Search results

Intracellular deposits of neurofibrillary tau tangles and extracellular Aβ plaques are closely associated with Alzheimer’s disease. The mapping of thermodynamic parameters, including solubility limits, indicates when a protein forms amyloid fibrils or remains in solution. This reveals the direction of change of the system and may help in understanding drift and steady states in living systems. Her

The clustering of certain proteins into oligomers and fibrils, known as amyloids, underlies the pathology of diseases such as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes. These processes are counteracted by the cellular protein quality control system, which includes molecular chaperones that interact with disease-associated proteins. One such chaperone is DNAJB6b, which has gaine

Geographers have shown how mobile phones are transforming urban economies in Africa by altering the temporal and spatial nature of commercial transactions. Less well documented is how young people in Africa are using mobile phones to navigate the interplay between personal hopes, social expectations, and financial uncertainty associated with urban life. Drawing on qualitative data from youth in tw

Studies of mining and urbanisation have been primarily conducted independently of one another, with limited consideration of the inter-linkages between the two. This analysis seeks to fill this gap by exploring the links between mining and urbanisation in a Ghanaian context. Ghana is an interesting case as it is both endowed with significant mineral wealth and is highly urbanised, with a long hist

Extractivism is a global phenomenon driven by the logic of capitalism that is manifested chiefly in mining, but also in agribusiness. Women around the world have emerged as leaders of resistance movements against extractivism. In this article, we question this recurrent theme in political ecology literature based on ethnographic fieldwork in southern Ecuador, where resistance has been less success

The preterite-present verb (ge)munan, meaning ‘to remember’ or ‘to be mentally active’, is attested throughout the Old English period (450-1150). Deriving from the Proto-Germanic preterite-present lexical verb munan, it belongs to a class of verbs many of which grammaticalised into modal auxiliaries during Old and Middle English. (Ge)munan itself appears to have undergone grammaticalisation, as su

The severity of the crisis in the Southern Eurozone countries is frequently attributed to inflated economies and reckless spending. Thus, it isn’t surprising that the main interpretation is that the crisis ought to be solved by decreasing government spending and lowering wages. This paper argues, instead, that one of the core underlying reasons for the severity of the crisis in the Southern Eurozo

Introduction: Occupational balance is an important concept in occupational therapy. However, no validated Occupational balance assessments currently exist in Lithuania. This study aimed to examine the psychometric properties of the Lithuanian version of the Occupational Balance Questionnaire 11 (OBQ11-LT). Method: A total of 127 healthy adults completed the OBQ11-LT to evaluate construct validity.

The IFMIF-DONES facility provides a very high intensity flux of neutrons for research on materials of future fusion reactors and other complementary applications. The generation of those neutrons is driven by stripping reactions between energetic deuteron particles and a liquid lithium jet. The requirements on the deuteron beam are to deliver a 40 MeV beam with a constant current of 125 mA. All th

Research assessing personality traits and religiosity across cultures has typically neglected variation across religious affiliations and has been limited to a small number of personality traits. This study examines the relationship between the Big Five personality traits and their facets, two theoretically distinct measures of religiosity, and twelve other personality traits across seven religiou

For quite some time, research across various fields has highlighted diversity as a critical factor in fostering creativity, knowledge generation, innovation, and entrepreneurship-at the levels of organizations, cities, regions, and entire countries. The aim of this book is to provide a comprehensive overview of the role of diversity in modern advanced economies, appealing to academics, researchers