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BACKGROUND AND OBJECTIVES: Polymorphic molecules expressed on the surface of certain blood cells are traditionally categorized as blood groups and human platelet or neutrophil antigens. CD36 is widely considered a platelet antigen (Nak a ) and anti-CD36 can cause foetal/neonatal alloimmune thrombocytopenia (FNAIT) in CD36-negative pregnant women. CD36 is used as a marker of differentiation in earl

Dendritic cells (DCs) with capacity of antigen cross-presentation are of key interest for immunotherapy against cancer as they can induce antigen-specific cytotoxic T lymphocyte (CTL) responses. This study describes frequencies of DC subtypes in human tonsils and lymph nodes, and phenotypic aspects that may be targeted by adjuvant measures. From human tonsils and neck lymph nodes, DCs were identif

Gut-associated lymphoid tissues (GALT) are the key antigen sampling and adaptive immune inductive sites within the intestinal wall. Human GALT includes the multi-follicular Peyer's patches of the ileum, the vermiform appendix, and the numerous isolated lymphoid follicles (ILF) which are distributed along the length of the intestine. Our current understanding of GALT diversity and function derives

Western Sierra Morena constitutes a singular link between the Roman provinces of Baetica and Lusitania, in terms of its physiography and historical development. This region, characterised by its rugged topography, forests, and abundant mineral resources, was decisively transformed after the Roman conquest. Such transformations are visible in the characteristics of the archaeological record and in

The aim of the present paper is to explore the interrelated and complex relationships between religionsvetenskap (Religious Studies), religionskunskap (Religious Education) and religionsdidaktik (Religion and Education). After briefly outlining the concurrent developments of Religious Studies as a university discipline and Religion and Eudcation as a non-confessional school subject, both of which

Although gamification is a popular term, the concept has rarely been applied to political studies. Therefore, this chapter provides an overview of the key features of gamification and offers an adapted definition of gamification suited to the study of electoral politics. To help illustrate this definition, two examples of gamification from recent campaigns are discussed: the uCampaign mobile appli

Background: Optimal oxygen targets in patients resuscitated after cardiac arrest are uncertain. The primary aim of this study was to describe the values of partial pressure of oxygen values (PaO2) and the episodes of hypoxemia and hyperoxemia occurring within the first 72 h of mechanical ventilation in out of hospital cardiac arrest (OHCA) patients. The secondary aim was to evaluate the associatio

CONTEXT: It is important to identify patients at highest risk of fractures. OBJECTIVE: To compare the separate and combined performances of bone-related genetic risk scores (GRSs) for prediction of forearm, hip and vertebral fractures separately, as well as of trabecular and cortical bone microstructure parameters separately. DESIGN, SETTING, AND PARTICIPANTS: Using 1103 single nucleotide polymorp

Background: Tinnitus sufferers commonly report concentration difficulties. Despite several previous studies investigating this, the underlying cause and the role of hearing status remains unclear. Purpose: To investigate whether there are any differences between normal hearing individuals with and without tinnitus in terms of working memory capacity, and whether working memory capacity correlates

A nonlinear autotuning regulator algorithm is obtained via a direct combination of the Åström-Hägglund algorithm for the linear case [1] with the sinusoidal-input describing function (SIDEF) approach to nonlinear compensator synthesis of Taylor and Strobel [2]. The basic approach for linear autotuning proceeds as follows: a. install a relay with hysteresis in series with the unknown plant to be co

Cancer cells are characterized by chromosome abnormalities, of which some, in particular balanced rearrangements, are associated with distinct tumor entities and/or with specific gene rearrangements that represent important steps in the carcinogenic process. However, the vast majority of cytogenetically detectable structural aberrations in cancer cells have not been characterized at the nucleotide

Problemet med förfalskade läkemedel är stort globalt. Patienter med svårbedömdasymtom kan ha biverkningar av sådana. Läkare behöver vara mer medvetna om förekomsten av förfalskade läkemedel, och veta hur de ska handskas med problemet.

Substandard and falsified (SF) medical products are a major danger to public health. They affect every region of the world, and have been identified in all major therapeutic categories. Studies from medicine, pharmacology, law and public health dominate this research area with a focus on the supply side. However, the spread of SF medical products cannot be fully understood without information abou

Sustainability of the enterprise is crucial to support long-term business survival and development. Unpredictable events such as Covid-19 highlights sustainability issues in enterprises. This empirical study aims to investigate sociotechnical sustainability in real world work practices. The focus is on employee involvement and problems in work practices concerning the economic, environmental, soci

OBJECTIVE: Twin studies have demonstrated that posttraumatic stress disorder (PTSD) is moderately heritable, and the pattern of findings across studies suggests higher heritability in females compared with males. Formal testing of sex differences has yet to be done in twin studies of PTSD. The authors sought to estimate the genetic and environmental contributions to PTSD, and to formally test for

Hunting tourism, broadly defined as travelling to other places other than one´s usual home or work environment for recreational hunting, takes many forms. It can be seen as a form of special interest tourism in the border area between recreation and tourism, and between market and non-market. In Sweden, there is an established form of reciprocal domestic hunting tourism, where hunting in other dom

How the avian sex chromosomes first evolved from autosomes remains elusive as 100 million years (My) of divergence and degeneration obscure their evolutionary history. The Sylvioidea group of songbirds is interesting for understanding avian sex chromosome evolution because a chromosome fusion event ∼24 Ma formed "neo-sex chromosomes" consisting of an added (new) and an ancestral (old) part. Here,