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Evidence for supercritical mixing layers in the ECN Spray A

Prior work on an engine combustion network Diesel fuel injector led to the conclusion that under Diesel engine conditions (combustion chamber pressure and temperature) the jet was transitionally supercritical; meaning that the core of the jet would be condensed liquid while the edge of the jet would be supercritical. We report initial experiments aimed at observing the thickened turbulent mixing l

Vaccination against atherosclerosis? Induction of atheroprotective immunity

Atherosclerosis involves the formation of inflammatory arterial lesions and is one of the most common causes of death globally. It has been evident for more than 20 years that adaptive immunity regulates the magnitude of the atherogenic proinflammatory response. T cells may also influence the stability of the atherosclerotic lesion and thus the propensity for thrombus formation and the clinical ou

Bronchial healing, lung parenchymal histology, and blood gases one month after transplantation of lungs topically cooled for 2 hours in the non-heart-beating cadaver

BACKGROUND: The aim of this study was to investigate, in an experimental survival model, the functional and morphologic results of lung transplantation using lungs from non-heart-beating donors. METHODS: Left lungs, topically cooled to 25 degrees C for 2 hours in situ after 5 minutes of circulatory arrest followed by 26 minutes of unsuccessful cardiopulmonary resuscitation, were transplanted into

Evaluation of a colorimetric assay based on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) for rapid detection of rifampicin resistance in Mycobacterium tuberculosis

OBJECTIVES: To standardise the colorimetric assay based on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) for the rapid detection of rifampicin-resistant Mycobacterium tuberculosis in clinical practice and to evaluate the assay on a collection of 92 clinical isolates. DESIGN: The Bactec method was used as the reference method. Rifampicin was used for the susceptibility testing

Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism.

Several findings link proteinase 3 (PR3) to small vessel vasculitis. Besides being a major target of anti-neutrophil cytoplasm antibodies (ANCA), previous findings have shown increased circulating levels of PR3 in vasculitis patients, increased levels of neutrophil membrane-PR3 (mPR3) expression and a skewed distribution of the − 564 A/G polymorphism in the promotor region of the PR3 gene. In this

Profound inhibition of chronic itch induced by stimulation of thin cutaneous nerve fibres.

Background Despite the fact that severe itch is common in many dermatological diseases, the therapeutic arsenal against itching is limited. From neurophysiological experiments, using a new technique termed cutaneous field stimulation, it is known that acute itch can be effectively relieved by stimulation of cutaneous nociceptors. Methods We tested the effects of cutaneous field stimulation (25 mi

Nonprofit Organizations Shaping the Market of Supplies

In the humanitarian aid context, the availability of essential commodities in the right quantities and at the right time and place is crucial for the survival of beneficiaries. In order to avoid the risks associated with a limited supplier base, non-profit organizations are increasingly becoming aware of the need to diversify their supply base and to include the for profit, or corporate sector. Si

Up-regulation of endothelin receptors induced by cigarette smoke--involvement of MAPK in vascular and airway hyper-reactivity.

Cigarette smoke exposure is well known to cause cardiovascular and airway diseases, both of which are leading causes of death and disability in the world. However, the molecular mechanisms that link cigarette smoke to cardiovascular and airway diseases are not fully understood. Vascular and airway hyper-reactivity plays an important role in the pathogenesis of cardiovascular and airway diseases. R

Healing or dealing? Neospiritual Therapies and Coaching as Individual Meaning and Social Discipline in Late Modern Swedish Society

This book chapter examines the rapidly expansion of various neospiritual and science-like practices currently mobilized in late modern Swedish pursuits of identity, meaning, and health. The focus is on the emergence and marketing of new entrepreneurs who have established themselves as “therapists” or “coaches”, promoting personal development, and how they organize their own systems of training and

Binary Statistics from Hipparcos

Book abstract: The book reviews recent observations of non-evolved and evolved binary populations in clusters and the field with special emphasis on statistical biases, incompleteness and distribution functions. Different binary types are considered: cataclysmic variables, super-soft X-ray sources, double degenerate binaries, Algol-type binaries, Be binaries, X-ray binaries, and Wolf-Rayet binarie

The environment and the origins of islet autoimmunity and Type 1 diabetes.

Type 1 diabetes involves the specific destruction of the pancreatic islet β-cells, eventually resulting in a complete dependency of exogenous insulin. The clinical onset of diabetes is preceded by the appearance of autoantibodies against β-cell antigens. The human leukocyte antigen (HLA) region is the single most important genetic determinant of Type 1 diabetes susceptibility, yet variability in t

Excited state and charge photogeneration dynamics in conjugated polymers

Conjugated polymers are becoming interesting materials for a range of optoelectronic applications. However, their often complex electronic and structural properties prevent establishment of straightforward property-function relationships. In this paper, we summarize recent results on the photophysics and excited state dynamics of conjugated polymers, in order to paint a picture of exciton formatio

The loss of a spirit: Metaphor and practice in Aymara decolonization

This paper explores the bearing had by Aymara notions of spirit loss on contemporary indigenous discourses of colonialism and decolonization and discusses the dynamics of cross-fertilization between “traditional” curing practices and cosmology on the one hand and indigenous ethnopolitical activism and discourse on the other.

Altered Consciousness in Religion

Mysticism can be regarded as an integral element of religion. It includes both a way of life and a direct consciousness of the presence of God. Broadly defined as such, one can encounter mystical dimensions within all religions of the world. In order to alter consciousness, mystics in different traditions use a variety of techniques – different types of meditation, visualisation, repetitive prayer

On the Spiral Structure of NGC 5248: An Analytic Approach

An improved nonlinear asymptotic theory of spiral density waves is developed. It extends the theory developed by Yuan & Kuo to a global theory, not just one limited to the vicinity of the resonance. It can then be applied to the recent high-resolution observations of CO and HST NICMOS of nearby spiral galaxies. As an example, we apply the theory to the nearby grand-design spiral galaxy NGC 524

Thin and Thick Disk Results for α-, r- and s-Process Elements

We present the first results from several ongoing studies of the stellara bundances, ages, and chemical trends in the long-lived dwarf stars in the solar neighborhood that belong to the thin and thick galactic disk.We confirm that the trends of α-elements in the thin and thick disk are distinct, and we also find that the thick disk show the typical signature of SN Ia contribution to the chemical e