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Objective. To investigate in a prospective study the relationship between age, pre-operative status, waiting time and post-operative outcome in patients assigned for unilateral total hip replacement (THR) due to osteoarthritis (OA). Method. One hundred and forty-eight patients (mean age 71 yr) with primary OA of the hip were investigated pre-operatively and 3, 6 and 12 months post-operatively with

Popular Abstract in Swedish Laser Doppler metoder avsedda för mätning av blodflöde baserar sig på det faktum att fotoner skiftar i våglängd när de träffar blodkroppar i rörelse. Den förändrade våglängden registreras och signalen bearbetas varefter resultatet uttrycks i en godtycklig enhet och anses utgöra ett mått på blodflöde. Laser Doppler Perfusion Monitoring (LDPM) är en metod med vilken blodThe operating principle of all laser Doppler methods is based on the fact that incident photons shift in wavelength when interacting with moving blood cells passing through the microvascular network. After photodetection and further signal processing, the recorded parameter can be considered an arbitrary measure of tissue blood flow, and this is referred to as ?perfusion?. Laser Doppler perfusion

This thesis concerns both design and optimization of NMR imaging systems and studies on non-thermal biological effects of electromagnetic fields. These two research fields are linked together by the fact that humans are subject to static and pulsed magnetic fields as well as to magnetic radio frequency fields (RF) during an NMR imaging investigation. This work bridges the gap between technology, p

In occupational therapy and occupational science, it is important to clarify the perspective from which the analysis of occupation is addressed. The purpose of this paper is to present a tentative structure for describing occupation, allowing for analysis in a lifelong panorama as well as for the immediate experience a person acquires from performing a single occupation. The concept of occupationa

Uniquely amongst vitamin K-dependent coagulation proteins, protein C interacts via its Gla domain both with a receptor, the endothelial cell protein C receptor (EPCR), and with phospholipids. We have studied naturally occurring and recombinant protein C Gla domain variants for soluble (s)EPCR binding, cell surface activation to activated protein C (APC) by the thrombin-thrombomodulin complex, and

This study presents 20 patients, randomised to receive either a collagen-treated or an ordinary Dacron graft for aortic reconstructions, and the results of a skin-prick test, blood parameters and ELISA for anti-collagen antibodies as well as NMR pictures during a 6 week follow-up period. Forty per cent (4/11) of those receiving a collagen impregnated graft had a significantly increased titre of an

The secosteroid hormone active vitamin D [1,25(OH)(2)D-3] is a key player in the regulation of calcium homeostasis and bone mineralization. In addition, it has antiproliferative and prodifferentiating effects on various cells in vitro and in vivo. The action of 1,25(OH)(2)D-3 is mediated through the vitamin D receptor (VDR), which belongs to the superfamily of steroid/thyroid hormone nuclear recep

Given electronic wave functions generated by the MCHF_CI program (LSJ format), this program calculates diagonal Lande a factors that determine separations of magnetic sublevels in weak external magnetic fields. In addition the program computes off-diagonal Lande factors and constructs the total interaction matrix for an atom in a magnetic field. By diagonalizing the interaction matrix and plotting

A new coated time-domain reflectometry (TDR) probe design is described and evaluated. In contrast to previous coated TDR probes, our probe may be used to measure both the dielectric constant (K-a) and bulk electrical conductivity (sigma(a)) in saline porous media. This was made possible by attaching two coaxial cables to a 0.27-m three-rod with a coated central rod. The shield of the first cable w

A comparison, based on a study of how time is treated, between three development tools for real time expert system is exposed. After a presentation of the tools, some of their advantages and disadvantages arepinpointed. Since these tools are only a partial answer to the problem of real time within the expert system's area, a standpoint concerning a good use of each tool is given.

Popular Abstract in Swedish Basic Fibroblast Growth Factor (bFGF) är en av flera tillväxtfaktorer som finns lagrad i benvävnaden. bFGF framkallar celldelning och tillväxt hos många olika celltyper, däribland benceller (osteoblaster) och broskceller. bFGF kan stimulera till nybildning av blodkärl och även benvävnad. I denna avhandling undersökes om utifrån tillfört bFGF kan öka benbildning och vävnBasic Fibroblast Growth Factor (bFGF) is one of the endogenous factors found in bone matrix. bFGF is a mitogen for many cell types, including osteoblasts and chondrocytes. It can stimulate angiogenesis and osteoblast gene expression. The purpose of this study was to investigate whether exogenous bFGF can stimulate the formation of bone in bone grafts and in a bone graft substitute. All experiments

In this article, we attempt to develop a meta-language for a relational approach to urban walking that is able to account for walking as a mutable, embodied, materially heterogeneous and distributed activity. Following the perspective on walking as developed in a series of articles by Jennie Middleton, we develop a notion of the walker as a socio-technical assemblage. By recognising walking as an

Synapsins are a family of phosphoproteins that modulate the release of neurotransmitters from synaptic vesicles. The release of insulin from pancreatic beta-cells has also been suggested to be regulated by synapsins. In this study, we have utilized a knock out mouse model with general disruptions of the synapsin I and II genes [synapsin double knockout (DKO)]. Stimulation with 20 mM glucose increa

Children born after assisted reproductive technologies (ART) have an increased morbidity. The risk of developing cerebral palsy is nearly doubled and the risk of developing epilepsy is also higher. Behavioural problems including attention deficit/hyperactivity disorder may be more common in children born following ART than among naturally conceived children but the finding is uncertain. Data on au