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Consumer goods manufacturers aiming to reduce the environmental impact associated with their products commonly pursue incremental change strategies, but more radical approaches may be required if we are to address the challenges of sustainable consumption. One strategy to realize step change reductions is to prepare a portfolio of innovations providing different levels of impact reduction in excha

Objectives: Maintaining good cognitive function with aging may be aided by technology such as computers, tablets, and their applications. Little research so far has investigated whether internet use helps to maintain cognitive function over time.Design: Two population-based studies with a longitudinal design from 2001/2003 (T1) to 2007/2010 (T2).Setting: Sweden and the Netherlands.Participants: Ol

AbstractShiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli (EHEC). EHEC strains cause gastrointestinal infection and release Stx that can gain access to the circulation. Patients may develop hemolytic uremic syndrome with extensive kidney damage. In the first paper we investigated if blood cell-derived microvesicles released during EHEC infection contain Stx. Toxi

Coal has long been one of the fossil fuels underpinning the energy systems of many countries around the world. Because of its long-standing history, many actors have an interest in retaining the status quo. In this article, we explore the complexities of a coal phase-out in different countries. Drawing on empirical material from Germany, India, Mexico, Serbia and South Africa, we look at the way c

Synovial fluid (SF) may contain cleavage products of proteolytic activities. Our aim was to characterize the degradome through analysis of proteolytic activity and differential abundance of these components in a peptidomic analysis of SF in knee osteoarthritis (OA) patients versus controls (n = 23). SF samples from end-stage knee osteoarthritis patients undergoing total knee replacement surgery an

Histatin 5 is a histidine-rich, intrinsically disordered, multifunctional saliva protein known to act as a first line of defense against oral candidiasis caused by Candida albicans. An earlier study showed that, upon interaction with a common model bilayer, a protein cushion spontaneously forms underneath the bilayer. Our hypothesis is that this effect is of electrostatic origin and that the obser

Product innovation in highly complex and technological areas, such as medical technology, puts high requirements on innovation capability of an organization. Previous research and publications have highlighted organizational issues and learning matters as important and necessary for the development of innovation capability. Action learning require reflections of the ways things are carried out, ch

Boosting innate immunity represents an important therapeutic alternative to antibiotics. However, the molecular selectivity of this approach is a major concern because innate immune responses often cause collateral tissue damage. We identify the transcription factor interferon regulatory factor 7 (IRF-7), a heterodimer partner of IRF-3, as a target for non-antibiotics-based therapy of bacterial in

The conclusions in this paper are drawn from the results of four empirical studies. It has been important to take an empirical approach in the investigation, concerned with internationalization of higher education, since even though plentiful of studies over the last decades have been concerned with internationalization in/of higher education, it has not been from the perspectives from the teacher

Excessive generosity with information about one's private life or the private lives of others, known as ”oversharing”, appears to be an oft-noted phenomenon in the context of ”new” media. I have previously studied this phenomenon in connection with mobile phone conversations in public places. After having eavesdropped on, or maybe rather overheard, such conversations more systematically, I offered

The Swedish pulp and paper industry (PPI) accounts for almost 50 percent of industrial final energy use. It is an energy-intensive industry and process optimization is seen as prerequisite to compete on the global market. This alone should motivate company boards and on-site organisations to put energy management high on the agenda. Definitely, from time to time, energy issues (e.g. fuel shifts, s

This study offers a method for empirically testing theories operationalized in the form of multivariate statistical models. An innovation of the method is that it distinguishes testing into three separate forms, “effect testing,” “prediction testing,” and “theory testing,”where statistical significance plays a separate role in each one. In another innovation, the researcher specifies not only his