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The proportion of meals the Europeans eat outside their home steadily increases. We take coffee breaks at work, eat lunch in the office canteen, we order take-away, we go to cafés or pubs to spend time with our friends, we easily grab a snack in vending machines and we eat on airplanes and trains to just mention a few examples. Eating out is nowadays more of an everyday activity than a luxury even

The brackish water cyanobacterium Nodularia spumigena produce the hepatotoxic cyclic pentapeptide nodularin. Intoxications for both human as well as animal may arise when water reservoirs are contaminated with potentially toxic Nodularia species. Here, results of three independent methods for the determination of nodularin in different strains of N. spumigena are presented. The results obtained wi

OBJECTIVE: Critical limb ischemia (CLI) is a peripheral arterial disease manifested by drastically diminished blood flow to the legs, pain at rest, nonhealing wounds, and gangrene caused by atherosclerosis. Significant tissue necrosis is associated with late stage CLI and the patients have a poor prognosis. Necrotic and apoptotic cells activate complement and bind complement inhibitor C4b-binding

Consider a parametrized family of general hidden Markov models, where both the observed and unobserved components take values in a complete separable metric space. We prove that the maximum likelihood estimator (MLE) of the parameter is strongly consistent under a rather minimal set of assumptions. As special cases of our main result, we obtain consistency in a large class of nonlinear state space

In 2004 at the ATLAS (A Toroidal LHC ApparatuS) combined test beam, one slice of the ATLAS barrel detector (including an Inner Detector set-up and the Liquid Argon calorimeter) was exposed to particles from the H8 SPS beam line at CERN. It was the first occasion to test the combined electron performance of ATLAS. This paper presents results obtained for the momentum measurement p with the Inner De

Evacuation models generally include the use of distributions or probabilistic variables to simulate the variability of possible human behaviours. A single model setup of the same evacuation scenario may therefore produce a distribution of different occupant-evacuation time curves in the case of the use of a random sampling method. This creates an additional component of uncertainty caused by the i

The mechanisms of neuronal cell death are still only poorly understood, which has hindered the advancement of therapies for many currently untreatable neurodegenerative diseases. This calls for the development of new methods which reveal critical molecular mechanisms of the celldeath machinery with both high sensitivity and cellular resolution. Using animal models for hereditary neurodegeneration

In this contribution, a micro-mechanically motivated, energy relaxation-based constitutive model for phase transformation, martensite reorientation and twin formation in shape memory alloys is proposed. The formulation builds on an idealized parametrization of the austenite-twinned martensite microstructure through first- and second-order laminates. To estimate the effective rank-one convex energy

Context. The ESA space astrometry mission Gaia, planned to be launched in 2013, has been designed to make angular measurements on a global scale with micro-arcsecond accuracy. A key component of the data processing for Gaia is the astrometric core solution, which must implement an efficient and accurate numerical algorithm to solve the resulting, extremely large least-squares problem. The Astromet

L-type voltage-gated Ca2+ channels are expressed in the plasma membrane of muscles, neurons and endocrine cells where they serve as conductors of signals regulating cellular responses to changes in environment. Malfunctions of channels, as well as deregulations of their activity underlie numerous disorders and diseases commonly called channelopathies. In β-cells Ca2+ channels are central players f

The article may be seen as a sequel to my paper delivered at a conference on art historical subjectivity and methodology in Stockholm 1999, initiated by Margaretha Rossholm Lagerlöf. – Now I will try to move that analysis a little step further by discussing some problems concerning the more explicit performative effects and experiences of everyday technical objects and their occasionally strange v

Selected reaction monitoring mass spectrometry (SRM-MS) is a targeted proteomics technology used to identify and quantify proteins with high sensitivity, specificity and high reproducibility. Execution of SRM-MS relies on protein-specific SRM assays, a set of experimental parameters that requires considerable effort to develop. Here we present a proteome-wide SRM assay repository for the gram-posi

Pneumothorax occurs more frequently in the neonatal period than at any other time of life and is associated with increased mortality and morbidity. It may be treated with either needle aspiration or insertion of a chest tube. The former consists of aspiration of air with a syringe through a needle or an angiocatheter, usually through the second or third intercostal space in the midclavicular line.

Adoption of ECMR 4064/89 filled a lacuna in European Merger Control. One of the key objectives behind the ECMR is to prevent a concentration leading to the creation or strengthening of a dominant position which may lead to the prohibition in Article 2 (3).The Commission of the European Communities gained some significant powers in order to protect the competitive structure of Common Market. But, A

The European project has, since its birth in the 1950´s, transformed into a supranational organization with strong constitutional features. The current legal order of the Union has developed into a complex system that is hard to comprehend. Together with the enlargement eastwards, the need for a simplified European Treaty has been intensified. Today, the debate about a European constitution is a t

Created in the aftermath of the Second World War, the main task of the UN is the maintenance of international peace and security. Although the UN Charter, signed in San Francisco in 1945, has remained almost the same, the world has changed. In order to adapt the Charter to new upcoming problems two main possibilities exist. The Charter can either be changed itself, following the procedure set fort