Search results

The presented work describes a computational method for carrying out a detailed and thorough examination of the flash temperature rise (i.e. the local’instantaneous’ temperature increase on a contact interface, due to frictional effects) present on the tooth flanks of a polymer gear pair, composed of a combination of POM and PA66 thermoplastics, during a given meshing cycle. The method involves a

Interleukin-15 (IL-15) is a cytokine that has been shown to expand CD8 T cell and natural killer (NK) cell populations, and therefore has potential for potentiating adoptive immune cell therapy for cancer. Previously, IL-15 has been shown to induce proliferation of CD8 memory T cells through activation of telomerase. Here, we investigated whether telomerase is also activated during the IL-15 media

Activated normal density granulocytes (NDGs) can suppress T-cell responses in a similar way as myeloid-derived suppressor cells (MDSCs). In this study, we tested the hypothesis that NDGs from blood and bone marrow of multiple myeloma (MM) patients have the ability to suppress T-cells, as MDSC. MM is an incurable plasma cell malignancy of the bone marrow. Like most malignancies, myeloma cells alter

Chronic breathlessness is a dominating symptom that restricts daily life for many people with cardiorespiratory disease [1]. Different dimensions of the symptom, such as the intensity, sensory qualities and emotional responses, can be assessed using the instruments Dyspnea-12 (D-12) [2] and the Multidimensional Dyspnea Profile (MDP) [3], which share similarities in the underlying constructs of wha

INTRODUCTION: Complement-mediated atypical hemolytic uremic syndrome (aHUS) is an ultra-rare renal disease primarily caused by genetic alterations in complement proteins. The genetic work-up required for confirmation of diagnosis is complicated and not always logistically accessible. The aim of the present study was to apply a diagnostic scheme compliant with the ACMG guidelines to investigate the

The aim is to test the reliability of two alcohol screening instruments: (1) The Parent Alcohol Screening Questionnaire (PASQ5), and (2) the Social Support for an Alcohol-free Pregnancy (SSAFP) questionnaire. This is a cohort study from the south of Sweden using repeated surveys during pregnancy. To examine if responses differed according to different data collection methods, two cohorts consistin

A full-duplex relay enhances the end-to-end spectral efficiency compared to a half-duplex relay, provided that the loop-back interference at relays is managed well. In order to study the feasibility of the full-duplex relay, it is crucial to measure and model the loop-back interference channels. This paper presents a measurement campaign of these channels for outdoor-to-indoor communications. A co

CONTEXT: Psychiatric symptoms are common in Cushing's disease (CD) and seem only partly reversible following treatment. OBJECTIVE: To investigate drug dispenses associated to psychiatric morbidity in CD patients before treatment and during long-term follow-up. DESIGN: Nationwide longitudinal register-based study. SETTING: University Hospitals in Sweden. SUBJECTS: CD patients diagnosed between 1990

LukGH (LukAB) is a potent leukocidin of Staphylococcus aureus that lyses human phagocytic cells and is thought to contribute to immune evasion. Unlike the other bi-component leukocidins of S. aureus, LukGH forms a heterodimer before binding to its receptor, CD11b expressed on professional phagocytic cells, and displays significant sequence variation. We employed a high diversity human IgG1 library

Magnesium metal and its alloys are lightweight and environment-friendly with tunable complex of structural and functional properties. However, significant gaps in understanding and assessing the degradation of these materials still remain, largely due to the limitations of existing experimental methods. Our novel laboratory-scale instrument combining isothermal calorimetry with pressure measuremen

This article explores how the NT accounts of the rending of the veil in the Temple at the time of Jesus have been interpreted: as a sign of wrath, joy and grief.

n this paper a hardware architecture for an OFDM synchronizer is presented. The proposed synchronization unit can be used in any OFDM system that uses a cyclic prefix. The algorithm is based on the correlation introduced by the cyclic prefix, which is exploited in the time domain where both time and frequency offset are estimated simultaneously. The synchronization unit also performs frequency cor

This paper presents in some detail findings and experiences gained from a new course entitled “Innovation Engineering” (IE). This course is offered in the Technology Management Programme (TM) at Lund University, Lund, Sweden. The incentive for developing the new course was the need for a more integrated and practical approach where technical, customer and application problems from reality confront

The elemental composition of the St. Louis aerosol has been investigated at rooftop sites in south and central locations in the city as part of the August, 1973 field season of the Regional Air Pollution Study of the U.S. Environmental Protection Agency. Sampling by 5-stage cascade impactor with backup filter permits analysis by proton-induced x-ray emission (PIXE) of size fractions of aerodynamic