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Development of relevant models of Parkinson's disease (PD) is essential for a better understanding of the pathological processes underlying the human disease and for the evaluation of promising targets for therapeutic intervention. To date, most pre-clinical studies have been performed in the well-established rodent and non-human primate models using injection of 6-hydroxydopamine (6-OHDA) or 1-me
Abstract is not available
Departing from three metaphors—the body as gift, resource, and commodity—the book explores the contemporary exchange of organs, tissues, and cells. Although the gift is the sanctioned metaphor for donating parts of the body, the underlying perspective from the side of states, authorities, and the medical establishment often seems to be that the body shall be understood as a resource. But medicine,
The article examines Singaporeans' experiences of upward social mobility and how traditional gender roles within the family are renegotiated and reinterpreted in Singapore. When the former British colony gained independence in 1965 its post-colonial government embarked on an ambitious modernization programme, under which villages were demolished and residents relocated to new high-rise estates, fa
The antitumor properties of melatonin (MLT) are known for prostate cancer cells. This study investigated whether MLT affects prostate maturation and interferes with tissue injuries induced by diabetes. MLT was administered to Wistar rats from 5 weeks of age in the drinking water (10 μg/kg b.w.), and diabetes was induced at the 13th week by streptozotocin (4.5 mg/100g b.w., i.p.). The animals were
Lymphomas belong to the few cancer sites with increasing incidence over past decades, and only a few risk factors have been established. We explored the association between education and the incidence of lymphoma in the prospective EPIC study. Within 3,567,410 person-years of follow-up, 1,319 lymphoma cases [1,253 non-Hodgkin lymphomas (NHL) and 66 Hodgkin lymphomas (HL)] were identified. Cox prop
This study investigates the relationship between the understanding of Jesus as the only teacher and the transmission of the Jesus tradition in the community behind the Gospel of Matthew.
Thermal manikins have been used to measure thermal properties of clothing. The use of thermal manikins has made a step forward in terms of quantifying thermal properties of clothing in a 3-D manner compared with the use of hotplates for material testing. The effects of clothing properties measured on the thermal manikins under steady state (constant manikin surface temperature and constant environ
Popular Abstract in Swedish Det är dans i parken ikväll: Om samverkan mellan näringsliv och akademi med forskningsparken som mäklande miljö och aktör Många anser att gapet mellan näringsliv och akademi behöver överbryggas. I olika sammanhang konstateras dock att det finns svårigheter att få till stånd täta relationer parterna emellan. Därför har en rad olika initiativ tagits för att underlätta läThe aim of this thesis is to examine interaction between the business community and academia, and consider the Science Park as a brokering environment and actor. The bulk of park-oriented research, like park-related practice, is based on network theory and thinking. Taking such an approach, it is natural to study the intensity and nature of the interactions of the involved parties – in this case,
Popular Abstract in Swedish Melatonin är ett hormon som produceras i, och frisätts från pinealorganet hos ryggradsdjur. Melatoninets viktigaste uppgift är att till hjärnan förmedla signalen om nattens längd, d.v.s vilken årstid det är. Produktionen och frisläppningen sker rytmiskt med den högsta nivån under natten. Melatoninet transporteras ut i kroppen via blodet och binder till särskilda mottagaMelatonin is a neurohormone which mediates photoperiodic signals from the pineal organ to the brain. GABA (g-aminobutyric acid) is the major inhibitory transmitter in the central nervous system. It has previously been suggested that functional interaction exists between central binding sites for GABA/benzodiazepines (GABAA/bzd receptors) and melatonin in the central nervous system, and that GABA a
Popular Abstract in Swedish Bostadsanpassning är en vanlig åtgärd inom kommunal service och rehabilitering. Avsikten är att ta bort fysiska miljöhinder i bostaden och den nära utemiljön för underlätta vardagliga aktiviteter och möjliggöra ett självständigt liv. Enligt svensk plan- och bygglagstiftning skall alla bostäder som byggs eller genomgår omfattande renoveringar vara tillgängliga och användHousing adaptation is a common intervention, in Sweden granted by municipal authorities, and performed in order to remove environmental barriers and enhance daily activities. In spite of increasing costs, efficient strategies for evaluation of the intervention are lacking. In this thesis, occupational therapy clients living in a south Swedish municipality and receiving housing adaptation grants we
Background The contribution of genetic variation in DNA repair genes to gastric cancer (GC) risk remains essentially unknown. The aim of this study was to explore the relative contribution of DNA repair gene polymorphisms to GC risk and severe chronic atrophic gastritis (SCAG). Method A nested case control study within the EPIC cohort was performed including 246 gastric adenocarcinomas and 1175 ma
The diurnal and vertical variability of heat and carbon dioxide (CO2) in the atmospheric surface layer are studied by analyzing measurements from a 213 m tower in Cabauw (Netherlands). Observations of thermodynamic variables and CO2 mixing ratio as well as vertical profiles of the turbulent fluxes are used to retrieve the contribution of the budget terms in the scalar conservation equation. On the
