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India and Pakistan are entrenched in an antagonistic relation that is constantly on the verge of, once more, developing into an armed conflict. There are, presently, no signs of conciliatory initiatives on the level of state-to-state interactions, which, contrariwise, tend to uphold incompatible conceptions of regional order, nationhood and the Partition as a constitutive moment. The latter furthe

In this paper, we study rational Collet–Eckmann maps for which the Julia set is not the whole sphere and for which the critical points are recurrent at a slow rate. In families where the orders of the critical points are fixed, we prove that such maps are Lebesgue density points of hyperbolic maps. In particular, if all critical points are simple, these maps are Lebesgue density points of hyperbol

Variable selection properties of procedures utilizing penalized-likelihood estimates is a central topic in the study of high-dimensional linear regression problems. Existing literature emphasizes the quality of ranking of the variables by such procedures as reflected in the receiver operating characteristic curve or in prediction performance. Specifically, recent works have harnessed modern theory

Time-resolved fluorescence spectroscopy is used increasingly to probe molecular motions at the aqueous interfaces of biological macromolecules and membranes. By recording the time variation of the fluorescence frequency, thermal atomic fluctuations in the vicinity of the chromophore can be probed. From such fluorescence Stokes shift (FSS) experiments, it has been inferred that water motions in the

Antibody-based microarrays are among the novel classes of rapidly evolving proteomic technologies that holds great promise in biomedicine. Miniaturized microarrays (< 1 cm(2)) can be printed with thousands of individual antibodies carrying the desired specificities, and with biological sample (e.g., an entire proteome) added, virtually any specifically bound analytes can be detected. While consumi

Immune complexes were formed in vitro with antibodies obtained from rabbits immunized with bovine serum albumin in Freund's complete (FCA) or incomplete (FIA) adjuvant. The antibodies were mixed with different amounts of antigen. Immune complexes formed at maximum precipitation proportions were efficient in complement activation, whereas immune complexes formed at antigen excess had weak complemen

Numerous microscopic studies of coccidian oocysts from avian feces have become the basis for species identification. In contrast, molecular studies of wild birds' Coccidia are still in their infancy and are mostly based on DNA extracted from the blood stages of these parasites. Linking microscopic and molecular data requires a method that reliably extracts DNA from single oocysts with parallel det

Approximately 800 genes coding for seven-transmembrane, G-protein-coupled receptors have so far been recognized. In spite of this, many of these receptors are defined by their sequence only, and are therefore classified as orphan receptors. Without knowing what their endogenous ligands are, we lack the information needed to understand their physiological role and hence cannot make use of them as d

In a number of autoimmune diseases, for example, rheumatoid arthritis and systemic lupus erythematosus, it is known that autoantibodies are present before the clinical onset. Recently we have shown that autoantibodies can be found many years before symptom onset in primary Sjögren's syndrome. This implies that screening for autoantibodies may be used to identify individuals at risk of developing s