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In this study, we assessed the proliferative response of peripheral blood mononuclear leukocytes (PBML) from 33 children/young adolescents with chronic dyspepsia, to H. pylori LPS in the presence and absence of IL-2 as a T cell growth factor. A rapid urease test (RUT) and a presence of Helicobacter-like organisms (HLO) in the biopsy specimens allowed us to distinguish RUT/HLO-positive (17/33) and

Autoantibodies to insulin (IAA) are one of the first markers of the autoimmune process leading to type 1 diabetes (T1D). While other autoantibodies in T1D have been studied extensively, relatively little is known about IAA and their binding specificities, especially after insulin treatment is initiated. We hypothesize that insulin antibodies (IA) that develop upon initiation of insulin treatment d

The kinetics of the direct synthesis of acrylonitrile from propane on V-Sb-Al-(W) mixed oxides indicate that acrylonitrile (ACN) forms by two parallel pathways, one directly from propane and the second, which is the prevalent path, through the intermediate formation of propylene (C3=). The limiting factor in the formation of ACN is the relative slowness of the step of allylic oxidation to ACN of t

A new sample-and-hold circuit based on the charge sampling technique is introduced, which integrates input current instead of tracking input voltage to realize high speed and low voltage sampling. Both the theoretical analysis and the experimental results prove that it can realize both sample-and-hold and amplification functions. A 500 MS/s charge sampling circuit is implemented in 0.25 μm CMOS pr

Sorption isotherms (moisture content as a function of relative humidity (RH) at equilibrium) are an important tool in designing buildings to limit moisture related problems. Normally only a single sorption curve is used so that each moisture content uniquely corresponds to one RH. Sometimes two curves are used, one curve for absorption and one for desorption, as it is well known that sorption has

Abstract The aim of this three-year research project is to investigate displacements, i.e. changes in the right to housing and food according to the Swedish Social Service Act between 1982-2018, and its implications for the broader issue of social rights in the welfare state. This is done through the notion of advanced legal practices, which refer to incidents where the dominant current law is con

Sepsis is a life-threatening complication of infection that is characterised by a dysregulated inflammatory state and disturbed hemostasis. Platelets are the main regulators of hemostasis, and they also respond to inflammation. The human pathogen Streptococcus pyogenes can cause local infection that may progress to sepsis. There are more than 200 different serotypes of S. pyogenes defined accordin

Epidemiological studies have found that there is a correlation between red and processed meat consumption and an increased risk of colorectal cancer. There are numerous existing hypotheses on what underlying mechanisms are causative to this correlation, but the results remain unclear. A common hypothesis is that lipid oxidation, which occurs in endogenous lipids and phospholipids in consumed food,

Today, many control applications in cyber-physical systems are implemented on shared platforms. Such resource sharing may lead to complex timing behaviors and, in turn, instability of control applications. This paper highlights a number of anomalies demonstrating complex timing behaviors caused as a result of resource sharing. Such anomalous scenarios, then, lead to a dramatic increase in design c

Binary star systems are assumed to be co-natal and coeval, and thus to have identical chemical composition. In this work, we aim to test the hypothesis that there is a connection between observed element abundance patterns and the formation of planets using binary stars. Moreover, we also want to test how atomic diffusion might influence the observed abundance patterns. We conduct a strictly line-

Active vitamin D, 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)], plays a pivotal role in calcium homeostasis and bone metabolism. Circulating levels of 1,25(OH)(2)D(3) are thought to be dependent mainly on the activity of the renal cytochrome P450 enzyme 25-hydroxyvitamin D(3)-1alpha-hydroxylase (1alpha-hydroxylase), which is potently induced by PTH. However, 1alpha-hydroxylase activity or expressi

Environmental factors, including viral infections, may explain an increasing and fluctuating incidence of childhood type 1 diabetes (T1D). Ljungan virus (LV) isolated from bank voles have been implicated, but it is unclear whether LV contributes to islet autoimmunity, progression to clinical onset, or both, of T1D. The aim was to test whether LV antibodies (LVAb) were related to HLA-DQ and islet a

