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Insulin Dependent Diabetes Mellitus (IDDM) is a chronic disease characterized by the inability of the pancreas to produce sufficient amounts of insulin. Daily compensation of the deficiency requires 4-6 insulin injections to be taken daily, the aim of this insulin therapy being to maintain normoglycemia- i.e., a blood glucose level between 4-7 mmol/L. To determine the quantity and timing of these

When Swedish wastewater treatment plants were rebuilt to include enhanced nitrogen removal, anaerobic ammonium oxidation (anammox) was far from being a mature technology. During the 2000s, the process has been introduced into sludge liquor treatment worldwide. The step to introduce anammox in the mainstream is decreasing, but lab- and pilot-scale studies on real municipal wastewater are yet lackin

The purpose of this study was to explore neuroretinal transplantation in a large animal model of severe retinitis pigmentosa and to establish graft development, long-term survival, graft-host integration, and effects on the host retina. Methods Rhodopsin transgenic pigs, aged 6 months, received in one eye a fetal full-thickness neuroretinal sheet in the subretinal space by means of vitrectomy and

Public procurement for innovation is a matter of using public demand to trigger innovation. Empirical studies have demonstrated that demand-based policy instruments can be considered to be a powerful tool in stimulating innovative processes among existing firms. However, the existing literature has not focused on the role this policy instrument can play in the promotion of (knowledge-intensive) en

The aim of the work presented here was to provide enhanced assessment methods that are able to prove higher load carrying capacities and longer service lives for existing concrete railway bridges. One main objective was to develop methods for non-linear analysis since this provides the greatest potential to discover any additional sources for load carrying capacity, and gives an improved understan

Direkt Profil is an automatic analyzer oftexts written in French as a second lan-guage. Its objective is to produce an eval-uation of the developmental stage of stu-dents under the form of a grammaticallearner profile. Direkt Profil carries outa sentence analysis based on developmen-tal sequences, i.e. local morphosyntacticphenomena linked to a development in theacquisition of French.The paper pre

By using an integrated dynamic model we are able to reconstruct the supply and gold price of the past (1920-2010) and this is used to predict the future supply of gold to the market and to make a forecast of the goldprice 2010-2100. The model was validated against field data for the period 1920-2010 and it performs well. The model GOLD is implemented in the STELLA® software and the model described

Full-scale ethanol production from spruce has been evaluated, mainly from an energy perspective, using an Aspen Plus-model including all major process steps. The model input was based on data recently obtained on lab scale or in a process development unit. A number of different process configurations are presented in order to demonstrate how heat integration within the ethanol process significantl

Popular Abstract in Swedish Bakgrund Alzheimers sjukdom (AD) är den vanligaste formen av demenssjukdom och svarar för ca 60 % av dessa patienter. Sjukdomen har en smygande debut och den sjukliga processen i hjärnan börjar troligen decennier innan den ger kliniska symptom som försämrat minne och organisationsförmåga, språksvårigheter, problem med tidsuppfattning och orientering. Även förmågan att uBackground Prospective longitudinal studies in Alzheimer's disease (AD) that include cholinesterase inhibitor (ChEI) treatment in routine clinical settings are scarce. The patients vary in severity of the disease, clinical course, rate of progression and response to treatment. Knowledge about the predicted course of the disease, sociodemographic and clinical factors affecting the outcome and the i

During recent decades we have witnessed growing scientific concern, public debate and media attention concerning the possible adverse effects on humans and wildlife that may result from exposure to a wide range of environmental contaminants. These contaminants are called endocrine disrupters, or endocrine-disrupting compounds (EDCs) and are defined as chemicals that interfere with the function of

Radionuclides from the Chernobyl accident were released and dispersed during a limited period of time, but under different weather conditions. As a result the radionuclides were unevenly distributed on the ground. During the years the initial deposition has been altered at some locations by different processes, but remains relatively unchanged in others. Here we report on the current inhomogeneous

Deficiencies of the early components of the classical complement pathway impair the actions of innate and humoral immunity and may lead to increased susceptibility to infections. We have studied the genetic basis of total C4B deficiency in a Finnish patient with recurrent meningitis, chronic fistulas and abscesses. The maternal chromosome carried a four-gene deletion including the C4B gene, and a