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Everyday millions of bioanalyses are performed in clinical laboratories, hospitals and research centers, where technicians and bio-analysts utilize analytical chemistry principles and instruments to serve medicine and biomedical research. A method routinely used for sample preparation in bioanalysis is solid-phase extraction (SPE). SPE is a simple method to extract an analyte from a sample matrix
Recent advancements in almost all aspects of hemophilia treatment have vastly improved patient care and management, and new and emerging treatments hold the promise of further progress. However, there remains a scarcity of data on long-term outcomes in hemophilia, particularly among those patients with inhibitors, for whom no validated outcome assessment tools are currently available. At the 15th
Over the past three decades, a range of attempts have been made to raise the importance of science, technology and innovation on the policy agenda in Africa. This article explores four themes along which growth paths and patterns may be realized, namely regional and global integration, inclusive innovation, priorities and approaches to diversify African economies, and the role of the state. The ou
The automatic detection and classification of stance (e.g., certainty or agreement) in text data using natural language processing and machine learning methods create an opportunity to gain insight into the speakers' attitudes towards their own and other people's utterances. However, identifying stance in text presents many challenges related to training data collection and classifier training. In
This paper reviews biokinetic data for ionic indium, and proposes a biokinetic model for systemic indium in adult humans. The development of parameter values focuses on human data and indium in the form of ionic indium(III), as indium chloride and indium arsenide. The model presented for systemic indium is defined by five different pools: plasma, bone marrow, liver, kidneys and other soft tissues.
OBJECTIVE: To investigate the relationship of hospital admissions due to unexplained syncope and orthostatic hypotension (OH) with subsequent cardiovascular events and mortality.METHODS: We analysed a population-based prospective cohort of 30 528 middle-aged individuals (age 58±8 years; males, 40%). Adjusted Cox regression models were applied to assess the impact of unexplained syncope/OH hospital
OBJECTIVE - Ketosis-prone diabetes (KPD) is an emerging, heterogeneous syndrome. A sound classification scheme for KPD is essential to guide clinical practice and pathophysiologic studies. Four schemes have been used and are based on immunologic criteria, immunologic criteria and insulin requirement, BMI, and immunologic criteria and β-cell function (Aβ classification). The aim of the present stud
HIV and Mycobacterium tuberculosis (MTB) are two widespread and highly successful microbes whose synergy in pathogenesis has created a significant threat for human health globally. In acknowledgement of this fact, the European Union (EU) has funded a multinational support action, the European Network for global cooperation in the field of AIDS and TB (EUCO-Net), that brings together experts from E
It has long been known that humans use the focus of expansion (FOE) in a radial optic flow pattern to perceive their instantaneous direction of self-motion (heading). Here we report that motion-streak-like form information is also used for heading perception. We presented observers with an integrated form and motion display in which the dot pairs of a radial Glass patterns were oriented toward one
This paper proposes a simple framework to model social preferences in a way that explicitly separates economic incentives from social (context) effects and allows for uncertainty also about the latter. Moreover, it allows non-economic cost associated with the deviation from some norm to be more discriminatory than just “right” or “wrong.” We refer to existing evidence on dictator game giving to de
This paper revisits the Swedish banking crisis (1919-26) that materialized as post war deflation replaced wartime inflation (1914-18). Inspired by Fisher’s ‘debt deflation theory’, we employ survival analysis to ‘predict’ which banks would fail, given certain ex-ante bank characteristics. Our tests support the theory; maturity structures mattered most in a regime of falling prices, with vulner
Surface hydrophobization of cellulose nanomaterials has been used in the development of nanofiller-reinforced polymer composites and formulations based on Pickering emulsions. Despite the well-known effect of hydrophobic domains on self-assembly or association of water-soluble polymer amphiphiles, very few studies have addressed the behavior of hydrophobized cellulose nanomaterials in aqueous medi
It’s clear that human activities have heated our climate via the release of anthropogenic greenhouse gases. Recent changes within the earth climate are rapid, intensifying, and unprecedented. With each additional increment of warming, climate change is impacting ecosystems through changes in average conditions, climate variability, coupled with other associated changes such as biodiversity loss an
To decrease the complexity of motion-planning optimizations, a segmentation and merging strategy for maneuvers is proposed. Maneuvers that are at-the-limit of friction are of special interest since they appear in many critical situations. The segmentation pointsare used to set constraints for several smaller optimizations for parts of the full maneuver, which later are merged and compared withopti
All over the world there is a shortage of adequate, affordable housing that enables social integration and sustainability. Many individuals and households have access to housing but live in different kinds of involuntary isolation with respect to age, gender, income, culture and ethnic background. There is a lack of housing forms that can contribute to solving these societal challenges through dif
