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Molecular Genetic Characterization of Acute Lymphoblastic Leukemia with a Poor Prognosis

Popular Abstract in Swedish Leukemi kännetecknas av en okontrollerad tillväxt av omogna vita blodkroppar och orsakas av förvärvade genetiska förändringar. Genetiska förändringar eller avvikelser, som är drivande i cancerutvecklingen, uppstår när normala celler delar sig. Identifiering av sådana förändringar på gen-och kromosomnivå är av stor klinisk betydelse. Behandling styrs av vilka genetiska aAcute lymphoblastic leukemia (ALL) affects individuals at all ages, with peak incidences in children <4 years and adults >50 years. ALL is broadly categorized into B-cell precursor (BCP) and T-cell ALL with specific clinical features associated with outcome. In contrast to pediatric ALL, which has a favorable prognosis, adult ALL is associated with a much poorer outcome with less than 40% overall

"Här lyktas Konunga styrsl" : en komparativ studie kring senmedeltida och tidigmodernt fursteideal i Västeuropa

Den här uppsatsen handlar om förhållandet mellan senmedeltida och tidigmodernt fursteideal. Studien är en komparativ idéanalys mellan den svenska "Konungastyrelsen" och Machiavellis "Fursten". Genom att anlägga politisk kultur som analytiskt redskap visar jag att det finns en idéhistorisk kontinuitet, med vissa brott och förändringar, i det västeuropeiska fursteidealet.This paper examines the relationship between late medieval and early modern princely ideals. The study is a comparative analysis of ideas between the Swedish "Konungastyrelsen" and Machiavelli's "Prince". By using political culture as an analytical tool, I show that there is a historical continuity in ideas, with some changes, in the Western European principality ideal.

Reading with Reference - A Study of the Limits of Formalist Criticism

This thesis intends to point out the limits of exclusively formalist literary criticism. To locate these limits with precision the thesis contrasts the formalist criticism of Monroe C. Beardsley with the critical hermeneutics of Paul Ricoeur. The idea for this thesis is based in an experience that strictly rule-governed formalist criticism does not seem to correspond to the fullness of its object,

Barn ska inte vara brickor i ett politiskt spel : en komparativ studie av Rysslands adoptionslagstiftning i förhållande till internationella riktlinjer kring adoption

The Russian Federation decided in late 2012 to ban adoptions to the United States. The adoption ban has been criticized from several directions for being motivated politically and that it did not take into account the children who were waiting for an adoption to the United States. Children who go through an adoption are often found in an unusually vulnerable position. Not only have they lost their

”För oss ett offer vorden”. Läran om mässoffret i högkyrkliga mässordningar från 1930 till idag

Allt sedan sitt genombrott på 1930-talet har den s.k. högkyrkliga rörelsen, eller bättre uttryckt Kyrklig förnyelse, på ett eller annat sätt eftersträvat ett betonande av offermotivet i mässans firande. Detta har inte minst framgått av de mässordningar som producerats inom ramen för rörelsen och av till rörelsen anknutna personer. Mässofferläran, som teorin traditionellt kallas, har diskuterats ocThe Swedish High Church movement has, ever since its breakthrough in the 1930s, in one way or another struggled to accentuate the sacrificial motif in the celebration of the Mass. This is something that especially can be noted in the missals that have been produced within the movement, and by persons connected to it. The doctrine of the Sacrifice of the Mass, as this theory is known traditionally,

Insulation reduction of footwear: 1-day sweating test on a thermal foot model

The present paper is discussing some results of the bigger experiment that was conducted in order to study the effect of different sweat rates (3, 5 and 10 g/h) on footwear insulation. During the study series some tests with 8-hour sweating were carried out. A thermal foot model was used for testing. The model is divided into 8 zones and had 5 “sweat glands”. A thin sock was donned on foot model f

Modeling vegetation and ecosystem responses to climate change and fire regime

Climatic fire danger will likely increase because more droughts and heat-waves are caused by climate change. Climate change can shift fires from occurring only rarely to regularly in ecosystems not until now adapted to fire. We applied dynamic vegetation-fire models to investigate these future responses. The future of fire in Mediterranean-type ecosystems depends strongly on changes in vegetation

Threats of projected changes in fire regime for newly affected areas in Europe and Northern Africa

Under climate change conditions, climatic wildfire danger could also increase in ecosystems not dominated by fires until now. This increasing trend could lead to more area burned in the future. We have developed an algorithm to map new fire-prone areas in Europe and Northern Africa that identifies grid points where a rare fire event is becoming the mean at the end of the 21st century. When applyin

The Haunting of the Automated Gaze

This article analyzes the artistic exploration of machine vision in the video installation Modern Escape (2018) by Danish artist duo Hanne Nielsen and Birgit Johnsen. The artwork recreates a modern Western home pervaded by surveillance technologies and the automated vision of a robotic vacuum cleaner. The main conceptual idea of the work is the automated gaze, and with few exceptions, all the scen