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Background Both internet-based cognitive-behavioural therapy (ICBT) and physical exercise are alternatives to treatment as usual (TAU) in managing mild to moderate depression in primary care.Aims To determine the cost-effectiveness of ICBT and physical exercise compared with TAU in primary care.Method Economic evaluation of a randomised controlled trial (N = 945) in Sweden. Costs were estimated by
The response of a coupled atmosphere-ocean general circulation model to insolation representative of 6000 years ago has been studied with a set of 1000-year quasi-equilibrium simulations. Comparison with similar experiments with an uncoupled atmosphere general circulation model demonstrates the importance of an interactive ocean for the climate signal. The model simulates an intensification of the
In this report, we present a novel modular approach to the immobilization of a high density of boronic acid ligands on thermoresponsive block copolymer brushes for effective enrichment of glycoproteins via their synergistic multiple covalent binding with the immobilized boronic acids. Specifically, a two-step, consecutive surface-initiated atom transfer radical polymerization (SI-ATRP) was employe
Lung cancer is a common cancer type associated with poor prognosis. Even in the group of patients with earlystage tumors, for which curative treatment is possible, lung cancer recurrence is frequent. The aim of this thesis was to investigate the potential prognostic role of mutations in tumor specimens, blood-based proteins and circulating tumor DNA.In study I, we performed EGFR mutation detection
Membrane spacers are an essential part of spiral wound modules and can significantly influence the mass transfer performance and pressure drop in the modules. To develop further understanding of the importance of spacer selection, the performance of two configurations of parallel spacers for ultrafiltration using Dextan T40 was analysed in this study using lab-scale experiments and CFD simulation
The properties of laser wakefield accelerated electrons in supersonic gas flows of hydrogen and helium are investigated. At identical backing pressure, we find that electron beams emerging from helium show large variations in their spectral and spatial distributions, whereas electron beams accelerated in hydrogen plasmas show a higher degree of reproducibility. In an experimental investigation of
A pulsed millimeter wave radar operating at a frame rate of 144 Hz is utilized to record 2160 scattering signatures of 12 generic hand gestures. Gesture recognition is achieved by machine learning, utilizing transfer learning on a pretrained convolutional neural network. This yields excellent classification results with a validation accuracy of 99.5%, based on a 60% training versus 40% validation
Studies of fully-reconstructed jets in heavy-ion collisions aim at extracting thermodynamical and transport properties of hot and dense QCD matter. Recently, a plethora of new jet substructure observables have been theoretically and experimentally developed that provide novel precise insights on the modifications of the parton radiation pattern induced by a QCD medium. This report, summarizing the
This paper presents the design and features of frequency-selective wallpaper-based on periodic and symmetric metallic hexagons-intended to be attached to standard walls for filtering out 5GHz signals (e.g., IEEE 802.11a systems)without blocking other selected radio communication services (e.g., cellular mobile communication signals). It analyzes the characteristics of the radio channel-as found wi
Metabolic responses to food influence risk of cardiometabolic disease, but large-scale high-resolution studies are lacking. We recruited n = 1,002 twins and unrelated healthy adults in the United Kingdom to the PREDICT 1 study and assessed postprandial metabolic responses in a clinical setting and at home. We observed large inter-individual variability (as measured by the population coefficient of
This article addresses forward motion control for trajectory tracking and mobile formation coordination for a group of nonholonomic vehicles on SE(2). First, by constructing an intermediate attitude variable which involves vehicles' position information and desired attitude, the translational and rotational control inputs are designed in two stages to solve the trajectory tracking problem. Second,
III-nitrides are considered the material of choice for light-emitting diodes (LEDs) and lasers in the visible to ultraviolet spectral range. The development is hampered by lattice and thermal mismatch between the nitride layers and the growth substrate leading to high dislocation densities. In order to overcome the issue, efforts have gone into selected area growth of nanowires (NWs), using their
Different methods of trapping radioactive xenon are reviewed. Trapping by adsorption on activated charcoal has the advantage of being simple and cheap and also makes it possible to recycle the xenon. An activated charcoal trapping system is described which can extract 133Xe from 100l of expired air in 10 min from patients undergoing diagnostic pulmonary or circulation studies. Details of the const
This paper proposes a framework for the planning of the structural integrity and risk management (SIRM) of offshore structures by utilizing the value of information and action (VoIA) analysis. Multiple structural health information sources, i.e. inspections, structural health monitoring (SHM) and damage detection systems (DDS), are modeled in dependency of the information acquirement state. In the
This paper presents a new accelerated testing procedure for plastic gears that is based on several different levels of testing. The iterative testing procedure fulfils requests from the product development process. The following criteria are considered for testing: reduced number of tests, shorter test time and reliable results for different applications. The proposed method was applied over the f
