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A computational algorithm for the full information H∞ control problem for multi-delayed LTI systems is derived. The algorithm is based on a general operator approach in the spectral domain developed for finite-dimensional LTI plants. The simplicity of spectral operations and explicit formulas for computation make it possible to generalize it to infinite-dimensional plants. In the paper, a complete

Despite rigorous efforts to improve the construction working environment in the European Union, the fatal accident rate is approximately 13 workers per 100,000 as against 5 per 100,000 for the all sectors average. Although the accident rates have declined steadily and steeply since 1994, it still remains unacceptably high. Thousands of construction workers still suffer severe injury and even death

Purpose of this paper: Logisticians propose changes to improve supply chains, and legal practitioners are doing likewise, but from a tax perspective. Proposals from one domain increasingly have an impact on the other due to e.g. globalisation – but cross-disciplinary knowledge often seems small. Our purpose is to facilitate interaction between the domains by increasing joint understanding o

PURPOSE: To compare the clinical outcome after carpal tunnel release in diabetic and nondiabetic patients. METHODS: We evaluated a prospective, consecutive series of 35 diabetic patients (median age, 54 years; 15 with type 1 and 20 with type 2 diabetes) with carpal tunnel syndrome, who were age- and gender-matched with 31 nondiabetic patients (median age, 51 years) having idiopathic carpal tunnel

We have addressed the importance of B cell tolerance to collagen type II, a matrix protein, which is a target in rheumatoid arthritis (RA) and its mouse models. We generated a germline-encoded anti-collagen type II (CII) IgH replacement anti-C1 B cell mouse strain (ACB) to investigate how B cell tolerance to CII, a matrix protein, is subverted and to further understand pathogenesis of RA. Phenotyp

That a load balancing strategy using stale information care lessly will incur system performance degradation is easy to verify. However it is not so obvious that routing a customer to the expected shortest queue has the same problem when information for decision is stale. We consider a queueing system with a load balancer and a pool of identical FCFS queues in parallel. The arrival process is assu

BACKGROUND: Differential gene expression in adipose tissue during diet-induced weight loss followed by a weight stability period is poorly characterized. Markers of these processes may provide a deeper understanding of underlying mechanisms. OBJECTIVE: We aimed to identify differentially expressed genes in human adipose tissue during weight loss and weight maintenance after weight loss. DESIGN:

This review examines evidence that rheumatoid arthritis (RA) depends on autoimmunity to articular collagen, and mechanisms whereby autoantibodies to type II collagen contribute to disease development. Three major autoantigenic reactants have been identified in RA; the corresponding autoantibodies are rheumatoid factor (RF), antibodies to citrullinated peptide antigens (ACPA), citrullinated peptide

Erythroblast transformation-specific domain (ETS) transcription factors regulate some of the critical molecular mechanisms controlling the differentiation of multipotent haematopoietic progenitor cells into effector B-lymphocytes. The SPI-group ETS-protein transcription factors PU.1 and SPI-B play essential and, although coexpressed and binding to similar DNA sequences, unique roles in B-cell diff

This paper describes the implementation of a structure assessmentmethod in an industrial control system. The method uses available signals to evaluate if a given signal can be used for additional feed forward control action to improve the performance of a control loop.

The neuropeptide WE-14 is derived from the posttranslational processing of chromogranin A (CgA). While CgA is expressed in a preponderance of neuroendocrine cells, WE-14 is generated in a distinct subpopulation of CgA-immunopositive cells, most notably in the adrenal, pituitary, and parathyroid glands. Physiological and pharmacological studies have demonstrated that CgA is cleaved to generate WE-1

Sterile liver inflammation and fibrosis are associated with many liver disorders of different etiologies. Both type 1 and type 2 inflammatory responses have been reported to contribute to liver pathology. However, the mechanisms controlling the balance between these responses are largely unknown. Natural killer T (NKT) cells can be activated to rapidly secrete cytokines and chemokines associated w

We investigate the dissolution process of star clusters embedded in an external tidal field and harboring a subsystem of stellar-mass black hole. For this purpose we analyzed the MOCCA models of real star clusters contained in the Mocca Survey Database I. We showed that the presence of a stellar-mass black hole subsystem in tidally filling star cluster can lead to abrupt cluster dissolution connec

The question of who China’s leftover men will marry is becoming a pressing issue for Beijing. The government’s response will shape the country’s future for decades to come.

BACKGROUND: Human diets account for 30% of greenhouse gas emissions (GHGE). Reporting dietary GHGE with or without energy standardization yields different outcomes, often resulting in conflicting conclusions regarding associations with micronutrient intake.OBJECTIVES: To compare methods of reporting dietary GHGE, with and without consideration of energy intake, and their respective associations wi

How mergers affect galaxy formation depends on both feedback processes, and on the geometry and strength of the mergers themselves. We introduce the PARADIGM project, where we study the response of a simulated Milky-Way-mass galaxy (M200c ∼ 1012 M at z = 0) forming in a cosmological setting to differing merger histories, using genetically modified initial conditions, each simulated with the VINTER