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A realist conceptualization for studying information system development methodology

It is tempting to assume that Information Systems Development Methodology (ISDM) is clearly understood because it has attracted researchers across a range of research fields offering a rich set of descriptions and explanations of ISDM. Although there are considerable studies on ISDM, this paper argues that different disciplinary interests have resulted in fragmented assessments. Consequently, this

A Charter Moment: Restructuring Governance for Sustainability

We are living in a highly dynamic, human-dominated Earth System in which non-linear, abrupt and irreversible changes are not only possible but also probable. These changes require institutional structures capable of steering human society away from critical tipping points and irreversible change and ensuring sustainable livelihoods for all. We see 2012 as a charter moment, a historic opportunity t

A Gaussian mixture model for time-frequency analysis during atrial fibrillation electrocardiograms

During atrial fibrillation (AF), time-frequency analysis of atrial signal has been applied to describe fibrillatory frequency trends. Recently, temporal changes in spectral shape have been investigated using the spectral profile technique. This profile is computed recursively by fitting each short-time log-spectrum to a spectral template, using amplitude scaling and frequency shifting. The purpose

Complex Formation of Small Molecules during Isolation in Low Temperature Matrices: Water Dimers in p-H-2 and Ne Matrices

The concentrations of water dimer are compared in Ne and p-H-2 matrices at low temperatures, using infrared spectroscopy. Additional data are given for o-D-2 and Ar matrices. For a given monomer concentration, the dimer concentration is significantly higher in solid Ne (or Ar) than in solid p-H-2. In p-H-2, the dimer concentration is only slightly higher than expected for a random distribution of

Storm-water management in Malmö and Copenhagen with regard to climate change scenarios

Aktuell status för dagvattenhantering i grannstäderna Köpenhamn och Malmö studerades med avseende på befintliga åtgärder och genomförda systemen i de båda städerna. Tillämpning av blå-gröna lösningar i de yttre delarna av Malmö började på 1990-talet och följaktligen är samarbete mellan olika avdelningar inom kommunen mer strukturerat i Malmö medan processen i Köpenhamn fortfarande är baserad på trThe current status of storm-water management in the neighbor cities of Copenhagen and Malmö was studied with respect to present measures and the implemented systems in both cities. Application of blue-green solutions in the outer parts of Malmö started in the 1990s; hence collaboration between different departments in the municipality is more structured in the city of Malmö while in Copenhagen the

Dersim : A Century of State-Led Destruction and Resistance

What happened in Dersim in 1937–38, in the early years of the Turkish Republic, is no longer a secret. In recent decades, Dersim has been recognised as at least a state-led “massacre”, mass graves have been discovered, and written and oral testimonies of both victims and perpetrators have come to light. However, a clear definition and recognition of this genocide, as well as reconciliation and res

Cerebrospinal fluid platelet-derived growth factor receptor-beta is negatively correlated with depressive symptom severity in suicide attempters

Background: Depression and suicidal behavior have been linked to increased blood-brain barrier (BBB) permeability. Platelet-derived growth factor receptor beta (PDGFR-β) is widely expressed in pericytes and promotes BBB integrity. Here, we investigated cerebrospinal fluid (CSF) levels of PDGFR-β in suicide attempters and healthy controls and correlated PDGFR-β to depression symptom severity. Metho

Sickle cell retinopathy. A focused review

Purpose: To provide a focused review of sickle cell retinopathy in the light of recent advances in the pathogenesis, multimodal retinal imaging, management of the condition, and migration trends, which may lead to increased prevalence of the condition in the Western world. Methods: Non-systematic focused literature review. Results: Sickle retinopathy results from aggregation of abnormal hemoglobin

(Re)constructing a Deeply Divided Society: Peacebuilding Lessons from Bosnia and Herzegovina

In this thesis I have discussed the possibility of building a stable and long-lasting peace in a state whose society is considered to be deeply divided ? Bosnia and Herzegovina. The main question to be answered by this study was Which factors facilitate and which factors obstruct stable and long-lasting peace in a deeply divided society? I have examined the post-war constitutional design of Bosnia

Simulation of charged colloids in solution

Physicochemical properties of solutions of charged colloids are often dominated by the electrostatic interactions present in such systems. A full determination of these properties constitutes a highly nontrivial many-body problem involving long-range interactions. In electrostatically strongly coupled systems, it is essential to explicitly include both the charged colloids and the small ions in th

Reactivity of iso-diiodomethane and iso-iodoform, isomers of CH2I2 and CHI3, toward the double bond of a variety of cycloalkenes

The metastable CH2I-I and CHI2-I isomers formed by UV photolysis of CH2I2, and CHI3 transfer methylene and iodomethylene groups, respectively, to a variety of cycloalkenes, leading to their cyclopropanation. More than a 100-fold increase of the reaction rate with increasing solvent polarity suggests a dipolar transition state. The fastest second-order rates observed were in CH3CN. However, CH2Cl2

Collaboration in the Absence of Communication

On a software development project many people collaborate to build a product contributing different pieces of the final product. Often people on a development team will work in parallel, either on different parts or on the same parts of the product, and follow processes to co-ordinate their work with other people on the team. When teams are distributed this co-ordination becomes more difficult sin

Interaction assessments in correlated and autocorrelated environments

Natural food webs are embedded in a variable environment, which causes population densities to fluctuate, despite a potential stable equilibrium. Population interactions as well as the characteristics of the environmental fluctuations determine the resulting population dynamics. Populations sensitive to the same kind of environmental disturbances will show correlated responses in their respective

Ideation and ability: When actions speak louder than words

We present an approach and examples of design artefacts from on-going work on how children with profound disa-bilities can participate in formative design processes. It involves the pedagogical use of digitally interactive mul-tisensory environments. Rather than mimic participatory design from more symmetrical contexts, we address po-tentials in the situation at hand as well as the key issues of v

Towards Linking Disruptive Innovations and BOP Markets

The base of the world economic pyramid consists of 4 billion people typically earning less than 4 USD per day. This population is generally called the base of the pyramid (BoP). Much research on BoP markets focuses on motivating companies to enter these markets to create a win-win situation such that companies can gain benefits and BoP customers can satisfy their unmet or under-served needs. The r