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As structural components of the glycocalyx, heparan sulfate proteoglycans (HSPGs) are involved in multiple pathophysiological processes at the apex of cell signaling cascades, and as endocytosis receptors for particle structures, such as lipoproteins, extracellular vesicles, and enveloped viruses, including SARS-CoV-2. Given their diversity and complex biogenesis regulation, HSPGs remain understud
In this study, two methods for wastewater treatment plant (WWTP) dimensioning were compared: (1) a traditional guideline-based approach, and (2) a mechanistic model-based approach. The design outputs depended on uncertainties in correlated influent concentrations, which emphasises the importance of uncertainty analysis. The results showed that model-based design could simplify and reduce the time
Surtsey island was formed in a volcanic eruption south of Iceland in 1963 – 1967 and has since then been protected and monitored by scientists. It is the youngest island in the Vestmannaeyjar archipelago. The archipelago is of volcanic origin, but the other islands are ca. 5 000 to 40 000 yrs old. The first two moss species were found on Surtsey as early as 1967 and several new bryophyte species w
The use of variable-length genomes in evolutionary computation has applications in optimisation when the size of the search space is unknown, and provides a unique environment to study the evolutionary dynamics of genome structure. Here, we revisit crossover for linear genomes of variable length, identifying two crucial attributes of successful recombination algorithms: the ability to retain homol
Heracula discivitta Moore is an uncommon moth species currently recorded from India, Nepal and China. Although this species has traditionally been placed in Lymantriinae, its systematic position in Macroheterocera has been enigmatic due to its unique morphological features. Here we used molecular and morphological data to explore the systematic position of H. discivitta. Our molecular phylogenetic
Epidemiologic data on pleural mesothelioma are scarce on regional and occupational time trends, which would monitor the effects of changes in exposure to asbestos. We aim to characterize time trends, regional, socioeconomic, and occupational risk factors for pleural mesothelioma in Sweden in the years from 1961 to 1998. The Swedish Family-Cancer Database was used to identify patients with pleural
Epidemiologic data on peritoneal mesothelioma are scarce but exposure to asbestos is an identified risk factor. To characterize the disease, time trends, age-incidence relationships, and occupational risk factors for peritoneal mesothelioma were studied based on the Swedish Family-Database covering years 1961 to 1998. Peritoneal mesothelioma is a rare disease and only 96 male and 113 female cases
Many of today’s health care facilities are outdated and no longer efficiently support processes. The various development trends in changing health care services seem to support more frequent use of modular facilities. Modular facilities and their development, however, face the challenge of combining a customized, user-centric design for special customer needs with the rapid delivery of prefabricat
A search for supersymmetry in events with large missing transverse momentum, jets, and at least one hadronically decaying τ-lepton is presented. Two exclusive final states with either exactly one or at least two τ-leptons are considered. The analysis is based on proton-proton collisions at s=13 TeV corresponding to an integrated luminosity of 36.1 fb-1 delivered by the Large Hadron Collider and re
The aim with this paper is to examine how different GIS-based visualization methods can be applied and come to practical uses in the emergency service’s fire preventive work. These techniques motivate and facilitate various forms of fire prevention such as selection of areas or neighborhoods, blocks or buildings before home visits, identification and targeting of different risk groups and customiz
The aim is to illustrate how web marketing frame commercial baby food as a value-adding part of weaning practice and discuss how various ways of framing relate to contemporary mothering ideals. Drawing on “practice” and “frame analysis,” we illustrate how four baby food producers’ web marketing frame commercial baby food and weaning as “medical,” “fun” or “convenient.” The analysis shows that the
Car-sharing systems with electric vehicles are an alternative to reduce commuting times in big cities and also to mitigate air pollution. Car-sharing exists in 1100 cities around the world. These systems have had positive effects in the cities, replacing between 9 and 23 private vehicles for each car. This document proposes a public car-sharing system for Bogotá. The article focuses on the design
A search for heavy right-handed Majorana or Dirac neutrinos N R and heavy right-handed gauge bosons W R is performed in events with a pair of energetic electrons or muons, with the same or opposite electric charge, and two energetic jets. The events are selected from pp collision data with an integrated luminosity of 36.1 fb −1 collected by the ATLAS detector at s=13 TeV. No significant deviations
Kärn- och elektrondynamik i atomer och molekyler är grunden för många fysiska processer och kemiska reaktioner. Ofta händer denna dynamik på tidsskalor som är så korta att de kallas ultrasnabba.För att studera ultrasnabba fenomen behövs tekniker som pump-prob-experiment med ultrasnabba ljuspulser. För att dessa experiment ska lyckas måste ljuspulsernas egenskaper noga studeras och styras för att dNuclear and electronic dynamics in atoms and molecules are the foundation of many physical processes and chemical reactions. Often, these dynamics take place on timescales so much shorter than those commonly encountered that they are called ultrafast. In order to study ultrafast phenomena, time-resolved techniques such as pump-probe experiments, involving ultrafast light pulses, are necessa
Konferensbidraget presenterar en forskningsplan för studiet av möjligheter och utmaningar behäftade med aggregering (insamling och sammanvägning) av den information som sammanställs i svenska myndigheters risk- och sårbarhetsanalyser.
The artificial bilayer structures of lipids and phospholipids can be fabricated using the Langmuir-Blodgett (LB) technique. High sensitivity and ultrasensitive detection can only be achieved using plasmon-enhanced spectroscopy, such as surface-enhanced Raman scattering (SERS). This chapter describes the single molecule detection of tagged-phospholipids using the LB technique and plasmon-enhanced s
