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Aims: Iron deficiency (ID) is comorbid in up to 50% patients with heart failure (HF) and exacerbates disease burden. Ferric carboxymaltose (FCM) reduced HF hospitalizations and improved quality of life when used to treat ID at discharge in patients hospitalized for acute HF with left ventricular ejection fraction <50% in the AFFIRM-AHF trial. We quantified the effect of FCM on burden of disease an

Imaging is an integral part of breast cancer diagnosis, staging and follow-up. Breast imaging is also important for radiation therapy planning. The radiation oncologist needs to review patient’s imaging (e.g. mammography) to evaluate the extent of disease (for radiation planning, not for diagnostic purposes) and for treatment planning. Pre-treatment imaging is the key for planning radiation target

Ecogeographical rules, describing common trends in animal form across space and time, have provided key insights into the primary factors driving species diversity on our planet. Among the most well-known ecogeographical rules are Bergmann's rule and Allen's rule, with each correlating ambient temperature to the size and shape of endotherms within a species. In recent years, these two rules have a

University teachers funded to engage in educational development projects have been found to become increasingly engaged in the scholarship of teaching and learning. However, research also points to obstacles such as departmental culture, lack of support from management, and unhelpful administrative processes. In this study, I interview university teachers and their heads of departments in an educa

The purpose of this chapter is to discuss the legal issues relating to cruise ship passenger contracts, their nature and salient features, parties to the contract and their rights and obligations. Claims arising out of passenger carriage subject to applicable law and contracts containing standard terms and conditions are addressed. It is rare for passengers to examine the terms and conditions of t

Background: Transcatheter aortic valve implantation (TAVI) has shown similar or improved clinical outcomes compared with surgical aortic valve replacement (SAVR) in patients with symptomatic severe aortic stenosis at low risk for surgical mortality. This cost-utility analysis compared TAVI with SAPIEN 3 versus SAVR in symptomatic severe aortic stenosis patients at low risk of surgical mortality fr

Objective: This study was undertaken to assess whether deviations from normal fetal growth are associated with spontaneous preterm delivery. Study design: A population-based study was performed, using Swedish Medical Birth Register data from 1991 through 2001. The total population comprised 1,007,648 singleton births. Intrauterine-derived growth standards were used to identify individual standard

Neurogenin 2 (Ngn2) is a proneural gene involved in neuronal differentiation and subtype specification in various regions of the nervous system. In the ventral midbrain, Ngn2 is expressed in a spatiotemporal pattern that correlates with the generation of mesencephalic dopaminergic (mesDA) neurons. We show here that lack of Ngn2 impairs the development of mesDA neurons, such that less than half of

Dose conversion coefficients relating the kerma free-in-air to effective dose have been studied. In order to do so a sampling scheme encompassing all the risk organs and tissues was developed for the Alderson RANDO phantom. Preliminary results are shown for some specific organs irradiated with a point source in the laboratory.

Background. NT-proBNP may be useful for ruling out heart failure in primary health care. In this study we examined the analytical quality of NT-proBNP in primary health care on the Cobas h 232 point-of-care instrument compared with measurements performed in a hospital laboratory. Materials and methods. Blood samples requested for NT-proBNP were collected in primary health care (n = 95) and in a ho

Popular Abstract in Swedish Patienter, som på grund av lungsjukdom eller annan skada på lungorna inte kan andas tillfredsställande, kan behandlas med hjälp av en respirator som ventilerar lungorna. Respiratorbehandling kan tyvärr tillfoga redan sjuka eller skadade lungor ytterligare skador. Sådana skador kan uppkomma vid ventilation av lungorna vid alltför stora volymer och höga tryck som leder tiThe elastic pressure-volume (Pel-V) curve of the respiratory system can be used as a guide for improved ventilator management. It may indicate risks of lung damage associated with collapse or overdistension of lung units. The work described in this thesis was aimed at developing methods for the determination and characterisation of the Pel-V curve under static and dynamic conditions and at a bette

A considerable amount of evidence from several intonation languages (e.g., German, English, Italian) supports the idea that F0 peak timing, height, and shape variables form a feature bundle, which is used to encode two-fold intonational (e.g., sentence-level) pitch accent distinctions such as L+H* vs. L*+H. The three types of features in the bundle can be weighted differently but the outcome seems