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Ethical Considerations in Nutrigenetics and Nutrigenomics

Ethics is the study of the normative dimensions of human relations and experiences. This chapter discusses such questions in relation to basic values in modern society. The normative foundations for the analysis are the values of human dignity, autonomy, freedom, equality, and solidarity, as well as the responsibilities of society toward its citizens, including freedom, security, and justice. The

Utgrävningarna av gravfältet i Vätteryd

Mellan åren 1955 och 1957 utförde Märta Strömberg (sedermera professor i arkeologi) och Rolf Petré (som senare blev fil. lic. i arkeologi) arkeologiska undersökningar av Vätterydsgravfältet i norra Mellby socken (L1990:1893 / Norra Mellby 1:1) ...

MULTIDISCIPLINARY ASSESSMENT OF A YEAR 2035 TURBOFAN PROPULSION SYSTEM

A conceptual design of a year 2035 turbofan is developed and integrated onto a year 2035 aircraft model. The mission performance is evaluated for CO2, noise and NOx and is compared with a notional XWB/A350-model. An OGV heat exchanger is then studied rejecting heat from an electric generator, and its top-level performance is evaluated. The fan, the booster and the low-pressure turbine of the propu

Acute and long-term efficacy and safety with a single cryoballoon application as compared with the standard dual application strategy : a prospective randomized study using the second-generation cryoballoon for pulmonary vein isolation in patients with symptomatic atrial fibrillation

Aims: A single cryoballoon (CB) application per vein for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF) could save time and was therefore compared to the standard approach of two consecutive CB applications for acute and long-term efficacy and safety.Methods and results: Patients with symptomatic AF were randomized to a single CB application per vein guided by an Achieve®

Changes in protein tyrosine phosphorylation in the rat brain after cerebral ischemia in a model of ischemic tolerance

A brief period of sublethal cerebral ischemia, followed by several days of recovery, renders the brain resistant to a subsequent lethal ischemic insult, a phenomenon termed ischemic preconditioning or tolerance. Ischemic tolerance was established in the rat two-vessel occlusion model of ischemia, induced by occlusion of both carotid arteries in combination with hypotension. Ischemic preconditionin

Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning

A short period of sublethal preconditioning ischemia (3 min) followed by two days of reperfusion provides almost complete protection against ischemic cell death induced by a second (9 min) lethal ischemic episode. Here, we have investigated the extracellular signal-regulated protein kinase kinase and extracellular signal-regulated protein kinase, two kinases known to activate gene transcription an

Protection against ischemia-induced neuronal damage by the α2-adrenoceptor antagonist idazoxan : influence of time of administration and possible mechanisms of action

The protective effect of the α2-receptor antagonist idazoxan against neuronal damage in the neocortex and in the hippocampal CA1 region was studied in rats exposed to 10 min of incomplete forebrain ischemia. When administered i.v. immediately after ischemia (0.1 mg/kg) and subsequently for 6 h (10 μg/kg/min), idazoxan significantly reduced neuronal damage in the hippocampus (from 84 to 26%) and in

Climate City Contracts? Governing towards Climate Neutral Cities

Climate City Contracts or CCCs are being developed in the context of a larger mission, with many stakeholders, funding, and growing momentum, hopefully providing a new force, legitimacy, and inspiration to ongoing urban climate actions. CCCs differ from current strategies for tackling climate change in cities because they are being developed in the context of the mission approach to tackle some of

Vision and Goal Self-concordance

Goal self-concordance has been shown to have enduring influences on behavior. It predicts sustained effort and increased goal-attainment. Compared to goals that lack self-concordance, self-concordant goals generate greater satisfaction and increased well-being. One research strand where vision and goal self-concordance have been studied as integrated dimensions in behavior-steering processes is wo

Challenges Facing Components Reuse in Industrialized Housing : A literature review

Concerns over the earth’s ability to sustain itself over the long term as a consequence of human consumption of natural resources points towards sustainable development. Since a large proportion of human consumption is linked to buildings and construction, this means managing the construction process in more sustainable ways. Strategies that target greater material efficiency and which promote cir

Is the Universe Infinite? Characterising a Hierarchy of Reasoning in Student Conceptions of Cosmology Concepts Using Open-Ended Surveys

Cosmology presents students with ideas that stimulate their curiosity and brings together various concepts from STEM that call on a variety of reasoning types across multiple representational modes, involving subtleties of spacetime relations, a variety of models and evidence requiring multiple lines of high precision observations. This study investigated high school students’ levels and types of

Application of multi-objective optimisation for resolving conflicts when selecting windows

Sweden passed legislation to achieve a target of net zero greenhouse gas emissions by the end of 2045. The Energy Performance of Building Directive further obliged European countries to ensure zero-energy building codes and improve the quality of indoor environments when buildings are renovated, as approximately 40% of total greenhouse gas emissions in Sweden are produced while heating buildings.