och förebygga sjukdomar samt minskat antalet oönskade graviditeter i större utsträckning jämfört med förr. Detta har dock också fört med sig negativa effekter och miljöproblem efter att läkemedlen kommer ut i naturen. Ett antal läkemedel är så kallade endokrina störningssubsSynthetic hormones are a group of pharmaceuticals used for various human and animal treatments. However, consumption and disposal of these substances have also given rise to negative effects and environmental problems for organisms in the wild which is why these substances have been classified as estrogenic endocrine-disrupting chemicals (EDCs). Studies on the estrogen receptors (ers) and their ge

Popular Abstract in Swedish För att skydda sig mot omgivande virus, bakterier och parasiter har kroppen utvecklat ett speciellt försvar. Detta försvar utgörs av ett komplext nätverk av celler och lösliga komponenter som interagerar med varandra. En del av kroppens försvar utgörs av fysiska barriärer så som huden och av celler som är specialiserade på att ta upp och döda angripande mikroorganismer.The interaction between murine bone marrow-derived dendritic cells (DC) and the Gram negative bacteria Salmonella typhimurium and Escherichia coli have been characterised. These studies showed that DC phagocytosed and processed S. typhimurium and E. coli expressing defined epitopes for peptide presentation on major histocompatibility complex class I (MHC-I) and class II (MHC-II) molecules. Process

Summary, key points: Transport considerations ought to be factored into the initial phase of the wheelchair & seating assessment process. Manufacturers of wheelchairs and seating systems should make information relating to the safe transportation of their products readily available - and easy to understand. With the desire to provide the safest possible transport environment for wheelchair-se

Background: It is unclear whether thyroid hormone levels are associated with the risk of mortality, cardiovascular disease (CVD) events, or cancer in men with normal TSH. Objectives: We analyzed if serum free T4 (FT4) or TSH is associated with the risk of mortality, incident CVD events, or cancer in Swedish men. Methods: Elderly men (n = 1801; mean age 75 years) in the Gothenburg and Malmö subcoho

Background and aims: Animal studies have suggested that high salt intake might increase the risk of metabolic dysfunction-associated steatotic liver disease (MASLD), but results from populations are mixed, in part due to inadequate salt intake measurement. Salty taste preference is the primary factor leading to salt choice and can reflect habitual salt intake. However, no study has investigated t

The digital healthcare market has been growing rapidly due to the swift development of wearable devices. One notable advancement is the application of digital healthcare technology to vehicles, which is expected to provide a comfortable driving environment and prevent accidents. This study proposed user experience (UX) scenarios to apply and expand digital healthcare technology in vehicles, detail

Jorunn Joiner and Mari Komnæs also employ digital tools, albeit other ones, to shed light on the interaction between narratives of exceptionalism, travel, and place. In ‘Mapping Nordic Exceptionalism with GIS: The Odin Migration Theory and the Search for a Northern Heritage’, they use digital mapping tools to visualise the journeys of two travellers from different centuries in their search for a N

Globular clusters host complex stellar populations whose chemical signatures suggest early (-) retention and reprocessing of stellar ejecta, yet direct evidence for intracluster gas is lacking. Here we present a unified theoretical framework for the evolution of gas in young globular clusters, and its implications for the production of multiple stellar populations. We show that low-velocity AGB wi

The objective for this study was to investigate whether the postural control adaptation during galvanic stimulation of the vestibular nerve were similar to that found during vibration stimulation to the calf muscles. A method for adaptation analysis was used to analyze the evoked changes of posture, stimulus responses and the motion dynamics. The adaptive adjustments of postural control were simil

BACKGROUND: No studies have examined long-term risks for aortic aneurysm (AA) and aortic dissection (AD) or mortality after AA or AD hospitalization among patients with type 2 diabetes mellitus (T2DM).METHODS AND RESULTS: In this observational cohort study, we linked data for patients with T2DM in the Swedish National Diabetes Register, and 5 individually matched population-based control subjects

The ISO22400 standard defines key performance indicators for manufacturing operation management. Its visionary goal is to be applicable to all industry types, regardless the production methodology and the process configuration. Pursuing this objective, a challenging trade-off between generality and specificity in the definitions must be found. In the cited standard, the former approach has been pr

During a metal cutting process, chemical wear can become the dominant mechanism of tool degradation under the high temperatures and contact pressures that arise between the tool and the metal workpiece. This study focuses on the chemical and diffusional interactions between superalloy Inconel 718 and cubic boron nitride (cBN) tool material with and without TiC binder. It covers thermodynamic model

In this study, vegetation optical depth from ESA's Soil Moisture and Ocean Salinity (SMOS) satellite mission is combined with other existing remote sensing, meteorological and literature data in order to obtain values of gravimetric vegetation water content (Mg). The methodology combines an effective medium model valid at passive microwave frequencies with a vegetation dielectric constant model. T

Aim: To assess Ig20Gly tolerability in pediatric patients with primary immunodeficiencies. Patients & methods: Infusion parameters and tolerability were analyzed in pediatric patients (aged 2-5 years [n = 6], 6-11 years [n = 22] and 12-17 years [n = 22]) receiving Ig20Gly in two Phase II/III trials. Results: Of 2624 Ig20Gly infusions, >99% did not require any rate reduction, interruption or di

In vitro generation of antibodies often requires variable domain sequence evolution to adapt the protein in terms of affinity, specificity, or developability. Such antibodies, including those that are of interest for clinical development, may have their origins in a diversity of immunoglobulin germline genes. Others and we have previously shown that antibodies of different origins tend to evolve a