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Background: Artificial intelligence (AI) is about to transform medical imaging. The Research Consortium for Medical Image Analysis (RECOMIA), a not-for-profit organisation, has developed an online platform to facilitate collaboration between medical researchers and AI researchers. The aim is to minimise the time and effort researchers need to spend on technical aspects, such as transfer, display,

In this study, we present a combined small-angle neutron and X-ray scattering (SANS and SAXS) study of the nanoscale structure of cortical bone specimens from three different species. The variation of the scattering cross section of elements across the periodic table is very different for neutrons and X-rays. For X-rays, it is proportional to the electron density while for neutrons it varies irreg

OBJECTIVES: Clinical presentation of primary Sjögren's syndrome (pSS) varies considerably. A shortage of evidence-based objective markers hinders efficient drug development and most clinical trials have failed to reach primary endpoints.METHODS: We performed a multicentre study to identify patient subgroups based on clinical, immunological and genetic features. Targeted DNA sequencing of 1853 auto

Spinocerebellar ataxia type 3 (SCA3), caused by a CAG repeat expansion in the ataxin-3 gene (ATXN3), is characterized by neuronal polyglutamine (polyQ) ATXN3 protein aggregates. Although there is no cure for SCA3, gene-silencing approaches to reduce toxic polyQ ATXN3 showed promise in preclinical models. However, a major limitation in translating putative treatments for this rare disease to the cl

#104_loga, a nonlinear scale of time, for tpt, tbn. “loga, a nonlinear scale of time” refers to the illusion of nonlinear time perception. This idea suggests that our estimation of time intervals whether on a small (milliseconds) or large (decades) scale should be logarithmic, giving us a subjective experience very different from clock or calendar. Of course, our perception of time is influenced b

#100. ASEAN Voices, for erhu and 10 mixed ASEAN ensemble players (2017). Premiere: Premiered by C asean Consonant (an ASEAN traditional ensemble), during the 2017 China-ASEAN Music Week at the Guangxi University of the Arts on May 27, 2017. The conductor was Knote KnocKnote with erhu soloist Hu Liu.

Living in a complex and dynamically changing environment requires accurate and timely behavioural responses that allow for adapting to such changes. Well-developed perceptual systems provide a continuous flow of abundant and up-to-date information on the changes in the environment, and, thereby, allow for tailoring behavioural responses accordingly. However, issuing any behavioral response would n

We detail here the convergence properties of a new model-independent imaging method, the Lévy expansion, that seems to play an important role in the analysis of the differential cross section of elastic hadron-hadron scattering. We demonstrate, how our earlier results concerning the Odderon effects in the differential cross-section of elastic proton-proton and proton-antiproton scattering as well

PURPOSE: Analyze the goals for treatment and attained goals for spinal orthoses in children with cerebral palsy (CP), and describe the use of spinal orthoses in relation to age, sex, gross motor function, and scoliosis. METHODS: Cross-sectional data for all children born between 2000 and 2014 and registered in the Swedish CP registry were analyzed in relation to age, sex, Gross Motor Function Clas

In this contribution a practical and rational decision-making approach is presented to be applied for common bridges typically managed by public authorities. The authors have developed a model with the intention to be applicable for practical cases for common bridges in the daily work of bride operators responsible for a large number of assets, yet still maintain the principles of more generic fra

As urban systems continue to grow worldwide, urban peripheries increase in number and typologies, which makes their planning a challenge for sustainable development. The aim of this article is to explore approaches and challenges related to the application of sustainable planning to urban peripheries. We reviewed the content of 102 papers related to sustainable planning in urban peripheries by app

Adeno Associated Virus (AAV)-mediated gene expression in the brain is widely applied in the preclinical setting to investigate the therapeutic potential of specific molecular targets, characterize various cellular functions, and model central nervous system (CNS) diseases. In therapeutic applications in the clinical setting, gene therapy offers several advantages over traditional pharmacological b

We present a mathematical model for the simulation of the development of an outbreak of COVID-19 in a slum area under different interventions. Instead of representing interventions as modulations of the parameters of a free running epidemic we introduce a model structure that accounts for the actions but does not assume the results. The disease is modelled in terms of the progression of viremia re

Fire safety provisions in building regulation are about managing risk. In order to appropriately characterize and incorporate risk measures into building regulation, it is helpful to view building regulatory systems (BRS) as complex socio-technical systems (STS), wherein there are interactions between institutions, technology and people, which ideally work together to mitigate risk to a societally

Over the last decade, serial crystallography, a method to collect complete diffraction datasets from a large number of microcrystals delivered and exposed to an X-ray beam in random orientations at room temperature, has been successfully implemented at X-ray free-electron lasers and synchrotron radiation facility beamlines. This development relies on a growing variety of sample presentation method