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Galiellalactone is a fungal metabolite found in the basidiomycetes Galiella rufa and the unidentified strain A111-95. It has been shown to possess promising activities as an inhibitor of the IL-6 mediated STAT3 signaling in HepG2 cells. Targeting this pathway is very important when it comes to understanding intracellular signaling and also for developing drugs for treating diseases associated with

The paper focuses on a suite of fable texts from the modern epoch, the “Fables” of August Strindberg, written in the 1880s. In most of these ten prose fables the protagonists are anthropomorphized animals, one of the facts clearly connecting the suite with the Aesopic tradition, which Strindberg was highly familiar with. The basic message of the Aesopic genre – the rejection of man’s animality as

One of the most important aspects of the marriage legislation in medieval canon law is the doctrine of free choice. According to this doctrine, established by pope Alexander III in the second half of the twelfth century, the validity of a marriage depended solely on the freely given consent of the parties. No one could legally force a couple to marry if they did not freely consent to do so. In par

Popular Abstract in Swedish Denna studie fokuserar på reproduktionskostnader och de energetiska taktiker som en reproducerande individ kan utnyttja för att tillfredsställa det ökade behovet av energi och näring under reproduktionen. Reproduktionskostnader har traditionellt definierats som reduktioner av den framtida potentiella produktionen av avkomma, orsakade av en nuvarande reproduktiv investerThis study focuses on various aspects of costs of reproduction and the evolution of energetic breeding tactics. It emphasizes the distinction between demographic costs of reproduction expressed already before current offspring have reached independence (prebreeding costs), and costs expressed only after offspring independence (postbreeding costs). Prebreeding costs have only rarely been appreciate

The initiation of a migraine attack involves a primary central nervous system dysfunction with subsequent activation of the trigeminovascular system. In trigeminal ganglia, the expression of calcitonin gene-related peptide (CGRP), substance P (SP) and nitric oxide synthase (NOS) have been demonstrated by immunocytochemistry. During migraine attacks, the level of released CGRP is increased. Meanwhi

Popular Abstract in Swedish Bindväv är ett samlingsnamn för vävnader som ger form och struktur i olika organ i kroppen. I brosk och ben utgör bindväven hela eller stora delar av organet, medan i andra organ, t.ex. muskel, är bindväven endast en liten del. Bindväv karaktäriseras av ett nätverk av proteiner och polysackarider (extracellulär matrix), som omger och produceras av en relativt liten andeThis thesis describes the structure and interactions of a novel extracellular matrix protein - PRELP (proline arginine-rich end leucine-rich repeat protein). The amino acid sequence of PRELP showed that it belonged to the leucine-rich repeat (LRR) protein family in connective tissues. The main part of PRELP is composed of 10 LRRs flanked by disulfide bridges at the amino- and carboxy-terminal end

The article examines four motifs/textual corpora in the Bible which have been referred to by those in favour of slavery: (1) the Exodus motif, (2) the Curse of Noah, (3) the parables of Jesus, and (4) the epistles of Paul. It is argued in the article that Christianity, with its canonized metaphors of slavery actually delayed the abolition of slavery in the 19th century by relativizing and idealizi

Introductory chapter to anthology, 'Cultures of Doing Good: Anthropologists and NGOs' Ed. by Amanda Lashaw, Steven Sampson, and Christian Vannier, Under review-in press with Univ of Alabama Press., November 2015. Presented at the Roundtable on NGOgraphy, American Anthropological Association Annual Meetings, Denver, 17 November 2015. This chapter describes the dialectic between fieldwork engagement