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The new di- and tetranuclear Fe(III) μ-oxido complexes [Fe 4 (μ-O) 4 (PTEBIA)

Aims of the study: Neurological impairment after resuscitated cardiac arrest (CA) remains a significant unmet medical need. Brain ischemia associated with CA and subsequent reperfusion is evident as two fundamentally different types of damage on neuropathological examination: frank necrosis (involving all cell types) and selective eosinophilic neuronal death (SEND). These types of damage are not o

Background: Long-term follow-up (LTFU) care for childhood, adolescent, and young adult (CAYA) cancer survivors is essential to preserve health and quality of life (QoL). Evidence-based guidelines are needed to inform optimal surveillance strategies, but many topics are yet to be addressed by the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG). Therefore, the Pan

This thesis examines the reaction of political institutions to the structural transformation of the British economy from 1700 to 1850. The majority of the literature on the relationship between institutions and economic growth conceptualises the political institutions as a precondition to modern economic growth in the British context. Getting its inspiration from Lennart Schön’s theoretical fra

Procedural sedation and analgesia outside the operating theater have become standard care in managing pain and anxiety in children undergoing diagnostic and therapeutic procedures. The objectives of this study are to describe the current pediatric procedural sedation and analgesia practice patterns in European emergency departments, to perform a needs assessment-like analysis, and to identify barr

This article examines the continuities and discontinuities in the historical trajectory of the commercialisation of places. It outlines a performative approach to understanding how the process of turning cities into com- mercial products changes in time and space. Stockholm, the capital of Sweden, is used as an illustrative example of the spatio-temporal trajec- tory of commercialisation during th

Introduction: The aim of this study was to evaluate if surface guided radiotherapy (SGRT) can decrease patient positioning time for localized prostate cancer patients compared to the conventional 3-point localization setup method. The patient setup accuracy was also compared between the two setup methods. Materials and methods: A total of 40 localized prostate cancer patients were enrolled in this

Do radical right parties present blurry economic stances, or have they clarified their positions while moving towards the economic left? This article questions the strategic behaviour of radical right parties in Western Europe. It shows that although radical right parties have increased their discussion of economic issues, and expert placements of this party family on the economic dimension have b

Using survey vignettes and scaling techniques, we estimate common socio-cultural and European integration dimensions for political parties across the member states of the European Union. Previous research shows that party placements on the economic left-right dimension are cross-nationally comparable across the EU; however, the socio-cultural dimension is more complex, with different issues formin

After peptide release by a class-1 release factor, the ribosomal subunits must be recycled back to initiation. We have demonstrated that the distance between a strong Shine-Dalgarno (SD) sequence and a codon in the P site is crucial for the binding stability of the deacylated tRNA in the P site of the posttermination ribosome and the in-frame maintenance of its mRNA. We show that the elongation fa

Experimental governance is increasingly being implemented in cities around the world through laboratories, testbeds, plat- forms, and innovation districts to address a wide range of complex sustainability challenges. Experiments often involve public-private partnerships and triple helix collaborations with the municipality as a key stakeholder. This stretches the responsibilities of local authorit

Some of the most fundamental chemical building blocks of life on Earth are the metal elements. X-ray absorption spectroscopy (XAS) is an element-specific technique that can analyse the local atomic and electronic structure of, for example, the active sites in catalysts and energy materials and allow the metal sites in biological samples to be identified and understood. A microfluidic device capabl

Over the past decade, as ruling Justice and Development Party (AKP) initiated Turkey’s authoritarian populist turn, it sought to derive legitimacy through extra-institutional avenues, notably the emotional appeal to the repressed “people”, advancing the party’s socio-political vision, countering the arguments of its political opponents and reaching out to, and inspiring its constituency. Turkey’s

Adequate setting of the boundary conditions for the heat equation when modeling the temperature distribution in the cutting tool is one of the key points. The boundary conditions on the tool surfaces can be divided into two groups: conditions that describe heat losses (heat exchange with the environment) and conditions that characterize the heat source that heats up the tool (heat flux from the cu

Purpose: Preclinical studies using a new treatment modality called FLASH Radiotherapy (FLASH-RT) need a two-phase procedure to ensure minimal uncertainties in the delivered dose. The first phase requires a new investigation of the reference dosimetry lying outside the conventional metrology framework from national metrology institutes but necessary to obtain traceability, repeatability, and stabil

Binge eating disorder (BED) is associated with several psychological and medical problems, such as obesity. Approximately 30% of individuals seeking weight loss treatments present binge eating symptomatology. Moreover, current treatments for BED lack efficacy at follow-up assessments. Developing mindfulness and self-compassion seem to be beneficial in treating BED, although there is still room for

Intrinsic molecular subtypes may explain marked variation between bladder cancer patients in prognosis and response to therapy. Complex testing algorithms and little attention to more prevalent, early-stage (non-muscle invasive) bladder cancers (NMIBCs) have hindered implementation of subtyping in clinical practice. Here, using a three-antibody immunohistochemistry (IHC) algorithm, we identify the

Critical infrastructures (CIs) and the services they provide are imperative for the functioning of societies. CI safety and security have historically been addressed and regulated on a sectoral basis, despite their interdependent nature. These silo-structures potentially hinder achieving resilience from a system-of-systems governance perspective. Cross-sectoral initiatives addressing interdependen