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Rapid detection of antibiotic resistance in positive blood cultures by MALDI-TOF MS and an automated and optimized MBT-ASTRA protocol for Escherichia coli and Klebsiella pneumoniae

Introduction: For fast and effective antibiotic therapy of serious infections like sepsis, it is crucial with rapid information about antibiotic susceptibility, especially in a time when the number of infections caused by multi resistant bacteria has escalated in the world. Methods: Here, we have used a semi-quantitative MALDI-TOF-MS based method for antibiotic resistance detection, MBT-ASTRA™, wh

Understanding virtual speakers

This thesis addresses how verbal comprehension is affected by seeing the speaker and in particular when the speaker is an animated virtual speaker. Two people visually co-present – one talking and the other listening, trying to comprehend what is said – is a central and critical scenario whether one is interested in human cognition, communication or learning. Papers I & II are focused on the e

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The introduction of a mollecular method to identify the Entoviruses based on the amplification sequecing and phylogenetic analysis of protein VPI was described. It was proved that this method reduces significantly the time required for the identification of the isolated Entoviruses and that it is very useful in the characterization of isolates which are difficult to typify by the routine immunoloi

Synchrotron XPS and Electrochemical Study of Aging Effect on Passive Film of Ni Alloys

To investigate aging effect on the passive film of Ni23Cr15Mo and Ni22Cr9Mo3Nb, synchrotron-based X-ray photoelectron spectroscopy (XPS) was used to analyze the structure and composition of the air-formed passive film on the alloys. The corrosion resistance of the two Ni alloys in 1 M NaCl solution was evaluated with electrochemical cyclic polarization measurement. The synchrotron XPS measurement

Life-cycle assessment of yeast-based single-cell protein production with oat processing side-stream

Production of fish meal and plant-based feed proteins continues to increase to meet the growing demand for seafood, leading to impacts on marine and terrestrial ecosystems. Microbial proteins such as single-cell proteins (SCPs) have been introduced as feed alternatives since they can replace current fish feed ingredients, e.g., soybean, which are associated with negative environmental impacts. Mic

Metabolically (un)healthy obesity and risk of obesity-related cancers : a pooled study

BACKGROUND: Studies of obesity with or without metabolic aberrations, commonly termed metabolically unhealthy or healthy obesity, in relation to cancer risk are scarce.METHODS: We investigated body mass index (BMI, normal weight/overweight/obesity) jointly and in interaction with metabolic health status in relation to obesity-related cancer risk (n = 23,630) among 797,193 European individuals. A m

Consumer Trust and Platformised Retail Personalisation

As retail is becoming increasingly digitised in its operation and consumer relationships, much faith is put into automation, prediction and insights drawn from consumer data to shape consumer experiences and expectations. Under the umbrella of data-collection and artificial intelligence (AI), this chapter studies the role of consumer trust in retail personalisation. We draw empirical insights from

Major histocompatibility complex class I binding glycopeptides for the estimation of 'empty' class I molecules

Different forms of major histocompatibility complex (MHC) class I heavy chains are known to be expressed on the cell surface, including molecules which are functionally 'empty'. Direct peptide binding to cells is obvious during sensitization of target cells in vitro for cytotoxic T lymphocyte killing and 'empty' MHC-I molecules are comparatively abundant on TAP- 1 2 peptide transporter mutant cell

Complex dynamics of water quality mixing in a warm mono-mictic reservoir

Cycling of water quality constituents in lakes is affected by thermal stratification and homo-thermal conditions and other factors such as oligotrophication, eutrophication, and microbial activities. In addition, hydrological variability can cause greater differences in water residence time and cycling of constituents in man-made lakes (reservoirs) than in natural lakes. Thus, investigations are n

Knee extensor strength and body weight in adolescent men and the risk of knee osteoarthritis by middle age

OBJECTIVES: To assess the extent to which knee extensor strength and weight in adolescence are associated with knee osteoarthritis (OA) by middle age.METHODS: We studied a cohort of 40 121 men who at age 18 years in 1969/1970 underwent mandatory conscription in Sweden. We retrieved data on isometric knee extensor strength, weight, height, smoking, alcohol consumption, parental education and adult

Sustainability of mega water diversion projects : Experience and lessons from China

Water availability and water demand are not evenly distributed in time and space. Many mega water diversion projects have been launched to alleviate water shortages in China. This paper analyzes the temporal and spatial features of 59 mega water diversion projects in China using statistical analysis. The relationship between nine major basins is measured using a network analysis method, and the as

Close stellar encounters at the Galactic Centre - I. The effect on the observed stellar populations

We model the effects of collisions and close encounters on the stellar populations observed in the Milky Way nuclearstellar cluster (NSC). Our analysis is based on N -body simulations in which the NSC forms by accretion of massivestellar clusters around a supermassive black hole. We attach stellar populations to our N -body particles and follow theevolution of their stars, and the rate of collisio

In vitro biomimetic engineering of a human hematopoietic niche with functional properties

In adults, human hematopoietic stem and progenitor cells (HSPCs) reside in the bone marrow (BM) microenvironment. Our understanding of human hematopoiesis and the associated niche biology remains limited, due to human material accessibility and limits of existing in vitro culture models. The establishment of an in vitro BM system would offer an experimentally accessible and tunable platform to stu

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This thesis explores the name, naming and naming politics in three poetic texts which exhibit a concern with the normative force of language: Cristina Peri Rossi’s Evohé (1971), Julia Álvarez’ The Other Side/El otro lado (1995) and Ana Arzoumanian’s (2006) Juana I. In Evohé the woman-body and the woman-word collide and penetrate each other; in The Other Side/ El otro lado the English code conflict

Some theoretical and numerical aspects of the N-body problem

The N-body problem has been studied for many centuries and is still of interest in contemporary science. A lot of effort has gone into solving this problem but it's unlikely that a general solution will be found with the mathematical tools we have today. We review some of the progress that has been made over the centuries in solving it. We take a look at the first integrals, existence of solut

The Humane School

My diploma project is a design proposal for a Rudolf Steiner School in Sirende, a village 12 km outside Kitale Town, Kenya. On Initiative taken by the anthroposophical association Föreningen Sofia in Sweden, a Steiner school opened in Sirende in year 2008. Today the school is in a very bad condition with over crowded classrooms and poor sanitary conditions. The need for a new school building is ur

Leveraging brand co-creation in a digital era: An IKEA case study

Purpose: The purpose is to examine how IKEA works with customer brand co-creation and how it can be further leveraged in the digital era. Methodology: This paper adopts a qualitative case study method, where the primary data consists of an interview with a Social Media Specialist with pre-existing knowledge of brand co-creation at IKEA in Sweden. Furthermore, research about IKEA and the ways they