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Aggregation in a protein-surfactant system. The interplay between hydrophobic and electrostatic interactions

By precipitating a complex salt Ly(OS)(8) of the positively charged protein lysozyme and the anionic surfactant octyl sulfate OS-, one can generate a true ternary system: water-Ly(OS)(8)-NaOS. Using NMR diffusometry and U spectroscopy measurements the thermodynamic parameters of the association processes have been determined. The solubility product of the complex salt, K-s, is 10-(28) M-9.(1) On a

Competitive Na+ and Rb+ binding in the minor groove of DNA

Sequence-dependent coordination of alkali ions to the nucleotide bases in the minor groove of AT-tract B-DNA has recently been inferred from X-ray crystallography, solution NMR and computer simulations. Here, we present new Na-23 and Rb-87 magnetic relaxation dispersion (MRD) data that demonstrate competitive and long-lived binding of Na+ and Rb+ ions in the minor groove of the B-DNA duplex [d(CGC

Alternative food systems and the citizen-consumer

Ethically informed and committed consumers are crucial to the functioning of many alternative food systems. These consumers are poorly understood, though, and their common description as informed and democratically minded finds little resemblance to the real world. Few individuals fit the ideal of the concept of the so-called citizen-consumer. This commentary therefore argues that both researchers

Multi-modal visual experience of brand-specific automobile design

Purpose – This paper presents a questionnaire study of brand-specific perceptions of automotive design using subjective rating methods. The purpose of the paper is to explore the multiple modalities of the visual product experience of automobile design as perceived by the general public. Furthermore, the experiences were analysed using a framework for visual product experience (VPE). Design/method

Distribution of the maximum in air pollution fields

Air quality standards are set to protect public health. The values of the standards are often based on health effect studies, without any statistical considerations. In order to judge if a standard is met measurements of ambient air quality are taken at monitoring stations, and these measured values are used to decide whether or not the standard has been violated. In this paper we examine the stat

The effect of a new treatment based on somatosensory stimulation in a group of patients with somatically related tinnitus.

The aim of this study was to evaluate the effect of a new treatment consisting of stretching, posture training, and auricular acupuncture immediately and at a 3-month followup. This method has not been tested previously. From an original pool of 41 potential subjects, we recruited 24 (12 men, 12 women; ages 18-70 years) into this study and divided them from a waiting list into either a treatment g

Increased litter size and super-ovulation rate in congenic C57BL mice carrying a polymorphic fragment of NFR/N origin at the Fecq4 locus of chromosome 9.

By analysing N2 mice from a cross between the inbred C57BL strain B10.Q and the NMRI-related NFR/N strain, we recently identified a quantitative trait locus (QTL) influencing litter size. This locus is now denoted Fecq4, and it is present on the murine chromosome 9. In the present paper, we describe how the Fecq4 fragment originating form the NFR/N mouse strain will affect B10.Q mice by means of b

High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma.

The childhood cancer neuroblastoma arises in the developing sympathetic nervous system and is a genotypically and phenotypically heterogeneous disease. Prognostic markers of poor survival probability include amplification of the MYCN oncogene and an undifferentiated morphology. Whereas these features discriminate high- from low-risk patients with precision, identification of poor outcome low- and

The amateur scientist's spectrophotometer

This chapter describes the construction and performance of a spectrophotometer that is very easily constructed from a DVD, a digital camera, a lamp and some cardboard, wood, and sheet metal.

Control strategy for the adaptive optics of the Euro50

The scheme presently envisaged for the EURO50 adaptive optics ispresented. The Euro50 adaptive optics will primarily work with laserguide stars (LGSs) and control of either one or two deformable mirrors(SCAO and DCAO respectively), but operation using a natural guide star(NGS) is also foreseen. The point spread function (PSF) for SCAOoperation using a single NGS is evaluated. An algorithm for opti

Sweden - Cultural and Institutional Dimensions of Developing and Reforming Social Security Systems

The paper gives a brief presentation of the cultural and institutional specificities of Sweden and how these cultural and institutional specificities impact the development of the Swedish social welfare system over periods of change, transition and strategic adjustment. The paper concludes by presenting a suggestion of a new view of the relationship between culture and social welfare systems, whic