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Functionally distinct subsets within the T-helper (CD4+) cell population have been described in man, rat and mouse. We have shown previously that the CD4+ 45R- human lymphocytes are producers of IL-2 within 24 hr of polyclonal stimulation and are the major interferon (IFN) producers. The mAbs 4B4 (CDw29) and Leu 8 (p80) are here used together with Leu-18 (CD45R) to characterize the subpopulations

Protein D, a surface-exposed 42-kDa membrane lipoprotein, is well conserved among both type b and nontypeable Haemophilus influenzae strains, and it is considered a vaccine against H. influenzae infections. Here, we report the large-scale purification of a nonacylated form of protein D (PDm) from the periplasmic space of Escherichia coli overexpressing PDm. Screening of human sera for levels of an

Dampness in buildings has been linked to adverse health effects, but the specific causative agents are unknown. Mycotoxins are secondary metabolites produced by molds and toxic to higher vertebrates. In this study, mass spectrometry was used to demonstrate the presence of mycotoxins predominantly produced by Aspergillus spp. and Stachybotrys spp. in buildings with either ongoing dampness or a hist

Natural killer (NK) T lymphocytes are a subpopulation of T lymphocytes regarded as early regulators of immune responses. The majority of NKT cells are restricted by the CD1d molecule. NKT cells have mostly been studied in one single mouse strain, C57BL/6 (B6), because of the absence of NK1.1 in other common mouse strains, and the lack of other reliable surface markers for CD1d-restricted cells. To

An NMR technique to measure exchange kinetics at thermal equilibrium in dispersions of moderately soluble crystalline material is presented. By monitoring the exchange of molecules between pools in solid and dissolved form, one can characterize the surface specific exchange rate. Illustrative experiments were performed in a model system with beta-type crystals of tripalmitin as the solid phase and

The susceptibility pattern of Mycobacterium marinum was determined. Quinupristin-dalfopristin and telithromycin were less active than clarithromycin. Linezolid showed good antimicrobial activity at clinically achievable concentrations. Gatifloxacin, levofloxacin, and moxifloxacin displayed activities similar to those of ciprofloxacin. Gemifloxacin was less active. The Etest method showed variable

A novel gel structure called the "plum-pudding" gel was described by us previously. I The gel was composed of randomly dispersed microgel particles ("plums") in a conventional hydrogel network. Depending on the preparation conditions, the microgels can be incorporated into the gel as expanded networks or dense collapsed globules. Where the microgel particles exist as collapsed globules, they have

Concentrations of 34 trace elements in hair have been determined in 47 females from an acid region in southern Sweden, who were compared with 43 females from an alkaline area. The concentrations of these elements in hair and drinking water were determined by inductively coupled plasma optical emission spectroscopy and inductively coupled plasma mass spectrometry. The hair concentrations of boron a

C4b-binding protein (C4BP) is best known as a potent soluble inhibitor of the classical and lectin pathways of the complement system. This large 500kDa multimeric plasma glycoprotein is expressed mainly in the liver but also in lung and pancreas. It consists of several identical 75kDa α-chains and often also one 40kDa β-chain, both of which are mainly composed of complement control protein (CCP) d

Summary: The maturation of B-lymphoid cells from hematopoietic stem cells in the bone marrow is a complex process under control of interplay between extrinsic and intrinsic factors. In addition to serving as a model for normal cell differentiation, disturbances in this process results in immunodeficiencies and malignancies, such as leukemia and lymphoma, making the subject of high relevance for mo

The aim of this chapter is to provide researchers with a tool kit of semi-experimental and experimental techniques for studying code-switching. It presents an overview of the current off-line and on-line research techniques, ranging from analyses of published bilingual texts of spontaneous conversations, to tightly controlled experiments. A multi-task approach used for studying code-switched sente

PURPOSE: To evaluate the long-term results of a prospective, longitudinal case series of untreated, traumatic triangular fibrocartilage complex (TFCC) tears found in displaced distal radial fractures. METHODS: Between 1995 and 1997, 51 patients (24 men, 27 women; age, 20-57 y) with a displaced distal radius fracture had wrist arthroscopy to identify associated injuries. Forty-three patients had c

Background: Evidence-based guidelines should in most cases be followed also in the treatment of elderly. Older people are often suboptimally treated with the recommended drugs. Objectives: To describe how well general practitioners adhere to current guidelines in the treatment of elderly with cardiovascular disease and evaluate local education as a tool for improvement. Method: Data was colle

In this chapter, the advantages and disadvantages of 3D fast spin echo (FSE) pCASL as a measure of brain tumor perfusion are reviewed. In addition, we compare pCASL with other perfusion techniques and discuss future ASL approaches. A prospective study of 28 patients with contrast-enhancing brain tumors was performed at 3 T using dynamic susceptibility contrast (DSC) MRI and pCASL. The visual quali

Abstract in UndeterminedThis article discusses the staff’s view on dementia and its impact on the care delivered arising outof a qualitative comparative study focusing on long-term care of older people in France, Portugaland Sweden. The aim was to explore the staff’s view on the illness dementia; on older peoplesuffering from dementia; the care provided and the impact of various views on the care.

Abstract is not available