Förintelsen är ett skrämmande exempel på vad som kan ske när man inte erkänner människors lika värde. Romerna, jämte judarna, var grupper som utsattes för nazisternas systematiska förföljelse på rasmässiga grunder. Trots en traumatisk historia fortsätter Förintelsen av romer att hamna i utkanten av minnespolitiken. Syftet med denna uppsats är att undersöka och analysera närvaron, bristen eller fråThe Holocaust is a frightening example of what can happen when one does not recognize the equal value of human beings. The Romani people, along the Jews, were groups that were exposed to systematic persecution on racial grounds by the Nazi regime. Despite a traumatic history, the Holocaust of Roma continues to end up on the outskirts. The objective of this paper, “To be realised to the extent one

Rysk-amerikanska Emma Goldman och kinesiska He-Yin Zhen kom från två olika delar av världen och var aktiva inom olika kunskapstraditioner och kulturer. Ändå var de båda anarkister som kämpade för kvinnlig frigörelse, och båda var de kritiska till de samtida rörelserna som stred för kvinnors politiska rättigheter. Det finns få studier som jämför tidig amerikansk feminism med tidig kinesisk feminismRussian-American Emma Goldman and Chinese He-Yin Zhen came from different parts of the world, and thus weren’t active within the same knowledge systems and cultures. However, they were both anarchists fighting for the liberation of women, and both were strongly criticising the contemporary women’s suffrage movements. Few comparisons have been made between early Chinese feminism and early American

The cultural significance of dairy milk in Sweden is deeply ingrained, with dairy products being a staple at the breakfast table. However, the past decade has witnessed a formidable challenge to the traditional Swedish dairy industry, with the rise of plant-based milk alternatives. The emergence of new preferences has spurred the ascent of brands like Oatly. The Swedish oat drink producer Oatly, w

Utveckling av en metod för att kartera högsta kustlinjen i Sverige med hjälp av brytlinjer extraherade från högupplösta höjdmodeller Högsta kustlinjens (HK) geografiska läge i landskapet markerar gränsen mellan subakvatiskt och supraakvatiskt avsatta sediment. Idag varierar HKs höjd över havet från några få m.ö.h. i Skåne till omkring 289 m.ö.h. i Ångermanland på grund av den glacialisostatiska lDevelopment of a method for mapping the highest coastline in Sweden using breaklines extracted from high resolution digital elevation models The geospatial position of the highest coastline (HCL) defines the boundary between subaquatic and supra-aquatic deposited sediments. Today the HCL is located at different elevations throughout Sweden, a few m.a.s.l. in southern Scania to around 289 m.a.s.l.

A wireless body area network (WBAN) is a network of compact low power devices that are either wearable or implantable. A compact antenna with suitable radiation pattern and polarization is useful for WBAN applications. Ultra-Wideband (UWB) technology can be used in WBAN applications that require high data rates. This paper present a small wearable (15x17x17 mm) UWB antenna designed and optimized i

S100A4 and S100A9 proteins have been described as playing roles in the control of tumor growth and metastasis. We show here that a chemical probe, oxyclozanide (OX), selected for inhibiting the interaction between S100A9 and the receptor for advanced glycation end-products (RAGE) interacts with both S100A9 and S100A4. Furthermore, we show that S100A9 and S100A4 interact with RAGE and TLR4; interac

Gestational enterovirus (EV) infections have been associated with an increased risk for type 1 diabetes in the offspring. We therefore analyzed non-diabetic mothers for EV exposure in early pregnancy in relation to type 1 diabetes HLA-DQ risk genotypes and seroconversion to islet autoantibodies during pregnancy. Non-diabetic mothers who had islet autoantibodies (n=365) against glutamic acid decarb

Objective: Primary adrenal insufficiency [Addison's disease (AD)] is rare, and systematic studies are few, mostly conducted on small patient samples. We aimed to determine the clinical, immunological, and genetic features of a national registry-based cohort. Design: Patients with AD identified through a nationwide search of diagnosis registries were invited to participate in a survey of clinical f