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Background: Occurrence of severe asthma exacerbations are the cornerstone of the evaluation of asthma management, but severe asthma exacerbations are rare events. Therefore, trials that assess drug efficacy on exacerbations are done late in clinical development programmes. We aimed to establish an endpoint capturing clinically relevant deteriorations (diary events) that, when combined with severe

In this chapter, we explore whether eyeblinks can be used as a measurementof spectators’ narrative transportation into a cinematic narrative. In ourexperiment, we show that spectators’ eyeblinks increase when watchingfilm clips together with what might be called congruent music. Increasedeyeblinks indicate an emotional arousal that motivates attention, whichin turn is a prerequisite for narrative

Countries all over Europe have faced growing migration figures since World War II. Not least immigration from countries far away from European traditions and culture will make an impact in general and also when it comes to food, meals and eating. The estimation is that more than one out of five Swedes in now living generations has roots in other countries and cultures. Segregation from aspects of

Recognition and removal of apoptotic and necrotic cells must be efficient and highly controlled to avoid excessive inflammation and autoimmune responses to self. The complement system, a crucial part of innate immunity, plays an important role in this process. Thus, apoptotic and necrotic cells are recognized by complement initiators such as C1q, mannose binding lectin, ficolins, and properdin. Th

Lean premixed dry low emission (DLE) combustion system in a gas turbine engine is a globally accepted concept to reduce pollutant emissions and to improve combustion efficiency. This study is focused on an industrial downscaled prototype burner (4th Generation Dry Low Emission Burner for SGT-750 designed and manufactured by Siemens Industrial Turbo machinery AB), which has been tested extensively

Many animals are known to preferentially mate with partners that are dissimilar at the major histocompatibility complex (MHC) in order to maximize the antigen binding repertoire (or disease resistance) in their offspring. Although several mammals, fish or lizards use odour cues to assessMHCsimilarity with potential partners, the ability of birds to assessMHC similarity using olfactory cues has not

We know that planetary systems are just as common around white dwarfs as around main-sequence stars. However, self-consistently linking a planetary system across these two phases of stellar evolution through the violent giant branch poses computational challenges, and previous studies restricted architectures to equal-mass planets. Here, we remove this constraint and perform over 450 numerical int

Background: Symptoms have been identified as a core outcome domain for atopic eczema (AE) trials. Various instruments exist to measure symptoms in AE, but they vary in quality and there is a lack of standardization between clinical trials. Our objective was to systematically evaluate the quality of the evidence on the measurement properties of AE symptom instruments, thereby informing consensus di

A simple assay was developed to estimate functional mannose-binding lectin (MBL) levels in serum based on the principle of yeast-induced bystander lysis of chicken erythrocytes (ChE). The assay is sensitive to inhibition by ethylene glycol bis-(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA) (which allows alternative pathway activation), ethylene diamine tetraacetic acid (EDTA), mannose,

The extracellular matrix consists of structural macromolecules and other proteins with regulatory functions. An important family of the latter class of molecules found in most tissues is the small leucine-rich repeat proteins (SLRPs). We have previously shown that the SLRP fibromodulin binds directly to C1q and activates the classical pathway of complement. In the present study we further examine

An indirect 125I-labeled protein A assay for detection of cell surface-bound rat immunoglobulins is presented. The assay is quantitative and rapid and detects as little as 1 ng of cell surface-bound Ig. It discriminates between antibodies belonging to different IgG subclasses, IgM and IgA. We describe the production and specificity control of the reagents used and show that the test can be used fo

Syftet med denna studie är att undersöka vad som får elever att börja spela brassinstrument och vilka faktorer som motiverar dem till att fortsätta på Musik- och Kulturskolan. Bakgrunden till studien är att antalet elever på brassinstrumenten i Musik- och Kulturskolorna har minskat i Sverige under lång tid. Data består av gruppintervjuer med 11 elever i tre åldersbaserade grupper. Resultatet viThe purpose of this study is to investigate what motivates students to begin playing a brass instrument and the factors that motivate them to continue in the Community School of Music and Arts. The background for this study is that the number of students on brass instruments in the Community Schools of Music and Arts in Sweden has been decreasing for many years. Data collection was performed thro

The present study aimed to investigate the relationship between growth rate, final mass, and larval development, as well as how this relationship influences reproductive trade-offs, in the context of a gregarious life-style and the need to keep an optimal group size. We use as a model two sympatric populations of the pine processionary moth Thaumetopoea pityocampa, which occur in different seasons

The Thomson multitaper estimator has become successful for spectrum analysis in many application areas. From the aspect of efficient implementation, the so called Welch or WOSA- Weighted Overlap Segment Averaging, has advantages. In the Welch estimator, the same, time-shifted, window is applied to the data-sequence. In this submission, the aim is to find a Welch estimator structure which has a sim

1 Water’s Journey from Rain to Stream by Harald Grip and Allan Rodhe Preliminary translation into English by Harald Grip and Kevin Bishop (edited January 2015) The Swedish edition: Grip, H. and Rodhe, A., 2000, Vattnets väg från regn till bäck, Hallgren & Fallgren, Uppsala (earlier edition Forskningsrådens förlagstjänst 1985) 2 Contents 1. The origin of streamwater – a controversy ................

https://www.nateko.lu.se/sites/nateko.lu.se/files/waters_journey_jan2015a.pdf - 2026-05-28

This thesis explores current trends in social and political organising in Northern Syria, in areas controlled by the PYD. The research is built on discussions between eight participants from the Syrian Kurdish-speaking community living in the areas. While most discourses on Syria and the Kurdish-speaking community have a macro-political focus and produce racialising descriptions of “Kurdishness” i

This report is the result of a fire safety evaluation of the Royal Opera in Stockholm. This report was written as a project by students at the fire protection engineering program at Lund University. The objective of the evaluation is to ensure successful egress of visitors of the Royal Opera in case of fire. No concern has been taken of environmental or economical damage nor the safety of the staf

Background: In a previous study, we explored real-world programmed death-ligand 1 (PD-L1) testing and treatment patterns for patients with advanced non-small cell lung cancer (NSCLC) in the era of immune-oncology. The present study aimed to investigate overall survival (OS) with PD-(L)1 inhibitors with longer-term follow-up in the Swedish setting. Materials and methods: Data were extracted from th