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Within the homologous series of amphiphilic peptides AnK, both A8K and A10K self-assemble in water to form twisted ribbon fibrils with lengths around 100 nm. The structure of the fibrils can be described in terms of twisted β-sheets extending in the direction of the fibrils, laminated to give a constant cross section of 4 nm by 8 nm. The finite width of the twisted ribbons can be reasonably explai
Long term multiple systemic antibiotics form the cornerstone in the treatment of bone and joint tuberculosis, often combined with local surgical eradication. Implanted carriers for local drug delivery have recently been introduced to overcome some of the limitations associated with conventional treatment strategies. In this study, we used a calcium sulphate hemihydrate (CSH)/nanohydroxyapatite (nH
Under de senaste åren har västeuropeiska bedömare uttryckt oro över utvecklingen i Ungern och Polen. En ny spricka mellan Väst- och Östeuropa har tagit form, vilket märktes till exempel i samband med valet till Europaparlamentet förra året. Inte minst uppfattas Ungerns premiärminister Viktor Orbán och Frankrikes president Emmanuel Macron som representanter för ett östligt, bakåtblickande respektiv
The Ålandic autonomy has evolved into a relatively well-functioning system over the last century. A scrutiny of the first three decades following the decisions by the Council of the League of Nations shows that this was not always the case. This article engages with the main political issues that Åland faced during this time, focusing on the problems that directly or indirectly involved the League
BACKGROUND: There is little consensus on a standard approach to analysing bone scan images. The Bone Scan Index (BSI) is predictive of survival in patients with progressive prostate cancer (PCa), but the popularity of this metric is hampered by the tedium of the manual calculation. OBJECTIVE: Develop a fully automated method of quantifying the BSI and determining the clinical value of automated
In the present investigation, we sought to refine the classification of urothelial carcinoma by combining information on gene expression, genomic, and gene mutation levels. For these purposes, we performed gene expression analysis of 144 carcinomas, and whole genome array-CGH analysis and mutation analyses of FGFR3, PIK3CA, KRAS, HRAS, NRAS, TP53, CDKN2A, and TSC1 in 103 of these cases. Hierarchic
Popular Abstract in Swedish Immunförsvaret har till uppgift att skydda kroppen mot främmande mikroorganismer såsom bakterier och virus. En rad olika celler, vävnader samt organ samarbetar för att utforma ett väl fungerande immunförsvar. Det är ytterst viktigt att immunförsvaret känner igen kroppsfrämmande ämnen (antigen), som till exempel bakterieceller, men också att det skiljer dessa från kroppsGeneration of long-lived plasma cells and memory B cells of high affinity takes place in germinal centers and depends on help from a specialized CD4+ T cell subset termed T follicular helper (Tfh) cells. These processes are crucial for long-term protection upon natural infection or in settings of vaccination, however they are also responsible for development of antibody-mediated autoimmune disease
A search for a heavy Standard Model Higgs boson decaying via H -> ZZ -> l(+)l(-)q (q) over bar, where l = e, mu, is presented. The search is performed using a data set of pp collisions at root s = 7 TeV, corresponding to an integrated luminosity of 1.04 fb(-1) collected in 2011 by the ATLAS detector at the CERN LHC collider. No significant excess of events above the estimated background is found.
This paper makes a distinction between three theoretical frameworks that have been highly influential in the discourse on innovation, competitiveness and sustainability: sectoral systems of innovation (SSI), technological innovation systems (TIS) and socio-technical systems (ST-Systems). These frameworks share a common systems approach to innovation but are often positioned as different bodies of
The large difference between the Planck scale and the electroweak scale, known as the hierarchy problem, is addressed in certain models through the postulate of extra spatial dimensions. A search for evidence of extra spatial dimensions in the diphoton channel has been performed using the full set of proton-proton collisions at root s = 7 TeV recorded in 2011 with the ATLAS detector at the CERN La
Human rights values are often mentioned politically in the interaction between the Americas and Europe, but their scholarly examination remains rare. This paper aims to contribute to the study of Latin America and Europe today by re-examining the engagement of the European Union and Mexico, extending beyond trade to encompass human rights concerns. While the Mexico-European Union relationship cont
In this study we explored how mindfulness training interacted with psychological wellbeing and compassion for children in early adolescence. The sample included 251 7th and 8th grade students from two elementary schools in southern Sweden. The intervention was a mindfulness based-program called COMPAS (Compassion and Attention in the Schools), which consisted of two pre recorded guided meditations
Problem: Literature yields ambiguous results regarding the effectiveness of the business incubators’ role as network intermediaries, which is reflected in the varying networking behavior of entrepreneurs. Network expectations as a driver for the networking behavior of entrepreneurs have not been studied within this context and present a void in current literature. Purpose: This study seeks to exp
The current thesis critically investigates whether training and using third-party data in artificial neural networks (ANNs) could constitute a liability for copyright infringement. Furthermore, the present paper sets out to explore whether training and using ANNs could fall within the IP right holders' exclusive rights. In this regard, this thesis will mainly focus on the reproduction parts as
Given the assumptions of rational choice, this essay explicates the distributive consequences of different ethical positions and how the relationship between eth-ics and distributions provides a rationale for a struggle for moral authority for the purpose of procuring distributive shares. The argument provides a partial answer to the question of why there is political struggle in all human societi
Tourism has recently been acknowledged as a potential means for sustainable development. This study examined what tourism has meant for the community members involved in community based tourism (CBT) projects in rural Quintana Roo, Mexico, with regards to the sustainable development of their communities. The study used a qualitative case study research design to compare two different approaches to
Background. Tissue transglutaminase (tTG) autoantibodies are serological markers for celiac disease. The aim was to study the efficacy of the pTnT-rhtTG plasmid and subsequent diagnostic accuracy of tTG autoantibodies for childhood celiac disease using radioligand binding assays. Methods. Coupled in vitro transcription and translation of tTG were performed by pTnT-rhtTG as well as by the pGEMt Eas
