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In an earlier study, infection of human pancreatic islets with epidemic strains of echovirus (E4, E16, E30), with proven but differently ability to induce islet autoimmunity, resulted either in a severe damage (i.e. E16 and E30) or proceeded without visible changes in infected islets (i.e. E4). In this study, the ability of these strains to replicate in beta cells and the consequence of such an in

Thermostimulated and photostimulated luminescence of ZnWO4, ZnWO4:Fe and ZnWO4:MO Crystals irradiated at low temperatures by X-rays or UV photons was studied in the temperature range 4.2-300 K in order to clarify the creation and recombination processes of the elementary colour centres. The connection of the luminescence phenomena with the self-trapped holes has been revealed. (C) 2003 Published b

The majority of the spinal injuries (60 %) affect young healthy males between 15 and 35 years of age with cervical spine injuries to be most common. The main cause for spinal injuries is blunt trauma most commonly due to motor vehicle accidents (48 %), followed by falls (21 %), and sport injuries (14.6 %). Assault and penetrating trauma account for approximately 10-20 % of the cases. Injuries to t

The kidneys are the major organs affected in diarrhea-associated hemolytic uremic syndrome (D(+)HUS). The pathophysiology of renal disease in D(+)HUS is largely the result of the interaction between bacterial virulence factors such as Shiga toxin and lipopolysaccharide and host cells in the kidney and in the blood circulation. This chapter describes in detail the current knowledge of how these bac

The Netherlands is a small country with a relatively large population which experienced a rapid rate of land use changes from 2000 to 2008 years due to the industrialization and population increase. Land use change is especially related to the urban expansion and open agriculture reduction due to the enhanced economic growth. This research reports an investigation into the application of remote se

Image processing is one of the popular applications of Cellular Neural Networks. Macro enriched field-programmable gate-arrays can be used to realize such systems on silicon. The paper discusses a pipelined implementation that supports the handling of gray-level images at 180 to 240 Mpixels per second by exploiting the Virtex-II macros to spatially unroll the local feedback

This paper presents an unbalanced overview of existing Enterprise Resource Planning (ERP) research by reassessing the body of knowledge and emphasising future research directions that need to be pursued in an attempt to fill knowledge gaps and bridge the existing gap between practitioners and academia. To fulfil this objective, nine leading international IS publications covering the period of 2006

Abstract in UndeterminedThe paper describes a magnetizing machine for producing permanent magnets of desired magnetization pattern by use of feedback control. This will in theory mean that an ideal magnetization pattern can be realized, what could be described as a perfect magnet. The machine is to be used for applications requiring high accuracy magnets in terms of the shape of the magnetized are

Popular Abstract in Swedish Varje år insjuknar omkring 300 barn i cancer. Förbättrade behandlingsmetoder under de senaste decennierna har lett till att mer än tre av fyra barn idag faktiskt botas från sin sjukdom. Tyvärr drabbas en stor andel av de som överlever sin cancer av så kallade sena komplikationer till följd av den tuffa behandling de har utsatts för. Bland annat har man sett en livslång The etiology of childhood cancer is largely unknown. Approximately 1-10% of all childhood tumors are associated with known cancer predisposition syndromes. However, the contribution may be underestimated due to the failure to detect patients with genetic susceptibility for cancer when relying on known family pattern and anomalies. Growing evidence indicates that patients with genetic susceptibilit

Protection against mucosally transmitted infections probably requires immunity at the site of pathogen entry(1), yet there are no mucosal adjuvant formulations licensed for human use. Polyethyleneimine (PEI) represents a family of organic polycations used as nucleic acid transfection reagents in vitro and DNA vaccine delivery vehicles in vivo(2,3). Here we show that diverse PEI forms have potent m

Human monocytes are a heterogeneous cell population classified into three different subsets: Classical CD14++CD16-, intermediate CD14++CD16+, and non-classical CD14+CD16++ monocytes. These subsets are distinguished by their differential expression of CD14 and CD16, and unique gene expression profile. So far, the variation in inter-cellular gene expression within the monocyte subsets is largely unk

Determining the electronic and geometric structures of photoexcited transient species with high accuracy is crucial for understanding their fundamental photochemistry and controlling their photoreactivity. We have applied X-ray transient absorption spectroscopy to measure the XANES and EXAFS spectra of a dilute (submillimolar) solution of the osmium(II) polypyridyl complex [Os(bpy)(2)dcbpy](PF6)(2

Our study had three objectives: to extend the plasmid-based transformation protocol to a clinical isolate of C. trachomatis belonging to the trachoma biovar, to provide "proof of principle'' that it is possible to "knock out'' selected plasmid genes (retaining a replication competent plasmid) and to investigate the plasticity of the plasmid. A recently developed, plasmid-based transformation proto

There are all sorts of consumer electronics in a home environment. Using ”apps” to interact with each device is neither feasible nor practical in an ubicomp future. Prototyping and evaluating interaction concepts for this future is a challenge. This paper proposes four concepts for device discovery and device interaction implemented in a virtual environment. The interaction concepts were compared

Feedback in server systems has during last years gained much interest in order to fulfill still increasing demands on performance and optimization regarding, for example, quality of service (QoS) requirements. In this paper we investigate a feedback–based prediction scheme for controlling a single server queue. This control structure has the benefit over other previously suggested control structur