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Does morality need justification? And if yes, what kind of justification will do the proper job? Peter Danielson distinguishes between fundamental and non-fundamental justification. A fundamental justification is a justification of a realm that does not appeal to any of the concepts of that realm. In the case of morality this means a justification formulated in amoral or non-moral terms. A non-fun
Purpose: The purpose of this study was to investigate how theories regarding core values and cultural shifts could contribute to the segmentation research field. The aim of this study was further to investigate how to attract an additional segment without loosing the original target audience. To exemplify we did a case study regarding whether it is possible for, an existing brand operating in the
This master thesis explores commercialization of electric road systems in urban environments, using a combined methods approach, in contrast to previous studies that have focused on long haul transportation. First, through interviews and document gathering, a stakeholder map was constructed, and the incentives of the identified stakeholders were analyzed. The thesis found disagreements between the
Recent years have seen an explosion in innovative and sustainable mobility service offerings, especially car sharing and bike sharing. The latter contribute to sustainability by reducing individual car ownership, which has negative social, economic and especially environmental consequences. Yet, both industrial and academic discourses point out that no single mobility service is enough to meet the
“Buy one – get one free!” is one of hundreds of commercial messages you see every day. Recent research has concluded what salespeople have known for decades; there is something peculiar about offers involving the concept of free. Suddenly people start to behave irrationally and make choices far from the predictable safe havens of classical economic theory. This thesis test the existence of a zero-
China’s economic development since the beginning of the reform in 1978 has been impressive. Regardless of China’s poor financial banking system and lack of legal enforcements, the growth of Chinese firms makes China’s GDP one of the fastest growing in the world. This paper endeavors to answer the question of formal financial system or its counterpart the alternative informal finance are associated
A significant part of IS systems implemented today introduce a mandatory use environment for their users, where daily tasks and responsibilities are dependent on or even impossible without the use of a specific system. This paper focuses on examining the relevance, importance and potential effects of user satisfaction in these kinds of environments, with the purpose of contributing to this previou
Purpose: The purpose of this study was to explore the importance of local physical tissue support for homeostasis in the isolated retina. Methods: Full-thickness retinal sheets were isolated from adult porcine eyes. Retinas were cultured for 5 or 10 days using the previously established explant protocol with photoreceptors positioned against the culture membrane (porous polycarbonate) or the Mülle
Depressive/anxiety disorders are the most common types of mental illnesses in the world. The present study was the first to explore the association between plasma microRNAs (miRNAs) and depression/anxiety in primary care patients.
This article applies a global value-chain framework to the tobacco industry in Malawi, showing how cigarette manufacturers govern the chain and control first-tier suppliers, the leaf merchants. Contract farming offers smallholders the ability to meet manufacturers' compliance and traceability requirements and an opportunity for process and product upgrading, but threatens to exclude poorer growers
This study was undertaken to determine whether the production of melatonin, a hormone regulating sleep in relation to the light/dark cycle, is altered in Huntington's disease. We analyzed the circadian rhythm of melatonin in a 24-hour study of cohorts of control, premanifest, and stage II/III Huntington's disease subjects. The mean and acrophase melatonin concentrations were significantly reduced
Spridningskoefficienter baserade på färgförsök beräknas
Cocaine and amphetamine-regulated transcript (CART) is expressed in pancreatic islet cells and neuronal elements. We have previously established insulinotropic actions of CART in human and rodent islets. The receptor for CART in the pancreatic beta cells is unidentified. We used RNA sequencing of Cartpt knockdown (KD) INS-1 832/13 cells and identified GPR162 as the most Cartpt-regulated receptor.
BACKGROUND: Several molecular classification systems for bladder cancer have been proposed, but due to differences on how to define molecular subtypes, controversies and misunderstandings have arisen. OBJECTIVE: To discuss different aspects of the molecular classification of bladder cancer and to point to the consequences of using different conceptual approaches. To question some underlying assump
Aim: To explore whether physiotherapy use is increased after hospitalization with COVID-19 with or without respiratory support vs. other respiratory tract infections (RTI). Methods: In all Norwegian residents aged 18–80 years who were hospitalized with COVID-19 (N = 5,344) or other RTI (N = 82,235) between July 1st 2017 and August 1st 2021, we used a pre-post study design to explore the weekly ind
This paper demonstrates how nostalgia entices consumers to re-circulate objects rather than discard them. Through multimethod qualitative inquiry into the Danish vintage cycling community, this paper highlights how consumers’ nostalgic attachment to the biographies of old objects propels re-circulation. The analysis builds on three distinct modes of nostalgia: reluctant, progressive, and playful n
