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Treatment with anti-CD20 antibodies is only moderately efficient in chronic lymphocytic leukemia (CLL), a feature which has been explained by the inherently low CD20 expression in CLL. It has been shown that CD20 is epigenetically regulated and that histone deacetylase inhibitors (HDACis) can increase CD20 expression in vitro in CLL. To assess whether HDACis can upregulate CD20 also in vivo in CLL

Aim: To investigate the fees charged by Swedish dentists for root fillings, coronal restorations and further dental interventions during a follow-up period of 5–6 years. Methodology: A total of 248 299 root fillings were linked with the tooth, the patient and the provider and entered into the Swedish Social Insurance Agency register in 2009. The data register also recorded the subsidy-based (sched

INTRODUCTION: The aim of our study was to develop and use a population pharmacokinetic model for assessment of individual valproate clearance in children and young adults suffering from epilepsy.MATERIAL AND METHODS: The analysis was performed using 52 steady-state concentrations of valproate collected from 26 epileptic patients during the routine clinical practice in our hospital. The mean values

We introduce a general decomposition method applicable to all forms of bivariate rank dependent indices of socioeconomic inequality in health, including the concentration index. The technique is based on recentered influence function regression and requires only the application of OLS to a transformed variable with similar interpretation. Our method requires few identifying assumptions to yield va

This paper investigates if the effect of type 1 diabetes mellitus (T1DM) on school performance has changed over time using national Swedish population register data. The issue is of interest because management and treatment of the disease have improved over the last decades and, furthermore, because of changes in the educational grading system. Despite these changes, data indicate a persistent neg

Ökad cykling har stor betydelse för ett hållbart transportsystem. För att öka andelen resor med cykel måste dock trafik- och cykelplaneringen ta itu med ett flertal olika problem. Det är emellertid inte alltid fullständigt klart vad som behövs gällande planering för att öka cyklingen. Denna rapport är resultatet av en litteraturstudie om hur olika faktor kopplade till cykelplanering påverkar benägIncreased bicycling is of great importance for a sustainable transport system. This report is the result of a literature study concerning how different factors associated with bicycle planning influence the propensity to choose the bicycle for transportation. The literature study was carried out in the search engine GoogleScholar and only scientific papers, articles and books were included. Throug

Objectives: Study formal and informal care of community-living older people in the Swedish National study of Aging and Care (SNAC). Design: Cross-sectional, population based cohort. Setting: Three areas in Sweden: Municipality of Nordanstig, Stockholm and Skåne County. Participants: 3,338 persons ≥72 years. Measurements: Patterns and amounts of informal and formal care by cognition and area of res

Background: General practice systems in the Nordic countries share certain common features. The sector is based on the Nordic model of a tax-financed supply of services with a political objective of equal access for all. The countries also share the challenges of increased political expectations to deliver primary prevention and increased workload as patients from hospital care are discharged earl

This study investigated: (a) the cost and change in hospitalizations related to alcohol misuse for the healthcare sector and (b) the effect of distance to the border on alcohol-related hospitalization costs. The first objective was analyzed using descriptive statistics and the second using ordinary least squares regression on aggregated municipality data. The total cost decreased marginally during

Popular Abstract in Swedish För att ge en god omvårdnad behövs kunskaper om ätproblem som helhet och om möjliga hinder för optimalt näringsintag hos äldre patienter, särskilt de med stroke. Sådana kunskaper behövs eftersom åldrandet i sig självt eller tillsammans med sjukdom, t.ex. stroke och dess följder, kan påverka förmågan att äta och därmed också näringsintaget med ökad risk för såväl undernäThe aim of this thesis was to describe eating difficulties and interventions to improve eating among elderly patients, especially those with stroke, to make comparisons between patients with dysphagia and those without (Papers I & II), those with and without assisted eating (Paper IV), and to analyse the relation between eating difficulties, nutritional status (Papers II-V), pressure ulcers (P

In a geographically defined child population aged 0-15, every twelfth child suffered from chronic illness. Their parents and randomly selected control children's parents were asked about their living conditions using questionnaires. Non-responders (30%) had the same sociodemographic profile as responders. The socioeconomic level in index families (n = 95) was lower than in control families (n = 16

We analyse recent experiments on momentum shearing interferometry of electron wave packets^1,2 by using an optical analogy with shearing interferometry for optical waves. This analogy offers a convenient point of view to discuss the capabilities and difficulties of this technique used to access the phase of electron wave packets.

This article presents a tool to calculate health care costs attributable to overweight in a comparable and standardized way. The purpose is to describe the methodological principles of the tool and to put it into use by calculating and comparing the costs attributable to overweight for The Netherlands, Germany and Czech Republic. The tool uses a top-down and prevalence-based approach, consisting o

Two systems for measurements of absorption and scattering properties, based on picosecond-pulse lasers and single-photon counting detection, were characterized using a detailed protocol. The first system utilizes diode lasers at 660, 785, 910 and 974 nm as light sources. The second employs a Ti:sapphire and a mode-locked dye laser to produce tunable pulses in the range 610 - 1000 nm. Using solid t

Popular Abstract in Swedish Avstår barn i fattiga länder från utbildning framförallt för att de är fattiga eller för att de upplever att skolan inte har något meningsfullt att erbjuda? Svaret på den frågan har stor betydelse för vilken politik som bör föras. Ett empiriskt bidrag till en sådan frågeställning är i vilken utsträckning som utbildning kan tänkas vara ett ?lönsamt? alternativ för indiviWhy do some children in the developing world choose to stay out of school? Is it mainly because poverty leaves them with no options or because schooling seems to offer them few benefits? The answers to these questions have profound policy implications. An empirical input into this discussion is the extent to which schooling can actually be perceived as a profitable option in various countries and,

Popular Abstract in Swedish Luften omkring oss består inte bara av gaser. I den finns det mängder av små partiklar. De partiklar som står i fokus i den här avhandlingen är mindre än 10 μm, vilket endast är en femtedel av ett hårstrås diameter. Dessa partiklar är tillräckligt små för att kunna förflyttas långa sträckor i atmosfären och har dessutom visat sig påverka människors hälsa negativt. Man hAerosol particles are found in the whole troposphere. Research regarding these particles has gained increased attention because of the effect the particles have on both health and climate. In the atmosphere, aerosol particles scatter incoming solar radiation and this has a cooling effect on the Earth’s climate. But there are particles, especially those containing soot, which can absorb sun light a

Examensarbetets titel: Marknadsföringsetik - inte helt utan problematik - En kvalitativ studie om hur byråer i marknadsföringsbranschen hanterar etiskt beslutsfattande i traditionella och digitala medier. Seminariedatum: 2020-01-16 Ämne/kurs: FEKH29, Examensarbete i marknadsföring på kandidatnivå, 15 högskolepoäng Författare: Rebecka Bäcklin, Frida Lindgren, Elias Sovre Handledare: Burak Tunca NTitle: Marketing ethics - not entirely without problematics - A qualitative study of how agencies in the marketing industry handle ethical decision making in traditional and digital media. Seminar date: 2020-01-16 Course: FEKH29, Business Administration: Bachelor Degree Project in Marketing Undergraduate Level, 15 University Credit Points Authors: Rebecka Bäcklin, Frida Lindgren, Elias Sovré A

This thesis examines how learning is depicted in policy documents for public libraries on municipal and national level in Sweden. The documents analyzed are library plans from five Swedish cities, as well as the proposal for a national strategy presented in 2019 by the National Library of Sweden. The method used is Carol Bacchi’s What’s the problem represented to be-approach. Pierre Bourdieu’s the